Patents by Inventor Qiuxiang Zhang

Qiuxiang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250127832
    Abstract: Disclosed is a Lactobacillus plantarum and an application thereof in the production of urolithin A, belonging to the technical field of biology. The disclosure provides a Lactiplantibacillus plantarum CCFM1290 preserved in Guangdong Microbial Culture Collection Center (GDMCC) with a preservation number of GDMCC No: 62801 and a preservation date of Sep. 15, 2022. The L. plantarum CCFM1290 may convert ETs into various Uros represented by Uro-A. A fermented product or compound preparation provided by the disclosure may relieve muscle function damage. Compared with a control group, the fermented product and compound preparation may improve the swimming capability of Caenorhabditis elegans by 33.84% and 27.99%. Finally, Uro-type substances such as Uro-A obtained by this biosynthesis method may be applied to functional food development to achieve beneficial effects of delaying senescence, keeping muscles healthy, etc.
    Type: Application
    Filed: December 20, 2024
    Publication date: April 24, 2025
    Inventors: Shumao CUI, Xin TANG, Mengwei ZHANG, Bingyong MAO, Qiuxiang Zhang, Bo YANG, Jianxin ZHAO, Wei CHEN
  • Publication number: 20240374660
    Abstract: The present disclosure relates to a Bifidobacterium longum CCFM1206 capable of producing sulforaphane and relieving inflammation, and belongs to the field of microbial technology. B. longum CCFM1206 provided by the present disclosure can convert glucoraphanin to sulforaphane, promoting the metabolism of glucoraphanin and the generation of sulforaphane in mammals. The B. longum CCFM1206 according to the present disclosure can be used alone or in combination with glucoraphanin to relieve weight loss during ulcerative colitis, reduce the release of pro-inflammatory factors from the colon, improve the colonic barrier function, relieve the splenomegaly due to systemic inflammation, reduce the levels of pro-inflammatory factors in the serum, reduce the levels of pro-inflammatory factors in the liver tissues and increase the levels of anti-inflammatory factors, and increase the levels of short-chain fatty acids.
    Type: Application
    Filed: July 23, 2024
    Publication date: November 14, 2024
    Inventors: Bingyong MAO, Jiaying Wu, Shumao Cui, Xin Tang, Qiuxiang Zhang, Jianxin Zhao, Wei Chen
  • Publication number: 20240277784
    Abstract: The present disclosure discloses a strain of highly organic zinc-enriched Bifidobacterium animalis capable of promoting growth and reproductive development, belonging to the technical field of microorganisms. The B. animalis CCFM1230 screened by the present disclosure can efficiently enrich inorganic zinc and convert same into organic zinc, which is better absorbed and utilized by organisms, and effectively promotes growth and reproductive development. Animal experiments have proved that zinc-rich B. animalis can promote the growth and reproductive development of male rat pups, exert higher biological activity than inorganic zinc, and meet the physiological requirements of zinc supplementation. According to the present disclosure, the B. animalis CCFM1230 can efficiently enrich inorganic zinc for the preparation of a probiotic preparation capable of promoting growth and reproductive development, and thus has great application prospects in the field of food or medicine.
    Type: Application
    Filed: April 30, 2024
    Publication date: August 22, 2024
    Inventors: Bingyong MAO, Shumao Cui, Xinran Han, Xin Tang, Qiuxiang Zhang, Jianxin Zhao, Wei Chen
  • Publication number: 20240260144
    Abstract: A transparent structure comprising a transparent substrate, a transparent resistive heating element mounted on the substrate, metal traces forming electrodes arranged to be in electrical contact with the transparent heating element and positioned around boundaries of a heated region defining a circuit for electrical flow through the transparent resistive heating element, and a power source connected to the electrodes with the capability of delivering at least 1 volts to the electrodes wherein the transparent resistive heating element comprises a sparse metal conductive layer comprising nanowire segments of noble metal coated silver having a sheet resistance from about 1 Ohms/sq. to about 300 Ohms/sq and having an unpatterned area of at least about 0.25 cm2.
    Type: Application
    Filed: January 25, 2024
    Publication date: August 1, 2024
    Inventors: Xiaofeng Chen, Michael Fang, Yadong Cao, Alexander Seung-il Hong, Xiqiang Yang, Ajay Virkar, Devika Madan Oak, Feiqun Li, Qiuxiang Zhang
  • Publication number: 20230082296
    Abstract: The present disclosure discloses a strain of Lactobacillus fermentum capable of preventing and/or treating periodontitis and an application thereof, belonging to the field of microbiology technology. The present disclosure has screened to obtain a strain of L. fermentum CCFM1139. The L. fermentum CCFM1139 can alleviate periodontitis by inhibiting formation of mixed bacterial biofilms of Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum, thereby reducing the amount of biofilm by 52.45%, and can reduce the content of TNF-? from 131.37 pg/mL to 83.31 pg/mL and IL-8 from 147.70 pg/mL to 121.12 pg/mL in a periodontitis cell model, reduce colonization of the P. gingivalis and the F. nucleatum in the oral cavity by 1-2 orders of magnitude, and reduce the amount of the alveolar bone resorption from 1838.0 ?m to 805.7 ?m.
