Patents by Inventor Quintin PAN

Quintin PAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligooxopiperazines for p53 reactivation
    Patent number: 9695153
    Abstract: The present invention relates to oligooxopiperazines for reactivating p53. The oligooxopiperazines comprise two or three oxopiperazine rings and substantially mimic helix ?B of the C-terminal transactivation domain of Hypoxia-Inducible Factor 1?. Methods of using the oligooxopiperazines are also disclosed. Exemplary oligooxopiperazines include those of Formula I below (wherein A, R1, R2, R3, R4, and B are as defined herein).
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: July 4, 2017
    Assignees: New York University, The Ohio State University Research Foundation, The Regents of the University of Michigan
    Inventors: Paramjit S. Arora, Quintin Pan, Anna Mapp
  • Hydrogen-bond surrogate peptides and peptidomimetics for p53 reactivation
    Patent number: 9605026
    Abstract: The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: March 28, 2017
    Assignees: NEW YORK UNIVERSITY, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION, THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Paramjit S. Arora, Quintin Pan, Anna Mapp
  • CBP AND p300-MEDIATED TRANSCRIPTION MODULATORS AND RELATED METHODS
    Publication number: 20150025045
    Abstract: The present invention relates to gene regulation. In particular, the present invention provides small compounds capable of modulating p300 and/or CBP-mediated transcription and related methods of therapeutic and research use. In addition, the present invention provides methods for treating conditions associated with aberrant p300 and/or CBP-mediated transcription with p300 and/or CBP-mediated transcription modulators (e.g., p300 and/or CBP-mediated transcription inhibitors).
    Type: Application
    Filed: September 14, 2012
    Publication date: January 22, 2015
    Applicants: THE OHIO STATE UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Anna Mapp, Quintin Pan
  • ESX-MEDIATED TRANSCRIPTION MODULATORS AND RELATED METHODS
    Publication number: 20150017156
    Abstract: The present invention relates to gene regulation. In particular, the present invention provides small compounds capable of modulating ESX-mediated transcription and related methods of therapeutic and research use. In addition, the present invention provides methods for treating conditions associated with aberrant EGFR expression with ESX-mediated transcription modulators (e.g., ESX-mediated transcription inhibitors).
    Type: Application
    Filed: September 14, 2012
    Publication date: January 15, 2015
    Applicants: THE OHIO STATE UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Anna Mapp, Quintin Pan
  • HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION
    Publication number: 20140220159
    Abstract: The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed.
    Type: Application
    Filed: January 21, 2014
    Publication date: August 7, 2014
    Inventors: Paramjit S. ARORA, Quintin PAN, Anna MAPP
  • OLIGOOXOPIPERAZINES FOR p53 REACTIVATION
    Publication number: 20140205655
    Abstract: The present invention relates to oligooxopiperazines for reactivating p53. Methods of using the oligooxopiperazines are also disclosed.
    Type: Application
    Filed: January 21, 2014
    Publication date: July 24, 2014
    Inventors: Paramjit S. ARORA, Quintin PAN, Anna MAPP
  • HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION
    Publication number: 20140205681
    Abstract: The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed.
    Type: Application
    Filed: January 21, 2014
    Publication date: July 24, 2014
    Inventors: Paramjit S. ARORA, Quintin PAN, Anna MAPP