Abstract: A conveyor system 24, 24E, 24F carries work items, such as flexible, pliable, food products 22, through a scanning system 28 which generates data pertaining to various physical parameters of the food products. Thereafter, the food products are transported through a processing station which may be in the form of a portioning system 30. Next, the portioned food products are transported to a harvesting system 32-32F utilizing an actuator 34-34F to unload the food product portions 36 by vacuuming the portions into at least one nozzle 90, 90E, 90F. Such food products are transported to one or more desired locations through a hose/tube connected to a nozzle or may be launched through the air in a trajectory aimed at the desired placement location.

Abstract: The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.

Abstract: The present invention relates to retroviral vectors, particularly lentiviral vectors, comprising a modified retroviral RNA sequence that is codon-substituted and comprises a reduced number of retroviral open-reading frames, and wherein the retroviral vector is pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, methods of making the same and uses thereof.

Abstract: The present disclosure generally relates to compositions and methods for inducing an immune response against S. aureus antigens in a subject. The invention also relates to nucleic acid vaccines and methods of use thereof to treat or prevent diseases or disorders associated with S. aureus infection.

Abstract: The present invention relates to combination treatments for cystic fibrosis, particularly combinations of modulators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and gene therapy.

Abstract: A pair of eyeglasses may include one or more adjustable lenses that are each configured to align with a respective one of a user's eyes. The adjustable lenses may each include electrically modulated optical material such as one or more liquid crystal cells, each having a phase profile that is adjusted using patterned electrodes. Analog voltages may be provided to the patterned electrodes through variable-resistance conductive paths that are each coupled to a subset of the patterned electrodes. Digital voltage selection circuitry may be used to select which analog voltage to apply to each of the variable-resistance conductive paths from a predetermined set of analog voltages that are generated off of the lens. The digital voltage selection circuitry may include an array of multiplexers, each of which selects a desired voltage based on control signals received from digital control circuitry such a shift register and/or a decoder.

Abstract: An electronic device may include one or more ultrasonic temperature sensors. The ultrasonic temperature sensors may be formed in openings or cavities in a housing of the electronic device. The ultrasonic temperature sensors may include ultrasonic transmitters that transmit signals at different ultrasonic frequencies and ultrasonic receivers that receive the transmitted signals. Phase differences between the received ultrasonic signals may be used to determine the speed of sound of ambient air and therefore calculate the temperature of the ambient air. The ultrasonic transmitters and receivers may include piezoelectric micromachined ultrasound transducers (PMUTs). Each transmitter and receiver may be a dedicated transmitter or receiver, or may transmit and receive ultrasonic signals. Each receiver may include an array of PMUTs that receive ultrasonic signals of different frequencies. The PMUTS may be formed on complementary metal-oxide semiconductors (CMOS).

Abstract: A pair of eyeglasses may include one or more adjustable lenses. An adjustable lens may include electrically modulated optical material such as one or more liquid crystal cells having a phase profile that is adjusted using patterned electrodes. Digital-to-analog converter circuits may provide voltages to the electrodes. To save space on the lens, a smaller number of digital-to-analog converter circuits may provide voltages to a greater number of electrodes by sequentially coupling and decoupling the digital-to-analog converter circuits to different groups of electrodes, advancing from group-to-group with each clock cycle by a number of electrodes that is less than the number of digital-to-analog converter circuits. At least one of the electrodes in each group may be driven at the same voltage for two consecutive clock cycles to avoid erroneous voltages resulting from the parasitic capacitance between adjacent fingers.

Abstract: An adjustable hospital bed for laterally positioning a patient includes a support frame having a top end and a bottom end, a plurality of wheels secured to the bottom end of the support frame, and a body pad having a head end and a foot end and a plurality of back pad mortises around its periphery. The bed also includes a back pad having a top edge, a bottom edge, and a plurality of back pad tenons that extend from the bottom edge and are removably inserted into the plurality of back pad mortises of the body pad to support the back pad on its bottom edge at an angle relative to the body pad. In addition, the bed includes a linear actuator configured to lift the head end of the body pad and a tilt adjustment mechanism configured to laterally tilt the body pad.

Abstract: Lock mounting assemblies are disclosed for storing and mounting a locking apparatus to a transportation device. The mounting assemblies include one or more straps or connectors for securing the mounting assembly to the transportation device. The mounting assemblies having a structure to securely retain the locking apparatus on the transportation device and provide easy access to and release of the locking apparatus from the mounting assembly.

