Patents by Inventor Quanzheng Li

Quanzheng Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12290398
    Abstract: Methods and apparatuses for performing automated detection of lung slide using a computing device (e.g., an ultrasound system, etc.) are disclosed. In some embodiments, the techniques determine lung sliding using one or more neural networks. In some embodiments, the neural networks are part of a process that determines probabilities of the lung sliding at one or more M-lines. In some embodiments, the techniques display one or more probabilities of lung sliding in a B-mode ultrasound image.
    Type: Grant
    Filed: May 2, 2022
    Date of Patent: May 6, 2025
    Assignees: FUJIFILM SONOSITE, INC., MASS GENERAL BRIGHAM
    Inventors: Thomas Michael Duffy, Davinder S. Dhatt, Paul Tomotaro Danset, Adam Benjamin Pely, Christopher Alexksandr White, Diku Pranav Mandavia, Quanzheng Li, Andrew Liteplo, Kyungsang Kim, Suzannah McKinney, Fabiola Macruz
  • Patent number: 12285284
    Abstract: Systems and methods are provided for a deep learning-based digital breast tomosynthesis (DBT) image reconstruction that mitigates limited angular artifacts and improves in-depth resolution of the resulting images. The systems and methods may reduce the sparse-view artifacts in DBT via deep learning without losing image sharpness and contrast. A deep neural network may be trained in a way to reduce training-time computational cost. An ROI loss method may be used for further improvement on the resolution and contrast of the images.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: April 29, 2025
    Assignee: The General Hospital Corporation
    Inventors: Dufan Wu, Kyungsang Kim, Quanzheng Li
  • Publication number: 20240379239
    Abstract: Techniques are described for computer-implemented techniques for managing various aspects of the cardiac care pathway using machine learning. According to an embodiment, a method can include training an outcomes forecasting model to predict patient outcomes resulting from undergoing a cardiac valve procedure using multi-modal training data for a plurality of different patients, wherein the training comprising separately training different machine learning sub-models of the forecasting model to predict preliminary patient outcome data and mapping the preliminary patient outcome data to the patient outcomes, resulting in a trained version of the outcome forecasting model. The method further includes applying the trained version of the outcomes forecasting model to new multi-modal data for a new patient to predict the patient outcomes for the new patient resulting from undergoing the cardiac value procedure.
    Type: Application
    Filed: May 8, 2023
    Publication date: November 14, 2024
    Inventors: Eigil Samset, Xiang Li, Quanzheng Li, Michael H. Picard, Hui Ren, Carola Alejandra Maraboto Gonzalez, Jerome Charton, Abhijit Patil, Mark James Perkins
  • Publication number: 20240144470
    Abstract: An image correction system and method takes an initial volume reconstructed from a number of projections obtained by the imaging system as the sole input to the image correction system. In a first step, the image correction system reconstructs a number of reconstructed or forward projections from the initial volume. In a second and optionally concurrent step, the image correction system forms a corrected volume by applying an artificial intelligence/deep learning/convolutional neural network model to the initial volume. In a third step, the image correction system employs the forward projections and the corrected volume as inputs to an iterative reconstruction process to achieve an optimized volume as an output from the image correction system. The use of the initial volume as the only input to the image correction system simplifies the computational processes of the image processing system while providing an optimized image having improved detail and image quality.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 2, 2024
    Applicant: The General Hospital Corporation
    Inventors: Dufan Wu, Giang-Chau Ngo, Quanzheng Li
  • Publication number: 20230346337
    Abstract: Methods and apparatuses for performing automated detection of lung slide using a computing device (e.g., an ultrasound system, etc.) are disclosed. In some embodiments, the techniques determine lung sliding using one or more neural networks. In some embodiments, the neural networks are part of a process that determines probabilities of the lung sliding at one or more M-lines. In some embodiments, the techniques display one or more probabilities of lung sliding in a B-mode ultrasound image.
    Type: Application
    Filed: May 2, 2022
    Publication date: November 2, 2023
    Inventors: Thomas Michael DUFFY, Davinder S. DHATT, Paul Tomotaro DANSET, Adam Benjamin PELY, Christopher Alexksandr WHITE, Diku Pranav MANDAVIA, Quanzheng LI, Andrew LITEPLO, Kyungsang KIM, Suzannah MCKINNEY, Dr. Fabiola MACRUZ
  • Publication number: 20230110904
    Abstract: Systems and methods are provided for a deep learning-based digital breast tomosynthesis (DBT) image reconstruction that mitigates limited angular artifacts and improves in-depth resolution of the resulting images. The systems and methods may reduce the sparse-view artifacts in DBT via deep learning without losing image sharpness and contrast. A deep neural network may be trained in a way to reduce training-time computational cost. An ROI loss method may be used for further improvement on the resolution and contrast of the images.
