Patents by Inventor Qirui Hu

Qirui Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of culturing retinal pigmented epithelium cells, including Xeno-free production, RPE enrichment, and cryopreservation
    Patent number: 10246682
    Abstract: The production of high quality retinal pigmented epithelium (RPE) cells is necessary for research and potential therapeutic uses. Especially desirable are methods for the production of RPE cells using xeno-free culture conditions. Disclosed herein are novel methods for the production of RPE cells from pluripotent cells with high yields, including xeno-free production methods. Also provided are methods of efficiently isolating RPE cells from cultures containing heterogeneous cell types, allowing for substantially pure RPE cell cultures to be established. Additionally, novel methods for the cryopreservation of RPE cells are provided.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: April 2, 2019
    Assignees: The Regents of the University of California, University of Southern California
    Inventors: Dennis Clegg, Sherry T. Hikita, Lincoln V. Johnson, Liane Miller, Marlene Tsie, Chelsea D. Presbrey, Lisa R. Conti, Michelle A. Maloney, David R. Hinton, Qirui Hu
  • Methods of Culturing Retinal Pigmented Epithelium Cells, Including Xeno-Free Production, RPE Enrichment, and Cryopreservation
    Publication number: 20180087029
    Abstract: The production of high quality retinal pigmented epithelium (RPE) cells is necessary for research and potential therapeutic uses. Especially desirable are methods for the production of RPE cells using xeno-free culture conditions. Disclosed herein are novel methods for the production of RPE cells from pluripotent cells with high yields, including xeno-free production methods. Also provided are methods of efficiently isolating RPE cells from cultures containing heterogeneous cell types, allowing for substantially pure RPE cell cultures to be established. Additionally, novel methods for the cryopreservation of RPE cells are provided.
    Type: Application
    Filed: November 17, 2017
    Publication date: March 29, 2018
    Inventors: Dennis Clegg, Sherry Hikita, Lincoln Johnson, Liane Miller, Marlene Tsie, Chelsea Presbrey, Lisa Conti, Michelle Maloney, David Hinton, Qirui Hu
  • Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation
    Patent number: 9850463
    Abstract: The production of high quality retinal pigmented epithelium (RPE) cells is necessary for research and potential therapeutic uses. Especially desirable are methods for the production of RPE cells using xeno-free culture conditions. Disclosed herein are novel methods for the production of RPE cells from pluripotent cells with high yields, including xeno-free production methods. Also provided are methods of efficiently isolating RPE cells from cultures containing heterogeneous cell types, allowing for substantially pure RPE cell cultures to be established. Additionally, novel methods for the cryopreservation of RPE cells are provided.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: December 26, 2017
    Assignee: The Regents of the University of California
    Inventors: Sherry Hikita, Dennis Clegg, Lincoln Johnson, Liane Miller, Marlene Tsie, Chelsea Presbrey, Lisa Conti, Michelle Maloney, David Hinton, Qirui Hu