Abstract: The present disclosure provides a refrigerator with a lifting shelf, including a lifting shelf, a shelf driving mechanism, and a shelf stroke detection device. The shelf driving mechanism includes: a driving motor and a gear transmission mechanism, where the gear transmission mechanism includes at least one group of transmission gears, the driving motor outputs a torque through a driving output shaft, and a first pulley is disposed on the driving output shaft; a guide rail slidably connected to a support piece on the guide rail, wherein the lifting shelf is fixedly connected with the support piece; and a traction cable, where the traction cable is wound around the first pulley, and the other end of the traction cable is fixedly connected with the support piece.

Abstract: The present disclosure provides a refrigerator with a lifting shelf, including a lifting shelf, a shelf driving mechanism, and a shelf stroke detection device. The shelf driving mechanism includes: a driving motor and a gear transmission mechanism, where the gear transmission mechanism includes at least one group of transmission gears, the driving motor outputs a torque through a driving output shaft, and a first pulley is disposed on the driving output shaft; a guide rail slidably connected to a support piece on the guide rail, wherein the lifting shelf is fixedly connected with the support piece; and a traction cable, where the traction cable is wound around the first pulley, and the other end of the traction cable is fixedly connected with the support piece.

Abstract: The invention provides a high-throughput screening system based on multi-manipulators, and belongs to the field of biotechnology and detection equipment. A high-throughput screening system based on multi-manipulators, comprises of the first manipulator, sampler, pipette, plate washer, microplate reader, the second manipulator, centrifuge, deep-well plate library, waste shallow-well plate barrel, shallow-well plate library, waste needle plate barrel, needle library, waste deep-well plate barrel, collection box. The present invention is a combination of microbiology and mechanics. The aim of the invention is to realize the automation and intelligentization of the high throughput screening experiment, effectively improve the experimental accuracy, reliability and efficiency. It contributes to the development of high throughput screening technology for microorganisms and drugs.

Abstract: An exosome active formulation for inhibiting endothelial cell migration, and a preparation method and use thereof include the following steps: isolating primary umbilical vein endothelial cells and performing cell culture and passage; adding anisodamine to a culture medium of the subcultured endothelial cells to pretreat the endothelial cells, and then replacing the culture medium with a new endothelial cell culture medium and adding TNF-? to continue the culture of the endothelial cells; extracting exosomes from the TNF-? containing endothelial cell culture medium obtained after the endothelial cells are cultivated; and identifying the exosomes. The exosome active formulation for inhibiting endothelial cell migration prepared by the preparation method of this disclosure and its use in the antitumor drugs.

Abstract: An exosome active formulation for promoting endothelial cell angiogenesis, and a preparation method and use thereof include the following steps: isolating primary umbilical vein endothelial cells and performing cell culture and passage; adding anisodamine to a culture medium of the subcultured endothelial cells to treat the endothelial cells, and then replacing the culture medium with a new endothelial cell culture medium to continue the culture of the endothelial cells; extracting exosomes from the endothelial cell culture medium obtained after the endothelial cells are cultivated; and identifying the exosomes. The exosome active formulation for promoting endothelial cell angiogenesis prepared by the preparation method and its use in the manufacture of a medicament for treating microvascular injury, microcirculation dysfunction and cardio-cerebral infarction.

Abstract: An exosome active formulation for inhibiting endothelial cell migration, and a preparation method and use thereof include the following steps: isolating primary umbilical vein endothelial cells and performing cell culture and passage; adding anisodamine to a culture medium of the subcultured endothelial cells to pretreat the endothelial cells, and then replacing the culture medium with a new endothelial cell culture medium and adding TNF-? to continue the culture of the endothelial cells; extracting exosomes from the TNF-? containing endothelial cell culture medium obtained after the endothelial cells are cultivated; and identifying the exosomes. The exosome active formulation for inhibiting endothelial cell migration prepared by the preparation method of this disclosure and its use in the antitumor drugs.

Abstract: An exosome active formulation for promoting endothelial cell angiogenesis, and a preparation method and use thereof include the following steps: isolating primary umbilical vein endothelial cells and performing cell culture and passage; adding anisodamine to a culture medium of the subcultured endothelial cells to treat the endothelial cells, and then replacing the culture medium with a new endothelial cell culture medium to continue the culture of the endothelial cells; extracting exosomes from the endothelial cell culture medium obtained after the endothelial cells are cultivated; and identifying the exosomes. The exosome active formulation for promoting endothelial cell angiogenesis prepared by the preparation method and its use in the manufacture of a medicament for treating microvascular injury, microcirculation dysfunction and cardio-cerebral infarction.

