Abstract: An iontophoretic transdermal drug delivery system that utilizes a porous conductive polyaniline membrane as one of two electrodes, with both electrodes in contact with an aqueous solution of the ingredient in ionic and nonionic form, and the membrane additionally in contact with the skin surface of the mammal. Upon providing the appropriate direct current flow by voltage generating means through the electrodes and solution, the ingredient is caused to pass through the porous membrane and be released in ionic form through the skin surface of the mammal.

Abstract: The present disclosure is directed to iontophoretic transdermal drug delivery (TDD) systems for pharmaceutically active ingredients and methods of using the same in administration of such ingredients to mammals. More specifically, the TDD system utilizes a porous conductive polyaniline membrane as one of two electrodes, with both electrodes in contact with an aqueous solution of the ingredient in ionic and nonionic form, and the membrane additionally in contact with the skin surface of the mammal. Upon providing the appropriate direct current flow by voltage generating means through the electrodes and solution, the ingredient is caused to pass through the porous membrane and be released in ionic form through the skin surface of the mammal.