Patents by Inventor R. Michael Roberts

R. Michael Roberts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEDIUM SUPPLEMENT TO INCREASE THE EFFICIENCY OF OOCYTE MATURATION AND EMBRYO CULTURE IN VITRO
    Publication number: 20240076611
    Abstract: The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
    Type: Application
    Filed: July 24, 2023
    Publication date: March 7, 2024
    Applicant: The Curators of the University of Missouri
    Inventors: Ye Yuan, Lee D. Spate, Randall S. Prather, R. Michael Roberts
  • Medium supplement to increase the efficiency of oocyte maturation and embryo culture in vitro
    Patent number: 11753622
    Abstract: The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: September 12, 2023
    Assignee: The Curators of the University of Missouri
    Inventors: Ye Yuan, Lee D. Spate, Randall S. Prather, R. Michael Roberts
  • METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION
    Publication number: 20210171912
    Abstract: The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
    Type: Application
    Filed: February 12, 2021
    Publication date: June 10, 2021
    Inventors: Nicholas J. GENOVESE, R. Michael ROBERTS, Bhanu Prakash V. L. TELUGU
  • Method for scalable skeletal muscle lineage specification and cultivation
    Patent number: 10920196
    Abstract: The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: February 16, 2021
    Assignees: The Curators of the University of Missouri, Memphis Meats, Inc.
    Inventors: Nicholas J. Genovese, R. Michael Roberts, Bhanu Prakash V. L. Telugu
  • MEDIUM SUPPLEMENT TO INCREASE THE EFFICIENCY OF OOCYTE MATURATION AND EMBRYO CULTURE IN VITRO
    Publication number: 20210017490
    Abstract: The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
    Type: Application
    Filed: June 3, 2020
    Publication date: January 21, 2021
    Applicant: The Curators of the University of Missouri
    Inventors: Ye Yuan, Lee D. Spate, Randall S. Prather, R. Michael Roberts
  • MEDIUM SUPPLEMENT TO INCREASE THE EFFICIENCY OF OOCYTE MATURATION AND EMBRYO CULTURE IN VITRO
    Publication number: 20170258495
    Abstract: The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
    Type: Application
    Filed: February 28, 2017
    Publication date: September 14, 2017
    Applicant: The Curators of the University of Missouri
    Inventors: Ye Yuan, Lee D. Spate, Randall S. Prather, R. Michael Roberts
  • METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION
    Publication number: 20160251625
    Abstract: The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 1, 2016
    Inventors: Nicholas J. GENOVESE, R. Michael ROBERTS, Bhanu Prakash V.L. TELUGU
  • METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION
    Publication number: 20160227830
    Abstract: The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
    Type: Application
    Filed: April 20, 2016
    Publication date: August 11, 2016
    Inventors: Nicholas J. GENOVESE, R. Michael ROBERTS, Bhanu Prakash V.L. TELUGU
  • Use of interferons of the alpha family to enhance fertility in mammals
    Patent number: 4997646
    Abstract: A method for enhancing the fertility and for prolonging the lifespan of the corpus luteum in female mammals. The method comprising administering to the female mammal an effective amount of an interferon alpha together with one or more pharmaceutically acceptable excipients.
    Type: Grant
    Filed: February 23, 1989
    Date of Patent: March 5, 1991
    Assignees: University of Florida Research Foundation, Inc., Currators of the University of Missouri
    Inventors: Peter J. Hansen, Kazuhiko Imakawa, R. Michael Roberts, William W. Thatcher