Patents by Inventor R. Bryan Sutton

R. Bryan Sutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12281145
    Abstract: This invention relates to a truncated dysferlin nucleic acid and protein, vectors (e.g., adeno-associated virus vectors) comprising the nucleic acid and methods of using the same for delivery of dysferlin to a cell or a subject and treating dysferlinopathy.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: April 22, 2025
    Assignees: The University of North Carolina at Chapel Hill, Texas Tech University System
    Inventors: Matthew Louis Hirsch, R. Bryan Sutton
  • Publication number: 20220347315
    Abstract: The invention relates to methods and compositions for increasing introduction (e.g., transduction) efficiency. In particular, the invention relates to methods of increasing introduction (e.g., transduction) efficiency by contacting a host cell with a heterologous agent in the presence of a cell membrane fusion protein or a functional fragment or derivative thereof. The invention further relates to compositions that include a heterologous agent and a cell membrane fusion protein or a functional fragment or derivative thereof.
    Type: Application
    Filed: November 20, 2020
    Publication date: November 3, 2022
    Inventors: Chengwen Li, R. Bryan Sutton
  • Publication number: 20200010521
    Abstract: This invention relates to a truncated dysferlin nucleic acid and protein, vectors (e.g., adeno-associated virus vectors) comprising the nucleic acid and methods of using the same for delivery of dysferlin to a cell or a subject and treating dysferlinopathy.
    Type: Application
    Filed: June 16, 2017
    Publication date: January 9, 2020
    Inventors: Matthew Louis Hirsch, R. Bryan Sutton