Patents by Inventor Qiuyun WANG

Qiuyun WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hot-forging die with conformal meshy structured cavity surface layer and preparation method thereof
    Patent number: 11465195
    Abstract: The present disclosure discloses a hot-forging die with the conformal meshy structured cavity surface layer and a preparation method thereof. A large-scale hot-forging die includes a die substrate, and a sandwiched layer, a transition layer and a reinforcement layer are formed on the die substrate in sequence. The reinforcement layer and the transition layer are separated into a plurality of small units by the grooves. All the grooves are interconnected and communicated to form a meshy structure. The transition layer grooves are filled with ordinary soft material; the reinforcement layer grooves are filled with high temperature resistant soft material.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: October 11, 2022
    Assignees: CHONGQING JIEPIN TECHNOLOGY CO., LTD, CHONGQING UNIVERSITY
    Inventors: Jiansheng Zhang, Jie Zhou, Yuping Gan, Qian Zhang, Qiuyun Wang, Lvfeng Yang
  • HOT-FORGING DIE WITH CONFORMAL MESHY STRUCTURED CAVITY SURFACE LAYER AND PREPARATION METHOD THEREOF
    Publication number: 20220134411
    Abstract: The present disclosure discloses a hot-forging die with the conformal meshy structured cavity surface layer and a preparation method thereof. A large-scale hot-forging die includes a die substrate, and a sandwiched layer, a transition layer and a reinforcement layer are formed on the die substrate in sequence. The reinforcement layer and the transition layer are separated into a plurality of small units by the grooves. All the grooves are interconnected and communicated to form a meshy structure. The transition layer grooves are filled with ordinary soft material; the reinforcement layer grooves are filled with high temperature resistant soft material.
    Type: Application
    Filed: June 13, 2019
    Publication date: May 5, 2022
    Inventors: Jiansheng ZHANG, Jie ZHOU, Yuping GAN, Qian ZHANG, Qiuyun WANG, Lvfeng YANG
  • Compositions and methods for inhibiting expression of ADAMTS-5 and ADAM17
    Patent number: 10709729
    Abstract: Provided are siRNAs or chemically-modified siRNAs targeted against ADAMTS-5 or ADAM17 for inhibiting the expression of ADAMTS-5 or ADAM17. Use of the siRNAs for treating an ADAMTS-5 or ADAM17 associated disease, such as arthritis and other inflammation-related diseases, by injecting the siRNAs or preparations comprising the siRNAs into an articular cavity of the patient, are also provided.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: July 14, 2020
    Assignees: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES, GUANGZHOU RIBOBIO CO., LTD.
    Inventors: Bill Biliang Zhang, Micky Daniel Tortorella, Zhe Wang, Xiuqun Yang, Qiuyun Wang
  • COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF ADAMTS-5 AND ADAM17
    Publication number: 20180250323
    Abstract: Provided are siRNAs or chemically-modified siRNAs targeted against ADAMTS-5 or ADAM17 for inhibiting the expression of ADAMTS-5 or ADAM17. Use of the siRNAs for treating an ADAMTS-5 or ADAM17 associated disease, such as arthritis and other inflammation-related diseases, by injecting the siRNAs or preparations comprising the siRNAs into an articular cavity of the patient, are also provided.
    Type: Application
    Filed: December 23, 2015
    Publication date: September 6, 2018
    Inventors: Bill Biliang ZHANG, Micky Daniel TORTORELLA, Zhe WANG, Xiuqun YANG, Qiuyun WANG