Abstract: Provided herein are compounds that activate IRE1/XBP1s, and pharmaceutically acceptable derivatives thereof. Also provided are pharmaceutical compositions containing the compounds and methods of using the compounds for treating a subject having a disease or disorder that may be ameliorated by increasing IRE1/XBP1s activity.

Abstract: Methods, systems and devices for controlling mobile device functions via a combination of parental control settings set by a parent-user and parental control settings set by a third party-user. A parental control server receives parental control settings and context criteria from a parent-user, and parental control settings from a third party user. The parental control server receives authorization from the parent-user to allow third party parental controls to control a child's device. When the context criteria identified by the parent is present (e.g., child device is in an identified location, time of day, day of week, etc.), a combination of parental controls designated by the parent-user and the third party control the mobile device.

Abstract: Methods, systems and devices for controlling mobile device functions via a combination of parental control settings set by a parent-user and parental control settings set by a third party-user. A parental control server receives parental control settings and context criteria from a parent-user, and parental control settings from a third party user. The parental control server receives authorization from the parent-user to allow third party parental controls to control a child's device. When the context criteria identified by the parent is present (e.g., child device is in identified location, time of day, day of week, etc.), a combination of parental controls designated by the parent-user and the third party control the mobile device.