Patents by Inventor Qunzhou Zhang

Qunzhou Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240269348
    Abstract: Provided herein is a method of obtaining astrocytes from gingiva-derived mesenchymal stem cells (GDMSC). Also disclosed herein are systems comprising a biocompatible construct and a plurality of astrocytes obtained from a method disclosed herein and methods of making and using the same.
    Type: Application
    Filed: June 3, 2022
    Publication date: August 15, 2024
    Inventors: Daniel Kacy Cullen, John C. O'Donnell, Erin M. Purvis, Anh Le, Qunzhou Zhang
  • Publication number: 20230086560
    Abstract: The present invention includes a functionalized nerve guidance conduit (NGC), methods of making neurotrophic factor-expressing neural crest stem-like cells (NCSC) and/or Schwann cell precursor-like (SCP) cells, methods of making the functionalized nerve guidance conduit, and methods of treating nerve injury using the functionalized nerve guidance conduit.
    Type: Application
    Filed: September 22, 2022
    Publication date: March 23, 2023
    Inventors: Anh D. Le, Qunzhou Zhang
  • Patent number: 9682105
    Abstract: Disclosed are methods of polarizing macrophages to exhibit M2 phenotype, including introducing an effective amount of gingiva-derived mesenchymal stem cells to an environment comprising a population of macrophages such that the macrophages are in fluid communication with the gingiva-derived mesenchymal stem cells. Also disclosed are methods of promoting cutaneous wound healing including administering to a patient an effective amount of human gingiva-derived mesenchymal stem cells, thereby resulting in at least one of accelerated wound closure, rapid re-epithelialization, improved angiogenesis and improved tissue remodeling relative to untreated controls.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: June 20, 2017
    Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Anh D. Le, Qunzhou Zhang
  • Publication number: 20130295058
    Abstract: Disclosed are methods of polarizing macrophages to exhibit M2 phenotype, including introducing an effective amount of gingiva-derived mesenchymal stem cells to an environment comprising a population of macrophages such that the macrophages are in fluid communication with the gingiva-derived mesenchymal stem cells. Also disclosed are methods of promoting cutaneous wound healing including administering to a patient an effective amount of human gingiva-derived mesenchymal stem cells, thereby resulting in at least one of accelerated wound closure, rapid re-epithelialization, improved angiogenesis and improved tissue remodeling relative to untreated controls.
    Type: Application
    Filed: July 14, 2011
    Publication date: November 7, 2013
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Anh D. Le, Qunzhou Zhang
  • Publication number: 20120128636
    Abstract: The present invention relates to gingiva derived messenchymal stem cells (GMSCs). More specifically, the invention provides compositions and methods of using GMSCs to regulate inflammatory response in the setting of normal versus pathological wound healing and to treat inflammatory and/or autoimmune diseases.
    Type: Application
    Filed: January 20, 2010
    Publication date: May 24, 2012
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Anh D. Le, Qunzhou Zhang, Songtao Shi
  • Publication number: 20080038381
    Abstract: A composition comprising a green tea extract (GTE) or its major component, (?)-epigallocatechin-3-gallate (EGCG). Also disclosed is a method of using the composition for keloid scar therapy.
    Type: Application
    Filed: June 22, 2007
    Publication date: February 14, 2008
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Anh Le, Qunzhou Zhang