Abstract: Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X—Z-A? wherein one of either A or A? comprises a luminescent chelate and the other one of A or A? comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.

Abstract: Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X—Z-A? wherein one of either A or A? comprises a luminescent chelate and the other one of A or A? comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.

Abstract: This invention concerns a bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), wherein free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Furthermore, the invention concerns a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.

Abstract: A bottom body of a footwear object with a footwear body, comprising an outsole layer defining a bottom surface which is adapted for having direct contact with the ground and a connecting surface opposite to the bottom surface arranged for connecting to the footwear body; and a fabric unit integrally provided on the bottom surface of the outsole layer which defines a fabric portion, whereby the fabric unit is capable of providing abrasion resistance in both smooth and oil-containing ground surface. the fabric unit is made of fabric materials which is capable of providing abrasion resistance in oil-containing ground surface. comprises a plurality of fabric members spacedly provided on the bottom surface of the outsole layer forming a predetermined pattern on the bottom surface.

Abstract: This invention concerns a bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), wherein free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Furthermore, the invention concerns a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.

Abstract: A bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), where free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Also disclosed is a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.

Abstract: Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X-Z-A? wherein one of either A or A? comprises a luminescent chelate and the other one of A or A? comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.

Abstract: A utility knife having a handle and a blade holder which is pivotally mounted on the handle for movement from an unfolded position to a folded position. The handle has a space adapted to receive the blade holder when the blade holder is in its folded position. A spring pressed lock plug is provided to move into and out of the space to hold the blade holder in the folded and unfolded positions. The blade holder includes a main wall and guard wall pivotally mounted on the main wall to pivot from an open position to a closed position overlying the main wall. The main wall being adapted to hold a blade so that a blade is interposed between the main wall and guard wall when the guard wall is in its closed position.

Abstract: A bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), where free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Also disclosed is a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.

Abstract: A hack saw having a blade holding assembly and a blade lock assembly. The blade lock assembly having moveable blade lock means adapted to receive a blade therebetween, mechanism for moving the blade lock means to a position to hold a blade in place.

Abstract: A utility knife comprising a casing, a blade holder moveably mounted within the casing, said blade holder being moveable incrementally from a fully extended position outside the casing to a fully retracted position inside the casing whereby the blade holder may be positioned in a partially extended position.

Abstract: A knife having a handle with a pair of ends and a knife assembly pivotally mounted on each end for movement from a folded to an unfolded position. The handle has a space adapted to receive the knife assemblies when the knife assemblies are in the folded positions. Each knife assembly having a blade at one end and tang at the other end with the tang having a lock edge. A lock sleeve is mounted within the handle and has a body and a pair of spring lock fingers which are biased in opposite directions away from the plane of the body of the lock sleeve. Each of the spring lock fingers has a lock shoulder adapted to cooperate with the lock edge of said knife assemblies when the knife assemblies are in their unfolded position to at least assist to hold the knife assemblies in their unfolded position.

Abstract: A bar clamp having a first jaw assembly, a second jaw assembly and a bar. The first and second jaw assemblies are mounted on the bar which is movable relative to the second jaw assembly. A trigger is operatively associated with the bar and is adapted to be activated to move the bar and the first jaw assembly relative to the second jaw assembly in one direction. A release mechanism on the second jaw assembly is operatively associated with the bar and is adapted to be activated in order to permit the bar and the first jaw assembly to move relative to the second jaw assembly in the opposite direction.

Abstract: A driver tool having a hollow handle and a head. The head has a body portion and a mouth portion. A plurality of channels formed in body portion each of which is adapted to receive a driver. A selector assembly is mounted within body portion and comprises an exit groove and a stop gate located between said mouth portion and the channels. An exit notch is provided in the stop gate which communicates with the exit groove. Rotation of the selector assembly relative to the handle to move the exit groove and the exit notch past the channels so that when the rotation is stopped when the exit groove and the exit notch are opposite a predetermined channel permits a driver in that channel may move from the channel into the exit groove through the exit notch and thereby freeing a driver in the exit groove to move out of the exit groove through the mouth portion and to protrude out of the handle assembly to an extended position.

Abstract: A utility knife having a handle and a blade holder which is pivotally mounted on the handle for movement from an unfolded position to a folded position. The handle has a space adapted to receive the blade holder when the blade holder is in its folded position. The blade holder includes a main wall and guard wall mounted together and adapted to receive a blade therebetween and a locking pivotally mounted on the blade holder to lock the blade in place.