    Type: Application
    Filed: October 27, 2022
    Publication date: March 16, 2023
    Inventors: Wei CHEN, Qiuxiang Zhang, Wanqing Xu, Wenwei Lu, Hao Zhang, Jianxin Zhao
  • Patent number: 9649347
    Abstract: An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: May 16, 2017
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Wei Chen, Fengwei Tian, Wenli Huang, Jianxin Zhao, Hao Zhang, Gang Wang, Qiuxiang Zhang, Xiaoming Liu, Daming Fan, Feifei Chi
  • Patent number: 9451781
    Abstract: The invention provides a novel strain of cadmium-removing Lactobacillus plantarum bacterium, CCFM8610, which has a good tolerance to acidic environments. Lactobacillus plantarum CCFM8610 has a good tolerance to cadmium-containing medium and can effectively bind cadmium in vitro. Animal studies have shown that it can effectively reduce tissue cadmium accumulation and facilitate fecal cadmium excretion. Lactobacillus plantarum CCFM8610 has a great potential to be used as an active ingredient in cadmium-removing pharmaceutical drugs and fermented foods.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: September 27, 2016
    Assignee: Jiangnan University
    Inventors: Wei Chen, Fengwei Tian, Qixiao Zhai, Gang Wang, Xiaoming Liu, Qiuxiang Zhang, Daming Fan, Jianxin Zhao, Hao Zhang
  • Publication number: 20160113975
    Abstract: An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
    Type: Application
    Filed: December 28, 2015
    Publication date: April 28, 2016
    Applicant: Jiangnan University
    Inventors: Wei Chen, Fengwei Tian, Wenli Huang, Jianxi n Zhao, Hao Zhang, Gang Wang, Qiuxiang Zhang, Xiaoming Liu, Daming Fan, Feifei Chi
  • Patent number: 9320766
    Abstract: The Lactobacillus plantarum CCFM8661 is tolerant to acid and lead ions in vitro which can tolerate lead ions solution with the initial concentration of 150 mg/L, and has a strong capability of binding lead ions, which can reduce the lead level in mice blood, liver, kidney and stomach, significantly improve antioxidant indicators and alleviate pathological symptoms of lead exposed mice.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: April 26, 2016
    Assignee: Jiangnan University
    Inventors: Fengwei Tian, Wei Chen, Qixiao Zhai, Hao Zhang, Jianxin Zhao, Gang Wang, Yuanda Song, Qiuxiang Zhang, Xiaoming Liu, Min Guo, Daming Fan
  • Publication number: 20150272438
    Abstract: Disclosed are various embodiments for imaging retinal intrinsic optical signals (IOS) in vivo. According to various embodiments, imaging retinal intrinsic optical signals (IOS) may comprise illuminating a host retina with near infrared light (NIR) during a test period, wherein the host retina is continuously illuminated by the NIR light during the test period. Sequentially a host retina may be stimulated with a timed bursts of visible light during the test period. A series of images of the retina may be recorded with a line-scan CCD camera and the images may be processed to produce images of intrinsic optical signals (IOS) from retinal photoreceptor cells identified in the images.
    Type: Application
    Filed: October 24, 2013
    Publication date: October 1, 2015
    Applicant: The UAB RESEARCH FOUNDATION
    Inventors: Xincheng Yao, Qiuxiang Zhang, Rongwen Lu
  • Publication number: 20140369981
    Abstract: The Lactobacillus plantarum CCFM8661 is tolerant to acid and lead ions in vitro which can tolerate lead ions solution with the initial concentration of 150 mg/L, and has a strong capability of binding lead ions, which can reduce the lead level in mice blood, liver, kidney and stomach, significantly improve antioxidant indicators and alleviate pathological symptoms of lead exposed mice.
    Type: Application
    Filed: July 18, 2012
    Publication date: December 18, 2014
    Applicant: Jiangnan University
    Inventors: Fengwei Tian, Wei Chen, Qixiao Zhai, Hao Zhang, Jianxin Zhao, Gang Wang, Yuanda Song, Qiuxiang Zhang, Xiaoming Liu, Min Guo, Daming Fan
  • Publication number: 20140363501
    Abstract: An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
    Type: Application
    Filed: July 19, 2012
    Publication date: December 11, 2014
    Applicant: Jiangnan University
    Inventors: Wei Chen, Fengwei Tian, Wenli Huang, Jianxi n Zhao, Hao Zhang, Gang Wang, Qiuxiang Zhang, Xiaoming Liu, Daming Fan, Feifei Chi
  • Publication number: 20140341873
    Abstract: The invention provides a novel strain of cadmium-removing Lactobacillus plantarum bacterium, CCFM8610, which has a good tolerance to acidic environments. Lactobacillus plantarum CCFM8610 has a good tolerance to cadmium-containing medium and can effectively bind cadmium in vitro. Animal studies have shown that it can effectively reduce tissue cadmium accumulation and facilitate fecal cadmium excretion. Lactobacillus plantarum CCFM8610 has a great potential to be used as an active ingredient in cadmium-removing pharmaceutical drugs and fermented foods.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 20, 2014
    Inventors: Wei Chen, Fengwei Tian, Qixiao Zhai, Gang Wang, Xiaoming Liu, Qiuxiang Zhang, Daming Fan, Jianxin Zhao, Hao Zhang