Abstract: A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The complexes can be covalently attached to an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. In addition certain of the chelant-radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.

Abstract: A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The complexes can be covalently attached to an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. In addition certain of the chelant-radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.

Abstract: This invention relates to novel dicationic and polycationic monoprimary alcohol compounds and their derivatives, represented by the formula ##STR1## wherein each alk is independently alkyl of 1-8 carbon atoms; each ALK is independently alkyl of 1-8 carbon atoms; each R.sub.1, R.sub.2, R.sub.3, R.sub.4 or R.sub.5 is independently H or alkyl of 1-8 carbon atoms; n is 2-5; G is H, CR.sub.1 R.sub.2 CR.sub.3 OHCR.sub.4 R.sub.5 X or ##STR2## X is Cl, Br or I; An.sup.- is an anion and p is 1-10; provided that the compound is soluble in water.

Abstract: The invention is an improvement in a process for making cellulosic articles said process involving a separation of cellulosic material from a mixture containing a liquid, metal cations, and cellulosic material. The improvement involves adding to the mixture at least one retaining material which binds at least one metal cation and, in the separation, is retained with the cellulosic material. Suitable retaining agents are either organic or inorganic and include chelate-forming polymers, both synthetic and natural, colloidal suspensions of inorganic compounds, and mixed metal hydroxides. In each case, the metal cations remain in the cellulosic article, e.g. paper, rather going into waste water from which they would otherwise need to be removed.

Abstract: A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The chelants possess the general formula ##STR1## wherein R.sup.'1, R.sup.'2, R.sup.'3, R.sup.'4, R.sup.'5 and R.sup.'6, Z' and X are all defined in the specification. In addition certain of the chelant-radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.

Abstract: Compositions and method for therapeutic and/or diagnostic treatment of soft tissue tumors in mammals using certain metals ions that are particle-emitting radionuclides, e.g. .sup.153 Sm, complexed with a phenolic carboxylate ligand, e.g. 2,6-bis[N,N-bis(carboxymethyl)aminomethyl]-4-(acetamido)phenol, (bis-IDA), is described.

Abstract: Oral compositions and methods effective in promoting oral hygiene containing in an effective amount at least one cyclic alkylamine or cyclic amine as an antiplaque and/or antigingivitis agent.

Abstract: Oral compositions containing an effective amount as an anticalculus agent at least one cyclic alkylamine or cyclic amine in the presence or absence of a cationic antimicrobial agents.

Abstract: A method for therapeutic and/or diagnostic treatment of soft tumor carcinoma in mammals using certain metals or particle-emitting radionuclides complexed with hydroxyethylethylenediaminetriacetic acid is described.

Abstract: Oral compositions containing phytic acid or a physiologically acceptable salt thereof, a cationic antimicrobial compound and a compatibilizing agent are disclosed for controlling dental calculus, dental plaque, gingivitis, periodontitis and/or oral malodor.