Patents by Inventor R. Michael Roe

R. Michael Roe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130005573
    Abstract: Compositions and methods of use for ketones and aldehydes as herbicides are disclosed herein. According to an aspect, a method includes applying an effective amount of an herbicide composition comprising an acyclic, chemically-synthesized or plant-derived ketone or aldehyde of the invention to a locus where undesirable vegetation is to be controlled. The plant-derived or synthesized ketone may be a 2-undecanone. Further, various other acyclic ketones and aldehydes and their derivatives may be used.
    Type: Application
    Filed: March 3, 2011
    Publication date: January 3, 2013
    Applicant: North Carolina State University
    Inventors: R. Michael Roe, George Kennedy
  • Publication number: 20110189251
    Abstract: A method of killing a pest such as an arthropod or invertebrate pest comprises contacting an active agent such as 2-undecanone to said pest in an amount effective to kill said pest. In some embodiments, the contacting step is carried out by applying the active agent such as 2-undecanone or composition containing the same to a plant or animal (e.g., a human, or other mammalian species such as dog, cat, horse, pig, cow sheep, goat, etc.) in an amount substantially non-toxic to said plant or animal. In some embodiments, the contacting step is carried out by applying said active agent such as 2-undecanone as a composition (e.g., an aqueous composition) comprising said 2-undecanone in combination with a soy methyl ester. The composition may be in the form of an emulsion (including microemulsions).
    Type: Application
    Filed: June 24, 2008
    Publication date: August 4, 2011
    Inventors: R. Michael Roe, Allen L. Jones, JR.
  • Patent number: 7455975
    Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.
    Type: Grant
    Filed: January 3, 2007
    Date of Patent: November 25, 2008
    Assignee: ESA Biosciences, Inc.
    Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
  • Patent number: 7288573
    Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 linear or branched alkyl. Particularly preferred compounds of Formula (I) are 2-tridecanone and 2-undecanone.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: October 30, 2007
    Assignee: North Carolina State University
    Inventor: R. Michael Roe
  • Patent number: 7169358
    Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.
    Type: Grant
    Filed: February 25, 2002
    Date of Patent: January 30, 2007
    Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
  • Publication number: 20040242703
    Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: 1
    Type: Application
    Filed: July 23, 2004
    Publication date: December 2, 2004
    Inventor: R. Michael Roe
  • Patent number: 6800662
    Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 linear or branched alkyl. Particularly preferred compounds of Formula (I) are 2-tridecanone and 2-undecanone.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: October 5, 2004
    Assignee: North Carolina State University
    Inventor: R. Michael Roe
  • Publication number: 20040072158
    Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.
    Type: Application
    Filed: February 25, 2002
    Publication date: April 15, 2004
    Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
  • Publication number: 20040034097
    Abstract: The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests Such as mosquitoes, which ingest blood.
    Type: Application
    Filed: August 13, 2003
    Publication date: February 19, 2004
    Inventors: Russell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
  • Patent number: 6660770
    Abstract: The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: December 9, 2003
    Assignee: North Carolina State University
    Inventors: Russell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
  • Publication number: 20030108585
    Abstract: Insecticidal compounds comprising an insecticidal peptide (e.g., juvenile hormone esters) or nucleic acid (e.g. Ea baculovirus) or insecticide covalently conjugated to a polymer are described. Methods of use thereof for controlling insects and compositions containing the same are also described.
    Type: Application
    Filed: October 31, 2002
    Publication date: June 12, 2003
    Inventors: R. Michael Roe, Alan E. Brandt
  • Publication number: 20030083387
    Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: 1
    Type: Application
    Filed: June 21, 2002
    Publication date: May 1, 2003
    Inventor: R. Michael Roe
  • Patent number: 6517856
    Abstract: Methods of assaying insects for pesticide resistance and to identify insect species are based on feeding disruption caused by insecticide such as the biopesticide Bacillius thuringiensis toxin (Bt). Further provided are methods for monitoring insecticide resistance in a population of insects, as well as methods of screening compounds for insecticidal activity. Insecticide resistance can be assessed at the level of an individual insect or at population levels. Apparatus and dehydrated insect meal pads useful in such assays are described.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: February 11, 2003
    Assignees: Agdia Incorporated, North Carolina State University
    Inventors: R. Michael Roe, Woodward D. Bailey, Fred Gould, George G. Kennedy, Chester L. Sutula
  • Publication number: 20020193436
    Abstract: The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.
    Type: Application
    Filed: June 7, 2001
    Publication date: December 19, 2002
    Inventors: Russell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
  • Publication number: 20020187178
    Abstract: Insecticidal compounds comprising an insecticidal peptide (e.g., Juvenile hormone esterase) or nucleic acid (e.g. a baculovirus) covalently conjugated to a water soluble polymer such as polyethylene glycol are described. Methods of use thereof for controlling insects such as moths, and compositions containing the same are also described.
    Type: Application
    Filed: May 3, 2002
    Publication date: December 12, 2002
    Inventor: R. Michael Roe
  • Patent number: 6437001
    Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 linear or branched alkyl. Particularly preferred compounds of Formula (I) are 2-tridecanone and 2-undecanone.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: August 20, 2002
    Assignee: North Carolina State University
    Inventor: R. Michael Roe
  • Patent number: 6391558
    Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: May 21, 2002
    Assignee: Andcare, Inc.
    Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
  • Patent number: 6060039
    Abstract: Methods of assaying insects for pesticide resistance and to identify insect species are based on feeding disruption caused by pesticides such as the biopesticide Bacillus thuringiensis toxin (Bt). The assay end-point is feeding disruption, measured by the fecal production of insects exposed to a diagnostic dose of pesticide in a test diet. Pesticide resistance can be assessed at the level of an individual insect or at population levels. Apparatus useful in such assays are described.
    Type: Grant
    Filed: July 8, 1998
    Date of Patent: May 9, 2000
    Assignee: North Carolina State University
    Inventors: R. Michael Roe, Woodward D. Bailey, Fred Gould, George G. Kennedy