Patents by Inventor Qu Dong

Qu Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
    Publication number: 20090068185
    Abstract: A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
    Type: Application
    Filed: March 9, 2007
    Publication date: March 12, 2009
    Inventors: Kenneth J. Holroyd, Roy C. Levitt, W. Lee Maloy, Jamila Louahed, Mike McLane, Nicholas C. Nicolaides, Yuhong Zhou, Charles Qu Dong
  • Methods for treating ICACC protein associated diseases
    Patent number: 7211254
    Abstract: A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: May 1, 2007
    Assignee: Genaera Corporation
    Inventors: Kenneth J. Holroyd, Roy C. Levitt, W. Lee Maloy, Jamila Louahed, Mike McLane, Nicholas C. Nicolaides, Yuhong Zhou, Qu Dong
  • Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
    Publication number: 20040204578
    Abstract: A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
    Type: Application
    Filed: February 6, 2004
    Publication date: October 14, 2004
    Applicant: Magainin Pharmaceuticals Inc.
    Inventors: Kenneth J. Holroyd, Roy C. Levitt, W. Lee Maloy, Jamila Louahed, Mike McLane, Nicholas C. Nicolaides, Yuhong Zhou, Qu Dong
  • Nucleic acids encoding a chloride channel protein
    Patent number: 6716603
    Abstract: A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: April 6, 2004
    Assignee: Genaera Corporation
    Inventors: Kenneth J. Holroyd, Roy C. Levitt, W. Lee Maloy, Jamila Louahed, Mike McLane, Nicholas C. Nicolaides, Yuhong Zhou, Qu Dong
  • Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
    Publication number: 20030166150
    Abstract: A new gene in the G-coupled protein receptor family is discribed that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and certain lymphomas or leukemias. A method for recombinantly producing the polypeptide encoded by the gene is disclosed. A method for identification and use of agonist and antagonists of GCR9 to treat atopic allergy, asthma-related disorders and certain lymphomas or leukemias is also included. A method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders and certain lymphomas or leukemias by measuring the level of GCR9 in biological samples using antibody specific for the GCR9 polypeptide or nucleic acid probes specific for GCR9 nucleic acids is also disclosed.
    Type: Application
    Filed: January 22, 2003
    Publication date: September 4, 2003
    Applicant: Ludwig Institute for Cancer Research
    Inventors: Jean-Christophe Renauld, Jamila Louahed, Roy Levitt, Nicholas Nicolaides, Qu Dong
  • Methods for identification of agents which modulate chloride channel activity
    Patent number: 6576434
    Abstract: A new gene in the calcium-activated chloride channel family has been discovered that is induced by L-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered.
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: June 10, 2003
    Assignee: Genaera Corporation
    Inventors: Kenneth J. Holroyd, Roy C. Levitt, W. Lee Maloy, Jamila Louahed, Mike McLane, Nicholas C. Nicolaides, Yuhong Zhou, Qu Dong
  • Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
    Publication number: 20030078409
    Abstract: A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
    Type: Application
    Filed: October 16, 2002
    Publication date: April 24, 2003
    Applicant: Magainin Pharmaceuticals Inc.
    Inventors: Kenneth J. Holroyd, Roy C. Levitt, W. Lee Maloy, Jamila Louahed, Mike McLane, Nicholas C. Nicolaides, Yuhong Zhou, Qu Dong