Patents by Inventor R. Collier

R. Collier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECEPTOR-MEDIATED UPTAKE OF AN EXTRACELLULAR BCL-XL FUSION PROTEIN INHIBITS APOPTOSIS
    Publication number: 20070243190
    Abstract: Apoptosis-modifying fusion polypeptides, and the corresponding nucleic acid molecules, are disclosed. Pharmaceutical compositions comprising these polypeptides, and the use of these polypeptides to modify apoptosis are also provided.
    Type: Application
    Filed: March 27, 2007
    Publication date: October 18, 2007
    Inventors: Richard Youle, Liu Xiuhuai, R. Collier
  • Receptor for B. anthracis toxin
    Publication number: 20070117159
    Abstract: The present invention relates to mammalian anthrax toxin receptor polypeptides and polynucleotides encoding same as well as related polypeptides and polynucleotides, vectors containing the polynucleotides and polypeptides, host cells containing related polynucleotide molecules, and cells displaying no anthrax toxin receptor on an exterior surface of the cells-minus cell lines and animals. The present invention also relates to methods for identifying molecules that bind the anthrax toxin receptor and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.
    Type: Application
    Filed: July 10, 2006
    Publication date: May 24, 2007
    Inventors: John Young, Kenneth Bradley, R. Collier, Jeremy Mogridge
  • RECEPTOR FOR B. ANTHRACIS TOXIN
    Publication number: 20060110801
    Abstract: The present invention relates to mammalian anthrax toxin receptor polypeptides and polynucleotides encoding same as well as related polypeptides and polynucleotides, vectors containing the polynucleotides and polypeptides, host cells containing related polynucleotide molecules, and cells displaying no anthrax toxin receptor on an exterior surface of the cells-minus cell lines and animals. The present invention also relates to methods for identifying molecules that bind the anthrax toxin receptor and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.
    Type: Application
    Filed: October 3, 2001
    Publication date: May 25, 2006
    Inventors: John Young, Kenneth Bradley, R. Collier, Jeremy Mogridge
  • Receptor for B. anthracis toxin
    Publication number: 20060083746
    Abstract: The present invention relates to mammalian anthrax toxin receptor polypeptides and polynucleotides encoding same as well as related polypeptides and polynucleotides, vectors containing the polynucleotides and polypeptides, host cells containing related polynucleotide molecules, and cells displaying no anthrax toxin receptor on an exterior surface of the cells-minus cell lines and animals. The present invention also relates to methods for identifying molecules that bind the anthrax toxin receptor and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.
    Type: Application
    Filed: January 31, 2005
    Publication date: April 20, 2006
    Inventors: John Young, Kenneth Bradley, R. Collier, Jeremy Mogridge