Patents by Inventor Rémi Martel

Rémi Martel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabeled DNA carrier, method of preparation and therapeutic uses thereof
    Publication number: 20040067197
    Abstract: The present invention relates to a radiolabeled DNA carrier, a method of preparation thereof and the therapeutic uses of this substance to prevent uncontrolled cellular proliferation. The invention also relates to devices incorporating the above radiolabeled DNA carrier (such as an oligonucleotide) for the therapeutic treatment of uncontrolled cellular proliferation. More specifically, the present invention is concerned with the prevention of restenosis by intravascular delivery of radiolabeled DNA carrier at a dilatation site of an artery. This invention is also directed to a method of treatment of vascular proliferative diseases and/or other proliferative disorders such as cancer and related metastasis.
    Type: Application
    Filed: February 2, 2001
    Publication date: April 8, 2004
    Inventors: Guy Leclerc, Remi Martel
  • Pro-protein converting enzyme
    Patent number: 6380171
    Abstract: The present invention relates to the cloning of human pro-protein converting enzyme 5 (PC5) CDNA isolated from human adrenal gland messenger RNA. Additionally, this invention relates to a method for reducing restenosis occurring at an injured vascular site comprising delivering to the injured site an antisense nucleic acid to suppress the expression of human PC5.
    Type: Grant
    Filed: September 13, 1999
    Date of Patent: April 30, 2002
    Assignees: Clinical Research Institute of Montreal, Universite de Montreal, Centre hospitalier de l'Universite de Montreal
    Inventors: Robert Day, Nabil G. Seidah, Rémi Martel, Michel Chrétien, Tim Reudelhuber, Guy LeClerc
  • Radiolabeled DNA oligonucleotide and method of preparation
    Patent number: 5821354
    Abstract: The present invention relates to a radiolabeled DNA oligonucleotide, a method of preparation thereof and the therapeutic uses of this substance to prevent uncontrolled cellular proliferation. The invention also relates to devices incorporating the above radiolabeled DNA oligonucleotide for the therapeutic treatment of uncontrolled cellular proliferation. More specifically, the present invention is concerned with the prevention of restenosis by coronary delivery of radiolabeled DNA oligonucleotide at a dilatation site of an artery. This invention is also directed to a method of treatment of vascular proliferative diseases and/or other proliferative disorders such as cancer and related metastasis.
    Type: Grant
    Filed: November 26, 1996
    Date of Patent: October 13, 1998
    Assignees: Angiogene Inc., Centre de Recherche du Centre Hospitalier de l'Universite de Montreal
    Inventors: Guy Leclerc, Remi Martel