Abstract: A multi-lumen coupler for fluid transfer with a plurality of attachable members is provided. The multi-lumen coupler allows the attachment and detachment of various members used for fluid transfer to an elongated percutaneous medical article such as a catheter or cannula, during use with a patient.

Abstract: A waveguide assembly integrated with a semiconductor wafer is provided. The waveguide assembly includes a waveguide channel defined by internal walls of the wafer lined with a metallic layer, and having at least one port for transmission of the RF signal into or out of the waveguide channel. The waveguide assembly also includes a semiconductor obstacle member disposed in the waveguide channel. The waveguide assembly may be fabricated using etching and deposition processes for semiconductor devices. In use, selectively varying either one or both of frequency or power level of electromagnetic radiation applied to the obstacle member varies electrical conductance of the obstacle member, and thereby varies the electrical impedance of the obstacle member to transmission of the RF signal through the waveguide channel. The waveguide assembly may be used for switching, attenuating, routing, filtering, and transforming the RF signal.

Abstract: Systems for efficiently starting an engine of a hybrid electric vehicle are provided. An example of a system comprises a first processor and a second processor. The second processor is configured to determine when to start an internal combustion engine, cause energy to be supplied from an energy storage device to a generator/motor to cause the generator/motor and crankshaft to rotate to at least a hold speed, transmit a first instruction to a first processor when determining that the internal combination engine should be started. The first processor does not supply fuel to at least one cylinder of the internal combustion engine in response to the first instruction. The second processor is configured to transmit a second instruction to the first processor after a variable period of time has elapse after the generator/motor or crankshaft has reached at least the hold speed.

Abstract: Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band.

Abstract: Disclosed herein are thermal heads and corresponding test systems for independently controlling a one or more components while testing one or more devices under test. In some embodiments, a thermal head comprises a plurality of adapters, one or more heaters, and one or more thermal controllers for independently controlling temperatures of the components. The thermal controllers may control the temperatures of at least some of the components independently such that thermal control of one component does not affect the thermal control of the other component. In some embodiments, the thermal control is by way of one or more cold plates, and the thermal head comprises one or more cold plates. Embodiments of the disclosure further include independent control of one or more forces using one or more force mechanisms.

Abstract: The disclosure relates to methods and compositions for regulating expression of DUX4. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy).

Abstract: Yarns are described herein which, in some embodiments, comprise plies or single strands dyed with at least one vat dyestuff yielding a tweed or heathered appearance. In one aspect, a yarn comprises a first ply and a second ply each dyed with at least one vat dyestuff, wherein a difference in color depth (DL*) between the dyed first single strand and the dyed second single strand has an absolute value of at least 2 when the vat dyestuff is in an oxidized state. As described further herein, the first ply and the second ply are dyed in the same dyebath. In another aspect, a yarn comprises a first ply and a second ply each dyed with at least one vat dyestuff, wherein a reflectance ration between the second ply and the first ply ranges from 0.05 to 0.95.

Abstract: Methods and systems are disclosed for apparel assembly using three-dimensional printing directly onto fabric apparel materials. Disclosed is a method and system for direct three-dimensional printing and assembly of an article of apparel, including designing a three-dimensional pattern for printing, positioning at least a portion of the article on a tray in a three-dimensional printing system, the portion being positioned substantially flat on the tray, printing a three-dimensional material directly onto the article using the designed pattern, curing the printed material, and removing the article from the three-dimensional printing system.

Abstract: Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band.

Abstract: An apparatus includes a first jaw (16) and a second jaw (618, 718, 900) that cooperate to clamp and staple tissue (90). The second jaw includes a jaw body (620, 720, 902) and a distal tip (619, 719, 906) pivotable relative to the jaw body between a first discrete and a second discrete position. First and second openings (663, 784, 785, 932, 934) are both defined by one of the distal tip or a structure (621, 920) located proximal to the distal tip. A projection (637, 781, 918) is defined by the other of the distal tip or the structure. The projection is positionable within the first opening (663, 785, 932) to releasably retain the distal tip in the first discrete position, and within the second opening (663, 784, 934) to releasably retain the distal tip in the second discrete position.

Abstract: Systems and methods for manufacturing a composite member. The system and methods are configured to move different types of composite plies from different supply stations. The composite plies are moved along a conveyance member and then with a transfer station to a forming tool. One or more forming members form the composite plies onto the forming tool.

