Abstract: A device and methods for producing microneedles includes a microneedle female mold, a vacuum chamber, a filling mechanism and an evacuation mechanism. The vacuum chamber includes a feeding cavity, a filling cavity and a discharging cavity, which are independent of one another. The feeding cavity receives the microneedle female mold therein in non-negative pressure state, and the evacuation mechanism evacuates the feeding cavity that has received the microneedle female mold therein. The filling cavity receives, in negative pressure state, the microneedle female mold transported from the feeding cavity in negative pressure state. The discharging cavity receives, in negative pressure state, the microneedle female mold transported from the filling cavity in negative pressure state and to undergo vacuum destruction after the microneedle female mold is received therein. The device and methods more efficiently produces microneedles in large batches and ensuring formation quality of the produced microneedles.

Abstract: The present invention provides a manufacturing device and a manufacturing method for molds. The manufacturing device includes a molding assembly including a mold table and a male mold. The mold table has an upper surface defining a depression thereon, and the male mold is configured to be disposed on a bottom surface of the depression. A height of the male mold is smaller than a depth of the depression. This manufacturing device can utilize a transfer molding method to manufacture molds in batches with higher mold production efficiency.

Abstract: The present application provides a needle insertion assistant and a medical device including the needle insertion assistant. The needle insertion assistant includes: a housing assembly defining a first inner lumen axially extending therethrough; a pusher assembly disposed within the first inner lumen and including an inner core and an energy storage element, the inner core configured to be axially movable, the energy storage element disposed between the inner core and the housing assembly; and a drive assembly. The needle insertion assistant is configured such that the drive assembly is configured to drive the inner core to move from distal to proximal to cause the energy storage element to store elastic potential energy. The drive assembly is further configured to cause the energy storage element to release the stored elastic potential energy to drive the inner core to move from proximal to distal.

Abstract: A storage rack and a drying device including the storage rack. The storage rack includes a frame and a support beam assembly including a connector seat, a first connector and a support beam. The connector seat is connected to the frame, and the support beam is connected to the connector seat by the first connector. The support beam is connected to the frame by the first connector and the connector seat rather than by direct welding which may cause deformation. It is ensured that the support beam can provide desirable levelness for a shelf panel to be supported thereon. In this way, good levelness of the shelf panel can be achieved at a reduced thickness thereof, resulting in a reduction in economic cost. Moreover, for a detachable shelf panel, its placement and removal can be facilitated.

Abstract: A microneedle casting system includes a vacuum chamber, a motion platform, a first motion assembly, a liquid-filling needle assembly, a second motion assembly, and a controller. The motion platform is arranged in the vacuum chamber; the first motion assembly includes a first transmission component and a first drive component that are connected to each other; the liquid-filling needle assembly includes a liquid-dispensing tip and a liquid-filling needle shaft; the second motion assembly includes a second transmission component and a second drive component which are connected to each other, the liquid-filling needle is connected to the second transmission component, and, driven by the second drive component, the second transmission component drives the liquid-filling needle to move in a second direction; and the first drive component or/and the second drive component are communicatively connected to the controller.

Abstract: A vacuum liquid-filling needle includes a needle shaft (2) and a pressure relief valve (3). The pressure relief valve is disposed within the needle shaft at a first end (21) thereof, and the needle shaft is able to connect at a second end (22) thereof to a pipe for supplying a solution to be filled. The pressure relief valve defines an internal cavity, in which a first slide valve and a second slide valve are disposed so as to be axially spaced apart from each other and both movable relative to the internal cavity. The valve body defines an inflow channel (33), an inflow port (34), an outflow port (35), an outflow channel (37) and exit apertures (38). Each of the inflow channel and the outflow channel is formed by a blind bore, and both the inflow channel and the outflow channel axially extend along the valve body. This vacuum liquid-filling needle can prevent undesired accidental efflux of the solution while providing depressurization and pressure stabilization effects during filling of the solution.

Abstract: An apparatus and method for manufacturing a microneedle are disclosed, which aim to reduce the production costs of microneedle preparation and improve the efficiency and quality of microneedle preparation. The apparatus for manufacturing a microneedle includes a baseplate, an elastomeric female mold, a horizontal movement mechanism, a vertical movement mechanism, a dispenser and a roller mechanism. The elastomeric female mold is disposed on the baseplate and has a surface formed thereon with cavities complementary to needle bodies. The dispenser includes a reservoir for holding a solution for forming the microneedle. The roller mechanism is disposed on the dispenser and includes a roller.