Abstract: The present invention provides a production-line-type high-throughput screening system, which relates to the field of biotechnology and testing equipment. The system comprises of four manipulators, three parallel conveyor belts with fixed slots, 2-DOF slipway and fixed fixtures, 96-channel pipetting system, coloring device, oscillating mixing device, microplate reader, well plates loading platform and well plates recycling platform. Manual operation takes five minutes to detect one 96-well plate, while this system can handle 20 96-well plates per minute. It expands the number of screening targets, making the screening process more clearly and concisely and liberating manual labor. The system makes effective contributions to the development of microbial breeding technology.

Abstract: The invention provides a high-throughput screening system based on multi-manipulators, and belongs to the field of biotechnology and detection equipment. A high-throughput screening system based on multi-manipulators, comprises of the first manipulator, sampler, pipette, plate washer, microplate reader, the second manipulator, centrifuge, deep-well plate library, waste shallow-well plate barrel, shallow-well plate library, waste needle plate barrel, needle library, waste deep-well plate barrel, collection box. The present invention is a combination of microbiology and mechanics. The aim of the invention is to realize the automation and intelligentization of the high throughput screening experiment, effectively improve the experimental accuracy, reliability and efficiency. It contributes to the development of high throughput screening technology for microorganisms and drugs.

Abstract: The present invention provides a production-line-type high-throughput screening system, which relates to the field of biotechnology and testing equipment. The system comprises of four manipulators, three parallel conveyor belts with fixed slots, 2-DOF slipway and fixed fixtures, 96-channel pipetting system, coloring device, oscillating mixing device, microplate reader, well plates loading platform and well plates recycling platform. Manual operation takes five minutes to detect one 96-well plate, while this system can handle 20 96-well plates per minute. It expands the number of screening targets, making the screening process more clearly and concisely and liberating manual labor. The system makes effective contributions to the development of microbial breeding technology.

Abstract: The invention provides a high-throughput screening system based on a single manipulator, and belongs to the field of biotechnology and detection equipment. A high-throughput screening system based on single manipulator, comprises of one manipulator which is surrounded by deep well plate loading platform, shallow well plate loading platform, pipetting head loading platform, control cabinet, waste pipetting heads container platform, shallow well plate recycling platform, deep well plate recycling platform, Microplate Reader with oscillating mixer and items-placing platform in a counterclockwise or clockwise order. The present invention is a combination of microbiology and mechanics. It promotes the automation of microbial high-throughput screening system for screening microorganisms with specific properties. It effectively contributes to the development of microbial breeding technology and further promotes the development of microbial science.

Abstract: The invention relates to an elastic corrugated pipe single-acting cylinder-driven mechanical gripper with a series-connection plate spring framework. The mechanical gripper consists of a palm and two flexible fingers or a palm and three flexible fingers. The flexible fingers are identical in structure. Each flexible finger consists of an elastic corrugated pipe single-acting cylinder and a series-connection plate spring. Dimensions of all plate springs connected in series are optimally designed according to grasping objects. The mechanical gripper is driven by the elastic corrugated pipe single-acting cylinder to generate a grasping force. The mechanical gripper applies to the grasping of fragile, brittle objects or the grasping of objects varying with shapes and dimensions. When connected with a robot body, the mechanical gripper particularly applies to the production and logistic fields for grasping, sorting and packing of foods, agriculture products and light industrial products.

Abstract: The invention relates to an elastic corrugated pipe single-acting cylinder-driven mechanical gripper with a series-connection plate spring framework. The mechanical gripper consists of a palm and two flexible fingers or a palm and three flexible fingers. The flexible fingers are identical in structure. Each flexible finger consists of an elastic corrugated pipe single-acting cylinder and a series-connection plate spring. Dimensions of all plate springs connected in series are optimally designed according to grasping objects. The mechanical gripper is driven by the elastic corrugated pipe single-acting cylinder to generate a grasping force. The mechanical gripper applies to the grasping of fragile, brittle objects or the grasping of objects varying with shapes and dimensions. When connected with a robot body, the mechanical gripper particularly applies to the production and logistic fields for grasping, sorting and packing of foods, agriculture products and light industrial products.