    Type: Application
    Filed: January 29, 2021
    Publication date: April 13, 2023
    Inventors: Dufan Wu, Kyungsang Kim, Quanzheng Li
  • Publication number: 20230061863
    Abstract: Systems and methods are provided for a multi-scale deep learning-based digital breast tomosynthesis (DBT) image reconstruction that mitigates the superposition of breast tissue along with the limited angular artifacts, and improves in-depth resolution of the resulting images. A multi-scale deep neural network may be used where a first network may focus on a first parameter, such as limited angular artifacts reduction, and a second network may focus on a second parameter, such as image detail refinement. The output from the first neural network may be used as the input for the second neural network. The systems and methods may reduce the sparse-view artifacts in DBT via deep learning without losing image sharpness and contrast. A deep neural network may be trained in a way to reduce training-time computational cost. An ROI loss method may be used for further improvement on the resolution and contrast of the images.
    Type: Application
    Filed: February 1, 2021
    Publication date: March 2, 2023
    Inventors: Quanzheng Li, Kyungsang Kim, Dufan Wu
  • Publication number: 20230059132
    Abstract: In accordance with one aspect of the disclosure, an image generation system is provided. The system includes at least one processor and at least one non-transitory, computer- readable memory accessible by the processor and having instructions that, when executed by the processor, cause the processor to receive a first patient image associated with a patient, receive a second patient image associated with the patient, train an untrained model based on the first patient image and the second patient image, provide the first patient image to the model, receive a third patient image from the model, and output the third patient image to at least one of a storage system or a display.
    Type: Application
    Filed: September 28, 2020
    Publication date: February 23, 2023
    Inventors: Quanzheng Li, Kuang Gong
  • Publication number: 20230031328
    Abstract: Systems and techniques for monitoring, predicting and/or alerting for short-term oxygen support needs of patients are presented. A system can include a data collection component that receives multimodal patient data for a patient having a respiratory condition in association with monitoring and treating the respiratory condition in real-time, the multimodal patient data comprising at least physiological data regarding physiological parameters tracked for the patient over a period of time, and current oxygen support data regarding a current oxygen support mechanism of the patient.
    Type: Application
    Filed: December 22, 2021
    Publication date: February 2, 2023
    Inventors: Hariharan Ravishankar, Abhijit Patil, Rohit Pardasani, Dirk Johannes Varelmann, Pankaj Sarin, Marcio Aloisio Bezerra Cavalcanti Rockenbach, Quanzheng Li
  • Patent number: 11354830
    Abstract: The present disclosure a system and method for generating a tomographic image of a subject. In some aspects, the method includes receiving an initial image acquired from a subject using the tomographic imaging system, and performing, using the initial image and a cost function model, a penalty calculation based on a spatially variant hyper-parameter. The method also includes generating an updated image using the penalty calculation, and generating a finalized image by iteratively updating the updated image until a stopping criterion is met.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: June 7, 2022
    Assignee: The General Hospital Corporation
    Inventors: Quanzheng Li, Georges El Fakhri, Kyungsang Kim
  • Publication number: 20190272653
    Abstract: The present disclosure a system and method for generating a tomographic image of a subject. In some aspects, the method includes receiving an initial image acquired from a subject using the tomographic imaging system, and performing, using the initial image and a cost function model, a penalty calculation based on a spatially variant hyper-parameter. The method also includes generating an updated image using the penalty calculation, and generating a finalized image by iteratively updating the updated image until a stopping criterion is met.
    Type: Application
    Filed: July 25, 2017
    Publication date: September 5, 2019
    Inventors: Quanzheng Li, Georges El Fakhri, Kyungsang Kim
  • Publication number: 20190133542
    Abstract: Systems and methods for data-driven respiratory gating in positron emission tomography (PET) are provided. In some aspects, a provided method for generating motion information from PET imaging includes receiving time-of-flight (TOF) data acquired using a PET system, and selecting, using at least one image reconstructed from the TOF data, a region of interest (ROI) having tissues subject to motion. The method also includes generating a TOF sinogram mask by projecting an image mask corresponding to the ROI into a sinogram space, and applying the TOF sinogram mask to a TOF sinogram, produced using the TOF data, to identify data in the TOF sinogram associated with motion. The method further includes generating motion information using the data identified.
