Patents by Inventor Quoc Mac

Quoc Mac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY PROFILING
    Publication number: 20220185889
    Abstract: Compositions and methods for pharmacodynamic monitoring of immunotherapy are provided herein. The compositions include an immunotherapeutic agent linked to protease substrates. Upon administration, the compositions target to sites of disease where proteases are upregulated during responsive immunotherapy and subsequently cleave the attached substrates. Cleavage fragments are detected in a sample from the body and detection of the fragments is indicative of an effect of the immunotherapeutic agent.
    Type: Application
    Filed: September 11, 2019
    Publication date: June 16, 2022
    Inventors: James Bowen, Gabriel Kwong, Quoc Mac
  • METHODS AND COMPOSITIONS FOR NONINVASIVE DETECTION OF ORGAN TRANSPLANT REJECTION
    Publication number: 20220186285
    Abstract: An activity-based nanosensor composition for detecting protease activity comprising a cleavable detectable substrate and methods of use are disclosed.
    Type: Application
    Filed: January 13, 2022
    Publication date: June 16, 2022
    Inventors: Gabriel A. Kwong, Andrew B. Adams, Quoc Mac, David V. Mathews
  • COMPOSITIONS AND METHODS FOR LOGIC-GATED PROFILING OF BIOLOGIC ACTIVITY
    Publication number: 20200299749
    Abstract: The disclosure provides methods and compositions to digitally profile biological activity by detecting the activity of at least two biomarkers using protease activity sensors or biocomparators.
    Type: Application
    Filed: April 27, 2020
    Publication date: September 24, 2020
    Inventors: Gabriel Kwong, Anirudh Sivakumar, Quoc Mac, Brandon Holt
  • Methods And Compositions For Noninvasive Detection Of Organ Transplant Rejection
    Publication number: 20190345534
    Abstract: An activity-based nanosensor composition for detecting protease activity comprising a cleavable detectable substrate and methods of use are disclosed.
    Type: Application
    Filed: September 28, 2017
    Publication date: November 14, 2019
    Inventors: Gabriel A. Kwong, Andrew B. Adams, Quoc Mac, David V. Mathews