Abstract: For an effective separation of more than one kind of particle from a mixture, a plurality of separation stages are provided, arranged in series. Mixer elements may be disposed along the flow path to disturb the sedimenting particles, to release entrained lighter particles. Further, the separation channel may widen near the particle recovery port(s), to well suspend lighter particles in the fluid as denser particles are extracted and/or to allow gravitational forces to more effectively influence particle movement. In an example embodiment one stage utilizes Coriolis force in a narrow, radial passage for concentrating and agglomerating particles. The serial separation stages may be communicated with a radially inward extending passage to limit undesirable particle spill-over.

Abstract: For an effective separation of more than one kind of particle from a mixture, a plurality of separation stages are provided, arranged in series. Mixer elements may be disposed along the flow path to disturb the sedimenting particles, to release entrained lighter particles. Further, the separation channel may widen near the particle recovery port(s), to well suspend lighter particles in the fluid as denser particles are extracted and/or to allow gravitational forces to more effectively influence particle movement. In an example embodiment one stage utilizes Coriolis force in a narrow, radial passage for concentrating and agglomerating particles. The serial separation stages may be communicated with a radially inward extending passage to limit undesirable particle spill-over.

Abstract: A tube system comprising a blood inlet line with an arterial patient connection and a blood return line with a venous patient connection, where a rinsing liquid inlet line branches off from the blood inlet line downstream from the arterial patient connection, and a rinsing liquid return line branches off from the blood return line upstream from the venous patient connection is filled while maintaining sterility in that rinsing liquid is pumped from a rinsing liquid container through the rinsing liquid inlet line, the blood inlet line, the blood return line and the rinsing liquid return line, establishing a liquid connection between the rinsing liquid inlet line and return line. The venous patient connection is sealed liquid-tight with a venous safety cap, and the arterial patient connection is sealed liquid-tight with an arterial safety cap. The safety caps are removed from the patient connections for connecting the tube system to the patient.

Abstract: A tube system comprising a blood inlet line with an arterial patient connection and a blood return line with a venous patient connection, where a rinsing liquid inlet line branches off from the blood inlet line downstream from the arterial patient connection, and a rinsing liquid return line branches off from the blood return line upstream from the venous patient connection is filled while maintaining sterility in that rinsing liquid is pumped from a rinsing liquid container through the rinsing liquid inlet line, the blood inlet line, the blood return line and the rinsing liquid return line, establishing a liquid connection between the rinsing liquid inlet line and return line. The venous patient connection is sealed liquid-tight with a venous safety cap, and the arterial patient connection is sealed liquid-tight with an arterial safety cap. The safety caps are removed from the patient connections for connecting the tube system to the patient.