Patents by Inventor Quanfu Chen

Quanfu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11915474
    Abstract: Techniques and apparatus for analyzing visual content using a visual transformer are described. An example technique includes generating a first set of tokens based on a visual content item. Each token in the first set of tokens is associated with a regional feature from a different region of a plurality of regions of the visual content item. A second set of tokens is generated based on the visual content item. Each token in the second set of tokens is associated with a local feature from one of the plurality of regions of the visual content item. At least one feature map is generated for the visual content item, based on analyzing the first set of tokens and the second set of tokens separately using a hierarchical vision transformer. At least one vision task is performed based on the at least one feature map.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: February 27, 2024
    Assignee: International Business Machines Corporation
    Inventors: Richard Chen, Rameswar Panda, Quanfu Fan
  • Patent number: 11660285
    Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: May 30, 2023
    Assignees: Guangdong Provincial Hospital of TCM, The Second Affiliated Hospital Of Guangzhou University of Chinese Medicine, The Second Clinical College Of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy Of Chinese Medical Sciences
    Inventors: Bo Liu, Xianzhang Huang, Zhimin Yang, Jun Li, Quanfu Chen, Liqiao Han, Hualun Liang, Yiqi Yang, Kai Wang, Xiaowan Wang, Ennian Li, Yi Wang, Runyue Huang, Yunshan Wu, Xiaodong Han, Jinlang Zhong, Bidan Zheng
  • Publication number: 20230064939
    Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.
    Type: Application
    Filed: December 30, 2019
    Publication date: March 2, 2023
    Inventors: Bo Liu, Xianzhang Huang, Zhimin Yang, Jun Li, Quanfu Chen, Liqiao Han, Hualun Liang, Yiqi Yang, Kai Wang, Xiaowan Wang, Ennian Li, Yi Wang, Runyue Huang, Yunshan Wu, Xiaodong Han, Jinlang Zhong, Bidan Zheng