Patents by Inventor Qiu Li

Qiu Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250109146
    Abstract: The present invention discloses a bridged ring-substituted heteroaryl-pyran derivative and a use thereof, and in particular discloses a compound as represented in formula (VI) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 18, 2023
    Publication date: April 3, 2025
    Inventors: Yang ZHANG, Wentao WU, Zhixiang LI, Wenyuan ZHU, Ping YANG, Qiu LI, Jian LI, Shuhui CHEN
  • Publication number: 20250066387
    Abstract: The present application relates to a pyrimidopyran compound, and specifically discloses a compound as represented by formula (III), and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 27, 2022
    Publication date: February 27, 2025
    Applicant: D3 Bio (Wuxi) Co., Ltd.
    Inventors: Yang Zhang, Wentao Wu, Zhixiang Li, Wenyuan Zhu, Ping Yang, Qiu Li, Jian Li, Shuhui Chen
  • Publication number: 20250034099
    Abstract: A class of benzoxazinone derivatives and a preparation method therefor, specifically related to a compound shown in formula (II), or a stereoisomer or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 14, 2022
    Publication date: January 30, 2025
    Applicants: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., MEDSHINE DISCOVERY INC.
    Inventors: Lingyun WU, Zheming XIAO, Yi CHEN, Xiongbin XU, Wei XIA, Tangyang GUO, Lan CAO, Chi-chung CHAN, Qiu LI, Jian LI, Shuhui CHEN
  • Publication number: 20240327433
    Abstract: The present application relates to a pyrimidopyran compound, and specifically discloses a compound as represented by formula (III), and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 27, 2022
    Publication date: October 3, 2024
    Applicant: Medshine Discovery Inc.
    Inventors: Yang Zhang, Wentao Wu, Zhixiang Li, Wenyuan Zuh, Ping Yang, Qiu Li, Jian Li, Shuhui Chen
  • Patent number: 12005784
    Abstract: Disclosed are an electric wheel assembly applicable for a parallelly mounted dual-tire wheel, an axle, and a vehicle. The electric wheel assembly includes a wheel and support axle assembly, an internal-rotor hub motor, a planetary gear reducer and a brake system. A planetary carrier is connected to a hub. The hub is connected to a spoke and a rim. The wheel support axle passes through a rotor sleeve and is provided with a hub bearing to support the hub and a whole wheel. A sun gear disposed at an end of the rotor sleeve of the internal-rotor hub motor is a power input of the planetary gear speed reducer, and the planetary carrier is a power output. A planetary gear of the planetary gear reducer is a tower-shaped gear and realizes a relatively high transmission ratio under a condition that an axial length is relatively small.
    Type: Grant
    Filed: April 4, 2021
    Date of Patent: June 11, 2024
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Jian-Qiu Li, Jia-Yi Hu, Bing-Kun Cai, Hang Li, Liang-Fei Xu, Ming-Gao Ouyang
  • Patent number: 11973248
    Abstract: A method for diagnosing degradation of a fuel cell stack, including: S10, qualitatively determining a degradation type of the fuel cell stack according to a voltage-current curve of the fuel cell stack; S20, quantitatively measuring parameter values of each of individual cells of the fuel cell stack according to the degradation type, and quantitatively determining a degradation degree of each of the individual cells according to the parameter values; S30, determining a uniformity degradation degree among the individual cells of the fuel cell stack according to a non-uniformity degree of a voltage distribution of the individual cells. By qualitatively determining the degradation type of the fuel cell stack, the degradation condition of the entire fuel cell stack may be obtained.
