Patents by Inventor R. Jason Herr

R. Jason Herr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for preventing, treating and/or protecting against sensory hair cell death
    Patent number: 9902738
    Abstract: Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: February 27, 2018
    Assignees: University of Washington through its Center for Commercialization, Fred Hutchinson Cancer Research Center
    Inventors: Julian Simon, Graham Johnson, Edwin Rubel, Sarwat Chowdhury, R. Jason Herr, Qin Jiang, Xinchao Chen, Kelly N. Owens, David Raible
  • Inhibitors of IRAK4 activity
    Patent number: 9598440
    Abstract: The present invention relates to compounds which modulate interleukin-1 (IL-1) receptor-associated kinase 4 (IRAK4) and are useful in the prevention or treatment of inflammatory, cell proliferative and immune-related conditions and diseases. Specifically, provided herein are inhibitors of IRAK4 of Formula I and pharmaceutical compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: March 21, 2017
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: W. Michael Seganish, William T. McElroy, Stephanie Brumfield, R. Jason Herr, Larry Yet, Jinhai Yang, James P. Harding, III, Ginny Dai Ho, Deen Tulshian, Wensheng Yu, Michael K.C. Wong, Brian Lavey, Joseph A. Kozlowski
  • COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH
    Publication number: 20160326186
    Abstract: Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 10, 2016
    Inventors: Julian SIMON, Graham Johnson, Edwin Rubel, Sarwat Chowdhury, R. Jason Herr, Qin Jiang, Xinchao Chen, Kelly N. Owens, David Raible
  • Compounds and methods for preventing, treating and/or protecting against sensory hair cell death
    Patent number: 9416141
    Abstract: Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: August 16, 2016
    Assignees: University of Washington through its Center for Commercialization, Fred Hutchinson Cancer Research Center
    Inventors: Julian Simon, Graham Johnson, Edwin Rubel, Sarwat Chowdhury, R. Jason Herr, Qin Jiang, Xinchao Chen, Kelly N Owens, David Raible
  • COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH
    Publication number: 20150232476
    Abstract: Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.
    Type: Application
    Filed: September 27, 2013
    Publication date: August 20, 2015
    Inventors: Julian Simon, Graham Johnson, Edwin Rubel, Sarwat Chowdhury, R. Jason Herr, Qin Jiang, Xinchao Chen, Kelly N Owens, David Raible
  • Process for and intermediates in the preparation of canfosfamide and its salts
    Patent number: 8334266
    Abstract: A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: December 18, 2012
    Assignee: Telik, Inc.
    Inventors: William A. Boulanger, Steven J. Collier, Stephen A. Eastham, Dennis L. Edie, Ronan Y. Guevel, Pedro E. Hernandez Abad, R. Jason Herr, Hans J. Kjaersgaard, Harold Meckler, Robert E. Polomski, Steven R. Schow, Pavel E. Zhichkin
  • PROCESS FOR AND INTERMEDIATES IN THE PREPARATION OF CANFOSFAMIDE AND ITS SALTS
    Publication number: 20120238772
    Abstract: A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 20, 2012
    Inventors: William A. Boulanger, Steven J. Collier, Stephen A. Eastham, Dennis L. Edie, Ronan Y. Guevel, Pedro E. Hernández Abad, R. Jason Herr, Hans J. Kjaersgaard, Harold Meckler, Robert E. Polomski, Steven R. Schow, Pavel E. Zhichkin
  • Process for and intermediates in the preparation of canfosfamide and its salts
    Patent number: 8198247
    Abstract: A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: June 12, 2012
    Assignee: Telik, Inc.
    Inventors: William A. Boulanger, Dennis L. Edie, Ronan Y. Guevel, Pedro E. Hernandez Abad, R. Jason Herr, Harold Meckler, Steven R. Schow, Pavel E. Zhichkin
  • Bis-(N,N'-bis-(2-haloethyl)amino)phosphoramidates as antitumor agents
    Patent number: 6506739
    Abstract: Bis-(N,N′-bis-(2-haloethyl)amino)phosphoramidates, pharmaceutical compositions containing them, methods of treatment using them, and processes for their preparation. The compounds possess anti-tumor activities or are capable of being modified to have anti-tumor activities; and this invention relates to the use of the compounds in methods for the treatment of tumors and, especially, for the treatment of cancer.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: January 14, 2003
    Assignee: Telik, Inc.
    Inventors: R. Jason Herr, Robert T. Lum, Steven R. Schow, Fanying Meng, Michael R. Kozlowski, Pavel Zhichkin