Patents by Inventor R. Kevin Stafford

R. Kevin Stafford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metabolic pathway engineering to increase production of ascorbic acid intermediates
    Patent number: 5032514
    Abstract: In recombinant microorganisms which were rendered capable of converting 2,5-diketo-D-gluconic acid (2,5-DKG) to 2-keto-L-gulonic acid (2-KLG) by transfer of genetic material, the secondary metabolites and metabolic pathways leading to the metabolic diversion of 2-KLG and 2,5-DKG were determined, and the diversion of 2-KLG to L-iodonic acid (IA) or of 2,5-DKG to 5-keto-D-gluconate (5-KDH) was blocked.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: July 16, 1991
    Assignee: Genentech, Inc.
    Inventors: Stephen Anderson, Robert A. Lazarus, Harvey I. Miller, R. Kevin Stafford