    Type: Grant
    Filed: June 5, 2021
    Date of Patent: April 30, 2024
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Jian-Qiu Li, Zun-Yan Hu, Liang-Fei Xu, Ming-Gao Ouyang
  • Patent number: 11945302
    Abstract: A low-floor electric axle assembly including: an axle housing, two hub motors, two planetary gear reducers, two hubs, a brake system, two C-shaped beams, and a suspension system. Mechanical mounting of the suspension system is compatible with a conventional axle. The axle housing has a left and right symmetrical dumbbell-shaped structure configured to bear a weight of a vehicle. The hub motors are inner rotor type motors and are separately arranged at two ends of the axle housing left and right symmetrically. The hub motors are arranged coaxially with two wheels respectively. Two hub motor rotors are connected to the planetary gear reducers respectively. Each of the planetary gear reducers is a single-stage planetary gear reducer. A sun gear of each of the planetary gear reducers receives power outputted by each of the hub motor. Two planetary gear reducer housings are power output ends connected to two rims respectively.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: April 2, 2024
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Jian-Qiu Li, Jia-Yi Hu, Liang-Fei Xu, Bing-Kun Cai, Hang Li
  • Publication number: 20240043386
    Abstract: The present invention provides for compounds of Formula (I) wherein R1 has any of the values defined in the specification, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
    Type: Application
    Filed: October 10, 2023
    Publication date: February 8, 2024
    Inventors: Andrew Bogdan, David J. Hardee, Timothy R. Hodges, Henry Korman, Huan-Qiu Li, Michael R. Schrimpf
  • Publication number: 20230357248
    Abstract: Disclosed are a pyrrolopyrimidine compound and a use thereof in preparing a medicine for diseases related to a BTK protein kinase inhibitor. Specially, disclosed are a compound as shown in formula (III) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 13, 2020
    Publication date: November 9, 2023
    Inventors: Yang ZHANG, Wentao WU, Kaijun GENG, Qiu LI, Jian LI, Shuhui CHEN
  • Publication number: 20230116732
    Abstract: A loading/unloading system for a quay type full-automatic container terminal includes a plurality of shore cranes, an operation lane area between two rails of the shore cranes, an operation area from a rear side of a landside rail of the shore cranes to a yard, an automatic container yard area, an operation lane area of the yard, and facilities behind the yard. The shore cranes are disposed in parallel at a front edge of a container terminal to autonomously complete shipping and unshipping operations of containers, and autonomously complete loading/unloading processes of artificial intelligence transportation robots through information interaction with an artificial intelligence transportation robot system. The operation lane area between two rails of the shore cranes includes: a lambdoidal reverse operation area of inner container trucks, a ship lofting operation area, and a loading/unloading operation area of the inner container trucks, which are physically isolated by fences.
    Type: Application
    Filed: October 7, 2022
    Publication date: April 13, 2023
    Inventors: Bin CHU, Guangjun JIAO, Jiemin YANG, Rong YANG, Yanhui GAO, Pei CHEN, Kai ZHANG, Bin WU, Xiwang LIU, Hao CHAI, Xichao KONG, Miao FENG, Pai PENG, Qiu LI
  • Publication number: 20230072997
    Abstract: The disclosure provides an intelligent horizontal transportation system for a completely automatic side-loading/unloading container terminal. The system includes a horizontal transportation device including an unmanned artificial intelligence robot of transportation (ART) and a horizontal transportation control system that intelligently manages and controls the ART to enable it to complete horizontal transportation. The horizontal transportation control system is in real-time connection and communication with a terminal operation system (TOS), an automatic field crane, an automatic shore crane and the ART to complete information interactive processing to realize information interconnection, so as to guarantee real-time utilization of information and intelligent control of the ART. The horizontal transportation control system realizes intelligent management and control of the horizontal transportation device by executing the following functions.
    Type: Application
    Filed: September 8, 2022
    Publication date: March 9, 2023
    Inventors: Bin CHU, Guangjun JIAO, Jiemin YANG, Rong YANG, Yanhui GAO, Pei CHEN, Bin WU, Kai ZHANG, Xiwang LIU, Weiyu NING, Jiawei TANG, Miao FENG, Pai PENG, Qiu LI
  • Publication number: 20230002410
    Abstract: Disclosed are a class of compounds having a highly selective inhibition of ROS1, and the use thereof in the preparation of drugs for treating diseases related to abnormal ROS1 kinase expression. Specifically disclosed are compounds represented by formula (IV) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 18, 2020
    Publication date: January 5, 2023
    Inventors: Jianfei WANG, Guangwen YANG, Jikui SUN, Zhihua AO, Peng LI, Yang ZHANG, Qiu LI, Jian LI, Shuhui CHEN
  • Publication number: 20220213041
    Abstract: The present invention provides for compounds of Formula (I) wherein R1 has any of the values defined in the specification, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
    Type: Application
    Filed: December 17, 2021
    Publication date: July 7, 2022
    Applicant: AbbVie Global Enterprises Ltd.
    Inventors: Andrew Bogdan, David J. Hardee, Timothy R. Hodges, Henry Korman, Huan-Qiu Li, Michael R. Schrimpf
  • Patent number: 11309559
    Abstract: A multi-environment integrative thermal management method for a fuel cell vehicle is provided. The method can ensure the accuracy and the stability of the control for a temperature of a fuel cell system of the fuel cell vehicle in a complicated and changeable environment, decrease the energy consumption of the entire vehicle, and increase the economical efficiency of the entire vehicle.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: April 19, 2022
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Jian-Qiu Li, Hui-Ze Liu, Liang-Fei Xu, Zun-Yan Hu, Ming-Gao Ouyang
  • Patent number: 11236094
    Abstract: Provided is a FGFR inhibitor, designating a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. Also provided is the application of a drug for treating solid tumors, such as FGFR related diseases.
