Abstract: A system and computer-implemented method for approving a dynamic mortgage application. In one aspect, the method may include determining a customer is approved for a mortgage and determining a real estate property is mortgage ready, including calculating an appraisal value for the real estate property based upon the information about the real property retrieved from a computer file or memory location/address (such as by using a machine learning or artificial intelligence algorithm). The method may still further include comparing the calculated amount the customer is approved for a mortgage loan with the calculated appraisal value of the real estate property; and approving the mortgage application of the customer for the real estate property when the calculated amount the customer is approved for the mortgage loan meets, or exceeds, the calculated appraisal value of the real estate property.

Abstract: A new fiber optic connector provides a smaller form factor by including two ferrule assemblies in a housing. The housing accepts a push-pull mechanism that allows for insertion and removal from a carrier as well as an adapter. The push-pull mechanism may also include a flexure member to return the push-pull mechanism. Polarity of the fiber optic connector may also be selected by use of the push-pull mechanism.

Abstract: An adapter with novel alignment features engages alignment features on a plug, providing general alignment of the ferrule holders and ferrules in the plug. After the plug engages the adapter, the ferrule holders engage a second set of alignment features in the adapter to provide fine alignment for the ferrules.

Abstract: An adapter with novel alignment features engages alignment features on a plug, providing general alignment of the ferrule holders and ferrules in the plug. After the plug engages the adapter, the ferrule holders engage a second set of alignment features in the adapter to provide fine alignment for the ferrules.

Abstract: Prostamide-containing biodegradable intraocular implants, prostamide compounds, prostamide-containing pharmaceutical compositions, and methods for making and using such implants and compositions for the immediate and sustained reduction of intraocular pressure and treatment of glaucoma in an eye of a patient are described.

Abstract: A system to provide an automated data driven risk relationship review tool via a back-end application computer server of an enterprise. A resource allocation data store may contain electronic records representing requested resource allocations between the enterprise and a plurality of entities. The server may receive an indication of a selected requested resource allocation and retrieve, from the resource allocation data store, the electronic record associated with the selected requested resource allocation. The server may automatically calculate a first and second review date for the selected requested resource allocation and automatically establish, between at least two parties, a communication link based on the calculation of the first review date for the selected requested resource allocation.

Abstract: A new fiber optic connector provides a smaller form factor by including two ferrule assemblies in a housing. The housing accepts a push-pull mechanism that allows for insertion and removal from a carrier as well as an adapter. The push-pull mechanism may also include a flexure member to return the push-pull mechanism. Polarity of the fiber optic connector may also be selected by use of the push-pull mechanism.

Abstract: A system and computer-implemented method of identifying multiple mortgage ready properties. The method includes receiving, via one or more processors, information from a customer approved for a mortgage about preferences for a real estate property and accessing, at a memory coupled to one or more processors, a memory storage location to retrieve a plurality of mortgage ready real estate properties meeting one or more of the customer preferences information. The method further includes transmitting, via the one or more processors, the plurality of real estate properties meeting one or more of the customer preferences information to the customer.

Abstract: According to some embodiments, a system and method for dispensing a floor coating in a specified ratio of multiple components is disclosed. The system and method may set and maintain a desired ratio of the multiple components by controlling, with a controller, a drive rate of respective pumps configured for propelling the components from a reservoir to a mixer or a dispenser. The controller may be responsive to at least one of a measured actual drive rate, an environmental condition, an actual usage of each component, and an operational parameter of the system, for adjusting a drive rate of the respective pumps to compensate for discrepancies that may affect the ratio of the multiple components.

Abstract: A new fiber optic connector provides a smaller form factor by including two ferrule assemblies in a housing. The housing accepts a push-pull mechanism that allows for insertion and removal from a carrier as well as an adapter. The push-pull mechanism may also include a flexure member to return the push-pull mechanism. Polarity of the fiber optic connector may also be selected by use of the push-pull mechanism.

Abstract: A fiber optic connector assembly is mated with a bracket on a printed circuit board at one end and inserted into a backplane adapter that is adjacent a backplane. In particular a spring push in slidingly attached to the bracket and also to the housing of the fiber optic connector assembly. The housing of the fiber optic connector assembly insertable into the backplane adapter using passive alignment features. A fiber optic ferrule in the fiber optic connector assembly is biased in a forward direction by a spring in the spring push. At the same time the spring allows for movement of the spring push within the housing to allow for movement of the printed circuit board relative to the backplane adapter.

