Patents by Inventor Qiongzheng HU

Qiongzheng HU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORCE-MODULATED HYBRIDIZATION FOR VISUALIZING NUCLEIC ACID LENGTH AND FUNCTION
    Publication number: 20230160003
    Abstract: Embodiments of the present disclosure pertain to methods of utilizing force-modulated hybridization to determine the length of an analyte strand, to determine an unknown nucleic acid sequence, or to determine the binding of a nucleotide to an active agent. Additional embodiments of the present disclosure pertain to sample holder devices and methods of utilizing such devices. Further embodiments of the present disclosure pertain to detection devices.
    Type: Application
    Filed: June 11, 2018
    Publication date: May 25, 2023
    Applicant: University of Houston System
    Inventors: Shoujun Xu, Qiongzheng Hu, Yuhong Wang
  • Exchange-induced remnant magnetization for label-free detection of DNA, micro-RNA, and DNA/RNA-binding biomarkers
    Patent number: 10640813
    Abstract: A method of using an exchange-induced remnant magnetization (EXIRM) technique for label free detection of short strands of nucleotides and cancer biomarkers, such as DNA and microRNA strands, DNA/RNA-binding biomarkers, and cancer-specific antigens, with high sensitivity, high specificity, and broad dynamic range. The method may provide a label-free approach aimed to facilitate high reliability, and to require a minimum amount of biochemical reagents.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: May 5, 2020
    Assignee: University of Houston System
    Inventors: Shoujun Xu, Li Yao, Yuhong Wang, Qiongzheng Hu, Haopeng Yang
  • EXCHANGE-INDUCED REMNANT MAGNETIZATION FOR LABEL-FREE DETECTION OF DNA, MICRO-RNA, AND DNA/RNA-BINDING BIOMARKERS
    Publication number: 20190048403
    Abstract: A method of using an exchange-induced remnant magnetization (EXIRM) technique for label free detection of short strands of nucleotides and cancer biomarkers, such as DNA and microRNA strands, DNA/RNA-binding biomarkers, and cancer-specific antigens, with high sensitivity, high specificity, and broad dynamic range. The method may provide a label-free approach aimed to facilitate high reliability, and to require a minimum amount of biochemical reagents.
    Type: Application
    Filed: October 25, 2018
    Publication date: February 14, 2019
    Applicant: University of Houston System
    Inventors: Shoujun XU, Li YAO, Yuhong WANG, Qiongzheng HU, Haopeng YANG
  • Sequence and chiral selectivity of DNA-drug interactions revealed by force spectroscopy
    Patent number: 9778249
    Abstract: Methods of quantifying the efficiency of a drug molecule for its targeted receptor, using a differential binding force to quantify the efficiency of a drug molecule to its targeted receptor.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: October 3, 2017
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Shoujun Xu, Qiongzheng Hu, Yuhong Wang, Te-Wei Tsai
  • SEQUENCE AND CHIRAL SELECTIVITY OF DNA-DRUG INTERACTIONS REVEALED BY FORCE SPECTROSCOPY
    Publication number: 20170234860
    Abstract: Methods of quantifying the efficiency of a drug molecule for its targeted receptor, using a differential binding force to quantify the efficiency of a drug molecule to its targeted receptor.
    Type: Application
    Filed: September 25, 2015
    Publication date: August 17, 2017
    Inventors: Shoujun XU, Qiongzheng HU, Yuhong WANG, Te-Wei TSAI
  • EXCHANGE-INDUCED REMNANT MAGNETIZATION FOR LABEL-FREE DETECTION OF DNA, MICRO-RNA, AND DNA/RNA-BINDING BIOMARKERS
    Publication number: 20140309134
    Abstract: A method of using an exchange-induced remnant magnetization (EXIRM) technique for label free detection of short strands of nucleotides and cancer biomarkers, such as DNA and microRNA strands, DNA/RNA-binding biomarkers, and cancer-specific antigens, with high sensitivity, high specificity, and broad dynamic range. The method may provide a label-free approach aimed to facilitate high reliability, and to require a minimum amount of biochemical reagents.
    Type: Application
    Filed: April 8, 2014
    Publication date: October 16, 2014
    Applicant: University of Houston System
    Inventors: Shoujun XU, Li YAO, Yuhong WANG, Qiongzheng HU, Haopeng YANG