Abstract: An apparatus for cryostorage and manipulation of a plurality of container units includes a cryochamber having a cryo-access port. The cryochamber is electrically cooled at cryogenic temperatures. A unit holder is located inside the cryochamber and is configured to hold a plurality of container units. A user access area is provided for selectively permitting access to a chosen container unit by an authenticated user who has been authenticated by the apparatus. A motive grasper is provided for selectively removing the chosen container unit from the cryochamber through the cryo-access port, and selectively placing the chosen container unit into the user access area.

Abstract: An apparatus for cryostorage and manipulation of a plurality of container units includes a cryochamber having a cryo-access port. The cryochamber is electrically cooled at cryogenic temperatures. A unit holder is located inside the cryochamber and is configured to hold a plurality of container units. A user access area is provided for selectively permitting access to a chosen container unit by an authenticated user who has been authenticated by the apparatus. A motive grasper is provided for selectively removing the chosen container unit from the cryochamber through the cryo-access port, and selectively placing the chosen container unit into the user access area.

Abstract: An electronic device may have back-to-back displays. A user-facing display may have microlenses, tunable lens structures, holograms, lasers, and other structures for displaying images in multiple eye boxes while the electronic device is being worn on the head of a user. In some configurations, a switchable diffuser may be incorporated into the user-facing display. In one mode, the switchable diffuser allows microlenses of the pixels of the user-facing display to provide images to eye boxes in which images from the display are viewable. In another mode, the switchable diffuser diffuses light from the pixels so that the user-facing display may be used while the device is being held in the hand of the user.

Abstract: This invention relates to retroviral gene transfer vectors, particularly lentiviral vectors, pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).

Abstract: A toggle cam bolt is provided including a shank, a cam lever, a recess, and a toggle. The shank includes a first end and a second end. The cam lever is rotatably attached to the first end by a first pivot pin. The cam lever includes a lever handle and a cam lobe that is eccentric relative to the first pivot pin. The recess is located at the second end of the shank. The toggle is attached to the recess so that it is rotatable about a second pivot pin. A method of clamping two or more parts together using a toggle cam bolt is also provided.

Abstract: Image-sensing devices include odd-symmetry gratings that cast interference patterns over a photodetector array. Grating features offer considerable insensitivity to the wavelength of incident light, and to the manufactured distance between the grating and the photodetector array. Photographs and other image information can be extracted from interference patterns captured by the photodetector array. Images can be captured without a lens, and cameras can be made smaller than those that are reliant on lenses and ray-optical focusing.

Abstract: Lock mounting assemblies are disclosed for storing and mounting a locking apparatus to a transportation device. The mounting assemblies include one or more straps or connectors for securing the mounting assembly to the transportation device. The mounting assemblies having a structure to securely retain the locking apparatus on the transportation device and provide easy access to and release of the locking apparatus from the mounting assembly.

Abstract: A pair of eyeglasses may include one or more adjustable lenses that are each configured to align with a respective one of a user's eyes. The adjustable lenses may each include electrically modulated optical material such as one or more liquid crystal cells. The liquid crystal cells may include arrays of electrodes that extend along one, two, three, four, or more than four directions. Control circuitry may apply control signals to the array of electrodes in each liquid crystal cell to produce a desired phase profile. Each lens may be foveated such that portions of the lens within the user's gaze exhibit a different phase profile than portions of the lens outside of the user's gaze. The control circuitry may adjust the location of the optically distinct area so that it remains aligned with the user's gaze.

Abstract: A pair of eyeglasses may include one or more adjustable lenses that are each configured to align with a respective one of a user's eyes. The adjustable lenses may include a foveated liquid crystal adjustable lens stacked with a non-liquid-crystal adjustable lens such as a fluid-filled lens or an Alvarez lens. The foveated adjustable lens may include electrically modulated optical material such as one or more liquid crystal cells. The liquid crystal cells may include arrays of electrodes that extend along one, two, three, four, or more than four directions. Control circuitry may apply control signals to the array of electrodes in each liquid crystal cell to produce a desired phase profile. Each lens may be foveated such that portions of the lens within the user's gaze exhibit a different phase profile than portions of the lens outside of the user's gaze.

Abstract: Image-sensing devices include odd-symmetry gratings that cast interference patterns over a photodetector array. Grating features offer considerable insensitivity to the wavelength of incident light, and to the manufactured distance between the grating and the photodetector array. Photographs and other image information can be extracted from interference patterns captured by the photodetector array. Images can be captured without a lens, and cameras can be made smaller than those that are reliant on lenses and ray-optical focusing.