    Type: Grant
    Filed: August 15, 2018
    Date of Patent: February 1, 2022
    Assignee: CSPC ZHONGQI PHARMACEUTICALL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Yikai Wang, Yang Zhang, Zhengxia Chen, Linlin Chen, Tao Feng, Rongxin Huang, Qiu Li, Deyao Li, Jikui Sun, Yangyang Xu, Jie Li, Jian Li, Shuhui Chen
  • Publication number: 20220029182
    Abstract: A multi-environment integrative thermal management method for a fuel cell vehicle is provided. The method can ensure the accuracy and the stability of the control for a temperature of a fuel cell system of the fuel cell vehicle in a complicated and changeable environment, decrease the energy consumption of the entire vehicle, and increase the economical efficiency of the entire vehicle.
    Type: Application
    Filed: October 6, 2021
    Publication date: January 27, 2022
    Inventors: JIAN-QIU LI, HUI-ZE LIU, LIANG-FEI XU, ZUN-YAN HU, MING-GAO OUYANG
  • Publication number: 20210305597
    Abstract: Disclosed are a gas sampling system and a gas sampling method for a fuel cell, a current density distribution estimation method for the fuel cell, a calibration method and a calibration device for an internal state model for the fuel cell, and a computer equipment. The gas sampling method for a fuel cell includes arranging a plurality of sampling pipelines and a plurality of sampling points, the plurality of sampling points being arranged at a cathode inlet, an anode outlet, an anode inlet, a cathode outlet, and in an anode flow channel, and a cathode flow channel of the fuel cell, the sampling points arranged in the anode flow channel and the cathode flow channel being located in central regions of cross sections of the flow channels, and the sampling pipelines being connected to the plurality of sampling points, respectively, and configured to guide gas inside the fuel cell out.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 30, 2021
    Inventors: JIAN-QIU LI, QING WANG, LIANG-FEI XU, CHUAN FANG, ZUN-YAN HU, HONG-LIANG JIANG, MING-GAO OUYANG
  • Publication number: 20210296660
    Abstract: The present disclosure relates to a fuel cell bipolar plate including a substrate. A surface of the substrate defines a first flow channel and a second flow channel adjacent to the first flow channel. A rib is formed between the first flow channel and the second flow channel. A top surface of the rib defines a groove or a second bore. One or both of the first flow channel and the second flow channel is in fluid communication with the groove or the second bore.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 23, 2021
    Inventors: ZUN-YAN HU, JIAN-QIU LI, LIANG-FEI XU, HUI-ZE LIU, LING XU, MING-GAO OUYANG
  • Publication number: 20210296661
    Abstract: The present disclosure relates to a fuel cell stack, a bipolar plate, and a gas diffusion layer. The fuel cell stack includes a plurality of first graphite bipolar plates, a plurality of second graphite bipolar plates, and a plurality of reacting units arranged in sequence. The first graphite bipolar plate includes an air flow channel, a hydrogen gas flow channel, and a cooling flow channel. At least one second graphite bipolar plate is disposed between two adjacent first graphite bipolar plates. The second graphite bipolar plate includes an air flow channel and a hydrogen gas flow channel. A reacting unit is disposed between any two adjacent bipolar plates.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 23, 2021
    Inventors: LING XU, JIAN-QIU LI, LIANG-FEI XU, ZUN-YAN HU, HUI-ZE LIU, ZHI-NA WANG, MING-GAO OUYANG
  • Publication number: 20210296668
    Abstract: A method for diagnosing degradation of a fuel cell stack, including: S10, qualitatively determining a degradation type of the fuel cell stack according to a voltage-current curve of the fuel cell stack; S20, quantitatively measuring parameter values of each of individual cells of the fuel cell stack according to the degradation type, and quantitatively determining a degradation degree of each of the individual cells according to the parameter values; S30, determining a uniformity degradation degree among the individual cells of the fuel cell stack according to a non-uniformity degree of a voltage distribution of the individual cells. By qualitatively determining the degradation type of the fuel cell stack, the degradation condition of the entire fuel cell stack may be obtained.
    Type: Application
    Filed: June 5, 2021
    Publication date: September 23, 2021
    Inventors: JIAN-QIU LI, ZUN-YAN HU, LIANG-FEI XU, MING-GAO OUYANG