Patents by Inventor Qui-Lim Choo

Qui-Lim Choo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis delta viral polypeptides
    Patent number: 5378814
    Abstract: The entire genome of the hepatitis D virus has been shown to be a circular single-stranded RNA of 1679 bases. Several open reading frames in both the genomic and complementary strands indicate possible protein products. The products encoded in one open reading frame. ORF5, are identified as vital polypeptides p24.sup..delta. and p27.sup..delta., of which the nuclear .delta. antigens in HDV infected liver is comprised. These products, as well as others encoded in ORFs 1, 2, 6, and 7 are produced in recombinant expression systems. The ORF5 products, in particular, are useful for HDV diagnosis and vaccines.
    Type: Grant
    Filed: July 9, 1992
    Date of Patent: January 3, 1995
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Kang-Sheng Wang, Qui-Lim Choo, Amy J. Weiner, Lacy R. Overby
  • Hepatitis C virus protease
    Patent number: 5371017
    Abstract: The protease necessary for polyprotein processing in Hepatitis C virus is identified, cloned, and expressed. Proteases, truncated protease, and altered proteases are disclosed which are useful for cleavage of specific polypeptides, and for assay and design of antiviral agents specific for HCV.
    Type: Grant
    Filed: April 4, 1991
    Date of Patent: December 6, 1994
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Qui-Lim Choo, George Kuo
  • HCV immunoassays employing C domain antigens
    Patent number: 5350671
    Abstract: Immunoassays for the detection of antibodies to HCV are provided which employ "C" domain antigens. Immunoassay kits comprising such antigens are also provided.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: September 27, 1994
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Qui-Lim Choo, George Kuo