Patents by Inventor Quandeng NIE

Quandeng NIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methyl- and trifluoromethyl-containing disubstituted sulfonamide selective BCL-2 inhibitor
    Patent number: 12319689
    Abstract: Disclosed is a methyl- and trifluoromethyl-containing disubstituted sulfonamide selective BCL-2 inhibitor; specifically disclosed are a compound of formula I, a stereoisomer or pharmaceutically acceptable salt of same, a preparation method therefor, and a pharmaceutical composition comprising the compound. Also disclosed are uses of the compound and of the pharmaceutical composition comprising the compound in treating anti-apoptotic protein BCL-2-related diseases such as cancer.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: June 3, 2025
    Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Fei Liu, Yanlong Liu, Hongjiang Xu, Xiquan Zhang, Shanchun Wang, Jianqing Zhang, Weiwei Feng, Bin Wang, Jinan Wang, Yubing Wang, Xujing Tang, Quandeng Nie
  • METHYL- AND TRIFLUOROMETHYL-CONTAINING DISUBSTITUTED SULFONAMIDE SELECTIVE BCL-2 INHIBITOR
    Publication number: 20220220110
    Abstract: Disclosed is a methyl- and trifluoromethyl-containing disubstituted sulfonamide selective BCL-2 inhibitor; specifically disclosed are a compound of formula I, a stereoisomer or pharmaceutically acceptable salt of same, a preparation method therefor, and a pharmaceutical composition comprising the compound. Also disclosed are uses of the compound and of the pharmaceutical composition comprising the compound in treating anti-apoptotic protein BCL-2-related diseases such as cancer.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 14, 2022
    Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Fei LIU, Yanlong LIU, Hongjiang XU, Xiquan ZHANG, Shanchun WANG, Jianqing ZHANG, Weiwei FENG, Bin WANG, Jinan WANG, Yubing WANG, Xujing TANG, Quandeng NIE