Patents by Inventor Qiyuan ZHANG

Qiyuan ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • New-type oxazolidinone compounds and preparation method therefor
    Patent number: 12173020
    Abstract: Oxazolidinones having structures represented by structural formula I, preparation methods therefor, and pharmaceutical uses thereof, in particular an application of said compounds and salts or compositions thereof in the treatment of a bacterial infection. In the formula: R1 is a methyl group, an ethyl group, a propyl group, a cyclopropyl group, or a vinyl group; R2 is F; and R3 is F, CH3, C2H5, CF3, CHF2, CH2F, or a cyclopropyl group.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: December 24, 2024
    Assignee: HC SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventors: Cheng Yang, Dongxing Li, Sumin Qi, Qiyuan Zhang, Tieshan Chen, Xiaodan Zhao
  • Thiobenzopyrans and their use in preparation of drugs for treatment of rheumatoid arthritis
    Patent number: 12110282
    Abstract: Provided is a thiobenzopyran-based compound of Formula I and its pharmaceutically acceptable salt, and its use in the preparation of drugs for the treatment of rheumatoid arthritis, wherein X is selected from oxygen, sulfur, —SO—, and —SO2—; Y is a sulfur atom and Z is H, Na, or K. Through preliminary tests of anti-inflammatory activity, compounds of formula I have anti-rheumatoid arthritis effects.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: October 8, 2024
    Assignee: HC SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventors: Cheng Yang, Dongxing Li, Sumin Qi, Qiyuan Zhang, Xiaodan Zhao
  • Expectorant compound, preparation method thereof and use thereof
    Patent number: 11993561
    Abstract: The present disclosure discloses an expectorant compound, and specifically discloses compounds represented by formula I and formula II, pharmaceutically acceptable salts or tautomers thereof.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: May 28, 2024
    Assignee: HC SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventors: Cheng Yang, Sumin Qi, Qiyuan Zhang, Dongxing Li, Tieshan Chen, Xiaodan Zhao
  • THIOBENZOPYRANS AND THEIR USE IN PREPARATION OF DRUGS FOR TREATMENT OF RHEUMATOID ARTHRITIS
    Publication number: 20230242502
    Abstract: Provided is a thiobenzopyran-based compound of Formula I and its pharmaceutically acceptable salt, and its use in the preparation of drugs for the treatment of rheumatoid arthritis, wherein X is selected from oxygen, sulfur, —SO—, and —SO2—; Y is a sulfur atom and Z is H, Na, or K. Through preliminary tests of anti-inflammatory activity, compounds of formula I have anti-rheumatoid arthritis effects.
    Type: Application
    Filed: July 22, 2021
    Publication date: August 3, 2023
    Applicant: HC SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventors: CHENG YANG, DONGXING LI, SUMIN QI, QIYUAN ZHANG, XIAODAN ZHAO
  • NEW-TYPE OXAZOLIDINONE COMPOUNDS AND PREPARATION METHOD THEREFOR
    Publication number: 20230046407
    Abstract: Oxazolidinones having structures represented by structural formula I, preparation methods therefor, and pharmaceutical uses thereof, in particular an application of said compounds and salts or compositions thereof in the treatment of a bacterial infection. In the formula: R1 is a methyl group, an ethyl group, a propyl group, a cyclopropyl group, or a vinyl group; R2 is F; and R3 is F, CH3, C2H5, CF3, CHF2, CH2F, or a cyclopropyl group.
    Type: Application
    Filed: July 1, 2020
    Publication date: February 16, 2023
    Applicant: HC SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventors: CHENG YANG, DONGXING LI, SUMIN QI, QIYUAN ZHANG, TIESHAN CHEN, XIAODAN ZHAO
  • EXPECTORANT COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF
    Publication number: 20220388952
    Abstract: The present disclosure discloses an expectorant compound, and specifically discloses compounds represented by formula I and formula II, pharmaceutically acceptable salts or tautomers thereof.
    Type: Application
    Filed: July 1, 2020
    Publication date: December 8, 2022
    Applicant: HC SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventors: CHENG YANG, SUMIN QI, QIYUAN ZHANG, DONGXING LI, TIESHAN CHEN, XIAODAN ZHAO
  • Voriconazole sodium phosphate hydrates and polymorphs thereof
    Patent number: 9650400
    Abstract: The present invention relates to a voriconazole sodium phosphate hydrate, polymorphs thereof, a preparation method thereof, and use thereof, wherein the voriconazole phosphate salt hydrate prepared by using an isopropanol-water system, ethanol-water system, or an ethanol system comprises different crystal forms. And these kinds of crystal forms have favorable water solubility and stability and feature a simple manufacturing process. The voriconazole phosphate salt hydrate is principally used for treatment of fungal infections.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: May 16, 2017
    Assignee: SHAANXI SYNTHETIC PHARMACEUTICAL Co., LTD.
    Inventor: Qiyuan Zhang
  • VORICONAZOLE SODIUM PHOSPHATE HYDRATES AND POLYMORPHS THEREOF
    Publication number: 20160215008
    Abstract: The present invention relates to a voriconazole sodium phosphate hydrate, polymorphs thereof, a preparation method thereof, and use thereof, wherein the voriconazole phosphate salt hydrate prepared by using an isopropanol-water system, ethanol-water system, or an ethanol system comprises different crystal forms. And these kinds of crystal forms have favorable water solubility and stability and feature a simple manufacturing process. The voriconazole phosphate salt hydrate is principally used for treatment of fungal infections.
    Type: Application
    Filed: September 23, 2014
    Publication date: July 28, 2016
    Applicant: SHAANXI SYNTHETIC PHARMACEUTICAL CO., LTD.
    Inventor: Qiyuan ZHANG