Abstract: A transceiver system may include a transmitter, a receiver, an antenna port that is connectable to the transmitter or to the receiver, a filter send port, and a filter return port. The filter ports may be antenna-side or receiver-side, and connectable across at least one filter between the antenna port and the receiver. A transceiver apparatus may include a housing including the transmitter, the receiver, a transceiver switch, and a filter switch assembly in a chamber of the housing. The ports may be accessible through a wall of the housing. A method for filtering a signal include switching, in response to a first signal, a receiver or a transceiver of a transceiver system from an unfiltered path connected to the antenna port to a filtered path connected to the antenna port. The method may further include switching, in response to a second signal, the receiver to the unfiltered path.

Abstract: The present disclosure provides compositions and methods for the genetic modification of cells, including, but not limited to, resting T-cells and hepatocytes. The compositions and methods can comprise lipid nanoparticles, wherein the lipid nanoparticles comprise at least one multivalent cationic bolaform amphiphilic lipid, at least one structural lipid, at least one phospholipid and at least one PEGylated lipid.

Abstract: A bracket for holding a universal transducer for use with a fishing or other boat, including a transducer assembly, having a transducer shaft, which brackets a transducer at its bottom end, while its upper end is connected either to the side of the boat, or onto the upper portions, such as the gear box, of the associated trolling motor, to provide the means for scoping the underwater typography through usage of a universal transducer, as available in the art. The upper end of the transducer shaft connects to a bracket, applied onto the bracket is a geared motor, such as a reversing motor, that can pivot the transducer in an approximate 360-degree direction.

Abstract: A human shoe sole has foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot of the wearer when the human shoe sole is worn; a second region for supporting the wearer's heel when the shoe sole is worn; and a section bridging the first section and the second section. The shoe sole includes a cuboid pad immediately forward the second section configured to underlie essentially the central interior region of the cuboid bone of the wearer, The cuboid pad includes an obliquely running groove or notch on a superior surface of the cuboid pad arranged to align with the location of the peroneus longus tendon of the wearer.

Abstract: Described herein are systems and methods for generating multi-class machine learning classifiers using a plurality of hyper-trained binary classifiers to perform both characteristic detection and object type classification. A range associated with a characteristic of the data sought to be classified may be divided into a plurality of sub-ranges that can be ordered. A plurality of binary machine learning classifiers can be generated, with each binary classifier associated with one of the sub-ranges. Each binary classifier of the plurality of classifiers may be generated by training the classifier to determine if a given input data set contains a characteristic within or outside of the sub-range associated with the binary classifier. Once the binary classifiers have been trained, they can be used to determine what value within the range of the characteristic an input data sample has, and may be used to determine other properties about the input data.

Abstract: A cleat plate for cleated footwear comprising a rigid forefoot plate, a rigid heel plate, and a flexible bridge element connecting the rigid forefoot plate and the rigid heel plate. The rigid forefoot plate includes a concave depression extending downward from the top of the rigid forefoot plate and configured to lie directly under the first metatarsal head of the wearer, wherein the depression extends as a convex surface below the bottom of the rigid forefoot plate and has plurality of cleats extending therefrom.

Abstract: Techniques for simulation of the evolution of a tumor in a prostate gland of a subject are disclosed. The techniques may be based on implementation of a coupled system of reaction-diffusion equations and a patient-specific geometric model of the prostate gland of the subject. The use of reaction-diffusion equations and a patient-specific geometric model provides a tumor model that predicts the expected progression of prostate cancer in the subject. The tumor model may be used to devise a customized treatment for the subject.

Abstract: In an embodiment, a simulation of the evolution of a tumor in a prostate gland of a subject is based at least on a coupled system of reaction-diffusion equations and a patient-specific geometric model of the prostate gland of the subject. The use of reaction-diffusion equations and a patient-specific geometric model provides a tumor model that predicts the expected progression of prostate cancer in the subject. The tumor model may be used to devise a customized treatment for the subject.

Abstract: A trim to fit insole for insertion into a shoe has a raised metatarsal pad on the insole upper surface, wherein the raised metatarsal pad has a first region rising at a slope inboard from a medial edge of the insole board, and configured to underlie the first metatarsal head of the wearer, a second, raised top surface region configured to underlie the second to fourth metatarsal shafts of the wearer, and a third region sloping downward towards the lateral edge of the insole configured to underlie the fifth metatarsal shaft of the wearer, wherein all three regions cooperate to evert the first metatarsal and to invert the fifth metatarsal of the wearer.