Patents by Inventor Qiu-Ping Qin

Qiu-Ping Qin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thrombin Substrate and Assay for Determining the Level of Bioactive Thrombin in a Sample
    Publication number: 20130344520
    Abstract: Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X—Z-A? wherein one of either A or A? comprises a luminescent chelate and the other one of A or A? comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.
    Type: Application
    Filed: August 26, 2013
    Publication date: December 26, 2013
    Applicant: Radiometer Medical APS
    Inventors: Qiu-Ping Qin, Harri TAKALO, Allan Milton BYRNARD, Kirsten Marie JAKOBSEN
  • Thrombin substrate and assay for determining the level of bioactive thrombin in a sample
    Patent number: 8535898
    Abstract: Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X—Z-A? wherein one of either A or A? comprises a luminescent chelate and the other one of A or A? comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: September 17, 2013
    Assignee: Radiometer Medical APS
    Inventors: Qiu-Ping Qin, Harri Takalo, Allan Milton Byrnard, Kirsten Marie Jakobsen
  • METHOD FOR DIAGNOSING ACUTE CORONARY SYNDROME
    Publication number: 20120264139
    Abstract: This invention concerns a bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), wherein free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Furthermore, the invention concerns a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.
    Type: Application
    Filed: June 28, 2012
    Publication date: October 18, 2012
    Inventors: Qiu-Ping Qin, Kim Pettersson
  • METHOD FOR DIAGNOSING ACUTE CORONARY SYNDROME
    Publication number: 20110014631
    Abstract: This invention concerns a bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), wherein free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Furthermore, the invention concerns a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.
    Type: Application
    Filed: September 27, 2010
    Publication date: January 20, 2011
    Inventors: Qiu-Ping QIN, Kimu Pettersson
  • Method for diagnosing acute coronary syndrome
    Patent number: 7824876
    Abstract: A bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), where free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Also disclosed is a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: November 2, 2010
    Assignee: Turun Yliopisto
    Inventors: Qiu-Ping Qin, Kim Pettersson
  • Thrombin Substrate and Assay for Determining the Level of Bioactive Thrombin in a Sample
    Publication number: 20100184106
    Abstract: Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X-Z-A? wherein one of either A or A? comprises a luminescent chelate and the other one of A or A? comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.
    Type: Application
    Filed: July 15, 2009
    Publication date: July 22, 2010
    Applicant: Radiometer Medical ApS
    Inventors: Qiu-Ping Qin, Harri Takalo, Allan Milton Byrnard, Kirsten Marie Jakobsen
  • Method for diagnosing acute coronary syndrome
    Publication number: 20070111254
    Abstract: A bioaffinity assay for quantitative determination in a sample of free PAPP-A, defined as the pregnancy associated plasma protein A (PAPP-A) that is not complexed to the proform of major basic protein (proMBP), where free PAPP-A is determined either i) as a calculated difference between measured total PAPP-A and measured PAPP-A complexed to proMBP, or ii) by a direct bioaffinity assay measuring only free PAPP-A. Also disclosed is a method for diagnosing an acute coronary syndrome in a person by using as marker either free PAPP-A as such or a ratio free PAPP-A/total PAPP-A, free PAPP-A/PAPP-A complexed to proMBP, or PAPP-A complexed to proMBP/total PAPP-A.
    Type: Application
    Filed: January 19, 2005
    Publication date: May 17, 2007
    Inventors: Qiu-Ping Qin, Kim Pettersson