    Type: Application
    Filed: April 19, 2017
    Publication date: May 9, 2019
    Inventors: Quanzheng Li, Georges El Fakhri, Mengdie Wang
  • Patent number: 10022097
    Abstract: A medical imaging system for reconstructing quantitative dynamic nuclear medicine images of a subject may include a three dimensional positron emission tomography (3D PET) scanner and a data processing system. The three dimensional positron emission tomography (3D PET) scanner may: perform scans of the subject at each of multiple bed positions, each scan being of only a sub-portion of the subject that is within an axial length covered by the scanner; and generate dynamic list-mode PET data that: represents a total number of photon pairs arriving at each of multiple detector pairs in the 3D PET scanner; and is organized in a list of elements, each element in the list including a detector pair index and an arrival time for each detected photon pair; and acquires PET data using a dynamic PET protocol with at least two scans at each of the multiple bed positions.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: July 17, 2018
    Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Richard M. Leahy, Wentao Zhu, Quanzheng Li, Bing Bai, Peter Stephen Conti
  • Patent number: 9928617
    Abstract: A system and method for determining, from registered positron emission tomography (PET) sinogram data and magnetic resonance (MR) image data, an estimated attenuation sinogram uses a data consistency condition to evaluate a gradient of the PET sinogram data using the MR image data. An image of the subject is reconstructed using the estimate attenuation sinogram.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 27, 2018
    Assignee: The General Hospital Corporation
    Inventors: Quanzheng Li, Georges El Fakhri
  • Patent number: 9870627
    Abstract: Described here are systems and methods for reconstructing images from limited angle positron emission tomography (“PET”) data acquired using a PET system with a partial-ring detector configuration, such as an in-beam PET system. The reconstruction process is specifically designed to account for the limited angular coverage of the partial-ring detector by implementing a reduced angle system matrix in an iterative reconstruction process.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: January 16, 2018
    Assignee: The General Hospital Corporation
    Inventors: Georges El Fakhri, Quanzheng Li
  • Patent number: 9495771
    Abstract: Systems and methods for compensating motion artifacts in positron emission tomography (“PET”) imaging based on medical images acquired with a medical imaging system are provided. In some embodiments, the method includes acquiring PET data from a subject with a PET system during which at least a portion of the subject is undergoing motion, and providing medical images acquired from the subject using a medical imaging system, the medical images including regions depicting motion. The method also includes estimating, from the medical images, motion information associated with the motion of the at least a portion of the subject, and reconstructing a motion-corrected PET image using the PET data using a reconstruction algorithm that incorporates the motion information into a system matrix.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: November 15, 2016
    Assignee: The General Hospital Corporation
    Inventors: Georges El Fakhri, Chuan Huang, Jinsong Ouyang, Quanzheng Li, Yoann Petibon, Joyita Dutta
  • Publication number: 20160300366
    Abstract: Described here are systems and methods for reconstructing images from limited angle positron emission tomography (“PET”) data acquired using a PET system with a partial-ring detector configuration, such as an in-beam PET system. The reconstruction process is specifically designed to account for the limited angular coverage of the partial-ring detector by implementing a reduced angle system matrix in an iterative reconstruction process.
    Type: Application
    Filed: April 11, 2016
    Publication date: October 13, 2016
    Inventors: Georges El Fakhri, Quanzheng Li
  • Publication number: 20150363948
    Abstract: A medical imaging system for reconstructing quantitative dynamic nuclear medicine images of a subject may include a three dimensional positron emission tomography (3D PET) scanner and a data processing system. The three dimensional positron emission tomography (3D PET) scanner may: perform scans of the subject at each of multiple bed positions, each scan being of only a sub-portion of the subject that is within an axial length covered by the scanner; and generate dynamic list-mode PET data that: represents a total number of photon pairs arriving at each of multiple detector pairs in the 3D PET scanner; and is organized in a list of elements, each element in the list including a detector pair index and an arrival time for each detected photon pair; and acquires PET data using a dynamic PET protocol with at least two scans at each of the multiple bed positions.
    Type: Application
    Filed: June 15, 2015
    Publication date: December 17, 2015
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Richard M. Leahy, Wentao Zhu, Quanzheng Li, Bing Bai, Peter Stephen Conti
  • Publication number: 20150262389
    Abstract: A system and method for determining, from registered positron emission tomography (PET) sinogram data and magnetic resonance (MR) image data, an estimated attenuation sinogram uses a data consistency condition to evaluate a gradient of the PET sinogram data using the MR image data. An image of the subject is reconstructed using the estimate attenuation sinogram.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 17, 2015
    Inventors: Quanzheng Li, Georges El Fakhri
  • Publication number: 20140334702
    Abstract: Systems and methods for compensating motion artifacts in positron emission tomography (“PET”) imaging based on medical images acquired with a medical imaging system are provided. In some embodiments, the method includes acquiring PET data from a subject with a PET system during which at least a portion of the subject is undergoing motion, and providing medical images acquired from the subject using a medical imaging system, the medical images including regions depicting motion. The method also includes estimating, from the medical images, motion information associated with the motion of the at least a portion of the subject, and reconstructing a motion-corrected PET image using the PET data using a reconstruction algorithm that incorporates the motion information into a system matrix.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 13, 2014
    Inventors: Georges El Fakhri, Chuan Huang, Jinsong Ouyang, Quanzheng Li, Yoann Petibon