Patents by Inventor Qunchao Wei

Qunchao Wei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thienopyridine derivatives containing unsaturated aliphatic olefinic bond, preparation method and use thereof
    Patent number: 11466025
    Abstract: The present invention provides a compound having a structure of formula (I), a preparation method and use thereof, and a pharmaceutical composition containing the compound, wherein R is methyl, ethyl, propyl, vinyl or propenyl. The present invention also provides a crystalline form of the compound, a preparation method and use of the crystalline form, and a pharmaceutical composition comprising the crystalline form. The compounds having the structure of formula (I) of the present invention are present in a solid form, which not only can solve the problem of clopidogrel resistance, but also can solve the problem of severe hemorrhagic side effect and poor safety of some drugs, as well as the problem of poor stability of existing compounds. It can be developed into an ADP receptor antagonist antiplatelet agent with clear therapeutic effect, no resistance and better stability.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: October 11, 2022
    Assignee: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.
    Inventors: Changjiang Huang, Shijun Zhang, Lingjun Li, Lei Liu, Yuquan Li, Jing Yuan, Hui Yan, Songhui Wang, Xuemin Zheng, Qunchao Wei, Xuyuan Liu, Wei Wei, Weiren Xu, Lida Tang, Meixiang Zou
  • THIENOPYRIDINE DERIVATIVES CONTAINING UNSATURATED ALIPHATIC OLEFINIC BOND, PREPARATION METHOD AND USE THEREOF
    Publication number: 20200361952
    Abstract: The present invention provides a compound having a structure of formula (I), a preparation method and use thereof, and a pharmaceutical composition containing the compound, wherein R is methyl, ethyl, propyl, vinyl or propenyl. The present invention also provides a crystalline form of the compound, a preparation method and use of the crystalline form, and a pharmaceutical composition comprising the crystalline form. The compounds having the structure of formula (I) of the present invention are present in a solid form, which not only can solve the problem of clopidogrel resistance, but also can solve the problem of severe hemorrhagic side effect and poor safety of some drugs, as well as the problem of poor stability of existing compounds. It can be developed into an ADP receptor antagonist antiplatelet agent with clear therapeutic effect, no resistance and better stability.
    Type: Application
    Filed: August 22, 2018
    Publication date: November 19, 2020
    Applicant: Tianjin Institute of Pharmaceutical Research Co., Ltd.
    Inventors: Changjiang Huang, Shijun Zhang, Lingjun Li, Lei Liu, Yuquan Li, Jing Yuan, Hui Yan, Songhui Wang, Xuemin Zheng, Qunchao Wei, Xuyuan Liu, Wei Wei, Weiren Xu, Lida Tang, Meixiang Zou