Abstract: A cell culture vessel formed generally about an elongate axis and being provided with a neck and a removable closure member, and at a distal end thereof an end closure portion; said vessel being adapted for tissue culture growth and formed of a sterilizable plastics material, wherein the internal surface of the vessel is wettable for the attachment of cells; said vessel being characterized in that its cross-section in a direction perpendicular to said elongate axis is non-cylindrical whereby it cannot rotate smoothly by rolling on its surface(s).