Patents by Inventor Quanyi Li

Quanyi Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of cell culture contaminants among Mollicutes species by a PCR based assay
    Patent number: 7872116
    Abstract: The present invention encompasses nucleic acids, methods, compositions, and kits for sensitive, rapid and specific detection of Mycoplasma, Acholeplasma, Ureaplasma, Phytoplasma and Spiroplasma species in a sample. The invention utilizes specific primers and amplification methods that permit differentiation between species due to specific amplification of target nucleic acids of contaminating Mollicute cells. In one embodiment, the invention utilizes the differing melting temperatures (Tm) of various potential PCR products to identify whether they are specific target amplification products, non-specific, non-target amplification products, specific positive control products, or primer-dimer products.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: January 18, 2011
    Assignee: American Type Culture Collection (ATCC)
    Inventors: Pranvera Ikonomi, Deborah Polayes, Karin Cottrill, Quanyi Li
  • Identification of cell culture contaminants among Mollicutes species by a PCR based assay
    Publication number: 20080187916
    Abstract: The present invention encompasses nucleic acids, methods, compositions, and kits for sensitive, rapid and specific detection of Mycoplasma, Acholeplasma, Ureaplasma, Phytoplasma and Spiroplasma species in a sample. The invention utilizes specific primers and amplification methods that permit differentiation between species due to specific amplification of target nucleic acids of contaminating Mollicute cells. In one embodiment, the invention utilizes the differing melting temperatures (Tm) of various potential PCR products to identify whether they are specific target amplification products, non-specific, non-target amplification products, specific positive control products, or primer-dimer products.
    Type: Application
    Filed: February 6, 2007
    Publication date: August 7, 2008
    Inventors: Pranvera Ikonomi, Deborah Polayes, Karin Cottrill, Quanyi Li
  • Methods and compositions for enhancing the delivery of a nucleic acid to a cell
    Patent number: 6919208
    Abstract: The present invention relates to methods and compositions useful for enhancing the efficiency of delivery of a nucleic acid to a cell. Preferably the cell is a mammalian cell. The method comprises providing to a cell an agent capable of enhancing the cytoskeletal permissiveness of the cell for transfection. The method also comprises providing to the cell a nucleic acid delivery system for the transfection of the cell, whereby the efficiency of delivery of a nucleic acid to the cell is enhanced.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: July 19, 2005
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Robert J. Levy, Peter L. Jones, Quanyi Li
  • Methods and compositions for enhancing the delivery of a nucleic acid to a cell
    Publication number: 20050080030
    Abstract: The present invention relates to methods and compositions useful for enhancing the efficiency of delivery of a nucleic acid to a cell. Preferably the cell is a mammalian cell. The method comprises providing to a cell an agent capable of enhancing the cytoskeletal permissiveness of the cell for transfection. The method also comprises providing to the cell a nucleic acid delivery system for the transfection of the cell, whereby the efficiency of delivery of a nucleic acid to the cell is enhanced.
    Type: Application
    Filed: September 5, 2003
    Publication date: April 14, 2005
    Inventors: Robert Levy, Peter Jones, Quanyi Li
  • Methods and compositions for enhancing the delivery of a nucleic acid to a cell
    Publication number: 20020034821
    Abstract: The present invention relates to methods and compositions useful for enhancing the efficiency of delivery of a nucleic acid to a cell. Preferably the cell is a mammalian cell. The method comprises providing to a cell an agent capable of enhancing the cytoskeletal permissiveness of the cell for transfection. The method also comprises providing to the cell a nucleic acid delivery system for the transfection of the cell, whereby the efficiency of delivery of a nucleic acid to the cell is enhanced.
    Type: Application
    Filed: May 9, 2001
    Publication date: March 21, 2002
    Applicant: The Children's Hospital of Philadelphia
    Inventors: Robert J. Levy, Peter L. Jones, Quanyi Li