Abstract: Technologies for summarizing tax documents that include an unstructured portion, such as K1 filings. The system extracts data from both the structured information, such as a K1 facepage, and unstructured information, such as whitepaper statement(s). The system includes machine learning model(s) to determine the information to be extracted from the unstructured information. The machine learning model(s) generate a confidence level associated with the extracted unstructured information that represents a prediction on how likely the extracted unstructured information was accurately extracted. The system generates a document in an electronic interchange format that represents both the structured and unstructured information in the analyzed tax document.

Abstract: The present disclosure relates to STING (Stimulator of Interferon Genes) agonist compounds, methods of making the compounds and their methods of use.

Abstract: Systems and methods are provided for assembling a structure. The systems and method including micro pulsing a structure along a track in a process direction by less than a length of the structure. The structure is indexed to one or more work stations by mating indexing features in a manufacturing excess of the structure to complementary features at the work stations. The work stations would the perform work on the structure at the work stations while the structure is indexed to the work stations. Iteratively repeating the micro pulsing and indexing and working upon the structure until it is ready to advance to the next assembly process.

Abstract: Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band.

Abstract: An electric vehicle supply equipment (EVSE) charging station for charging a propulsion battery pack of an electric vehicle (EV) includes a charging cabinet, an electrical cable, and a charge coupler. The charging station is operable for providing a charging voltage or current to the battery pack during a charging operation. The electrical cable has a distal end connected to the charging cabinet. The charge coupler is connected to a proximal end of the electrical cable and connects to a charge receptacle of the EV. The charge coupler includes at least one heating element connected to the charge coupler. The heating element is configured to selectively heat the charge coupler in response to the environmental state being indicative of accumulated snow or ice on the charge coupler.

Abstract: An implantable medical device configured to provide for an intracardiac function comprises a body, a sensor arrangement arranged on the body and configured to receive a cardiac sense signal, and a processing circuitry operatively connected to the sensor arrangement. The processing circuitry is configured to process the cardiac sense signal received using the sensor arrangement to detect, in a cardiac cycle, a first atrial event candidate based on a comparison of the cardiac sense signal with a sense threshold, to determine a modified sense threshold, to monitor, by comparing the cardiac sense signal to said modified sense threshold following the detection of the first atrial event candidate, whether in the same cardiac cycle a second atrial event candidate is detected.

Abstract: An electric vehicle supply equipment (EVSE) charging station for charging a propulsion battery pack of an electric vehicle (EV) includes a charging cabinet, an electrical cable, a charge coupler, and a cradle operable for stowing the charge coupler. The charging station provides a charging voltage or current to the battery pack during a charging operation of the EV. The electrical cable has a distal end connected to the charging cabinet. The charge coupler is connected to a proximal end of the electrical cable and connects to a charge receptacle of the EV. The cradle includes at least one heating element connected thereto. The heating element is configured to selectively heat the cradle body in response to the environmental state of the cradle body being indicative of accumulated snow or ice on the charge coupler and/or the cradle body.

Abstract: An implantable medical device configured to provide for an intracardiac function, the implantable medical device comprises a body, a sensor arrangement arranged on the body and configured to receive cardiac sense signals, and a processing circuitry operatively connected to the sensor arrangement. The processing circuitry is configured to process cardiac sense signals received using the sensor arrangement to detect a signal deflection potentially indicative of an atrial event caused by atrial activity to obtain an atrial detection, to detect a signal deflection indicative of a ventricular event caused by ventricular activity succeeding said atrial detection, to determine an atrial-ventricular interval representing a time between the atrial detection and the ventricular event, and to identify the atrial detection as valid or invalid based on the atrial-ventricular interval.

Abstract: Systems and methods are provided for installing ribs and/or spars to a wing panel while a contour is enforced. Methods include suspending a wing panel beneath a shuttle that enforces the contour, advancing the wing panel through work stations via the shuttle, and installing a rib or a spar (or another wing panel) at a work station, while the contour is enforced. Other methods include locating a wing panel beneath a shuttle, coupling adjustable-length pogos to the wing panel at locations distinct from those corresponding with an installation location, e.g. for a rib or a spar, and controlling the length of the pogos to enforce a contour to the wing panel. Some systems include a track, work stations disposed along the track, and a shuttle to advance along the track and convey a wing panel to each of the work stations while enforcing a contour onto the wing panel.