Patents by Inventor R. Roe

R. Roe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130005818
    Abstract: A method for treating glycogen storage disease by administering an effective amount of a composition that includes ketogenic odd carbon fatty acids that ameliorate the symptoms of these diseases.
    Type: Application
    Filed: January 4, 2012
    Publication date: January 3, 2013
    Applicant: BAYLOR RESEARCH INSTITUTE
    Inventor: Charles R. Roe
  • Patent number: 8106093
    Abstract: A method for treating glycogen storage disease by administering an effective amount of a composition that includes ketogenic odd carbon fatty acids that ameliorate the symptoms of these diseases.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: January 31, 2012
    Assignee: Baylor Research Institute
    Inventor: Charles R. Roe
  • Publication number: 20110201558
    Abstract: The present invention describes methods and compositions for the treatment of neurodegenerative conditions including Alzheimer's disease (AD) and aging. The present invention discloses an anaplerotic diet therapy for the treatment of AD. The high fat, low carbohydrate diet described in the various embodiments of the present invention increasing circulating ketone bodies, reduces amyloid-? (A?) deposition in AD patients, thereby improving cognition and locomotive skills.
    Type: Application
    Filed: December 23, 2010
    Publication date: August 18, 2011
    Applicant: Baylor Research Institute
    Inventors: Charles R. Roe, Teodoro G. Bottiglieri
  • Publication number: 20110098677
    Abstract: A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can be used to increase energy production derived from fatty acid metabolism. For example, administering a seven carbon fatty acid chain compound or derivative thereof can be used to accelerate the growth rate of a prematurely born human infant.
    Type: Application
    Filed: June 28, 2010
    Publication date: April 28, 2011
    Applicant: Baylor Research Institute
    Inventor: Charles R. Roe
  • Publication number: 20100222428
    Abstract: A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can be used to increase energy production derived from fatty acid metabolism. For example, administering a seven carbon fatty acid chain compound or derivative thereof can be used to accelerate the growth rate of a prematurely born human infant.
    Type: Application
    Filed: March 8, 2010
    Publication date: September 2, 2010
    Applicant: BAYLOR RESEARCH INSTITUTE
    Inventor: Charles R. Roe
  • Patent number: 7754764
    Abstract: A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can be used to increase energy production derived from fatty acid metabolism. For example, administering a seven carbon fatty acid chain compound or derivative thereof can be used to accelerate the growth rate of a prematurely born human infant.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: July 13, 2010
    Assignee: Baylor Research Institute
    Inventor: Charles R. Roe
  • Patent number: 7705048
    Abstract: A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can be used to increase energy production derived from fatty acid metabolism. For example, administering a seven carbon fatty acid chain compound or derivative thereof can be used to accelerate the growth rate of a prematurely born human infant.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: April 27, 2010
    Inventor: Charles R. Roe
  • Publication number: 20100041755
    Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial ?-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
    Type: Application
    Filed: August 7, 2009
    Publication date: February 18, 2010
    Applicant: BAYLOR RESEARCH INSTITUTE
    Inventor: Charles R. Roe
  • Patent number: 7592370
    Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial ?-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: September 22, 2009
    Assignee: Baylor Research Institute
    Inventor: Charles R. Roe
  • Publication number: 20080132571
    Abstract: The present invention includes compositions and methods for treating the effects of catabolism in a patient by providing the patient with an amount of an odd-chain fatty acid sufficient to increase the intracellular ratio of AMP to ATP and reduce the activity of AMPK.
    Type: Application
    Filed: September 26, 2007
    Publication date: June 5, 2008
    Applicant: BAYLOR RESEARCH INSTITUTE
    Inventor: Charles R. Roe
  • Publication number: 20080050519
    Abstract: The invention comprises a latex formulation. The latex formulation comprises an aqueous emulsion of a natural or synthetic film-forming polymer, hydrogen peroxide, and an activating agent for hydrogen peroxide decomposition. A method of making a latex foam, a method of making a latex-coated textile material, a latex foam and latex foam coated articles are also disclosed.
    Type: Application
    Filed: August 25, 2006
    Publication date: February 28, 2008
    Inventors: Eugene Hubbuch, Claude R. Roe
  • Publication number: 20080050520
    Abstract: The invention comprises a latex formulation. The latex formulation comprises an aqueous emulsion of a natural or synthetic film-forming polymer, hydrogen peroxide, a surfactant and an activating agent for hydrogen peroxide decomposition. A method of making a latex foam, a method of making a latex-coated textile material, a latex foam and latex foam coated articles are also disclosed.
    Type: Application
    Filed: January 29, 2007
    Publication date: February 28, 2008
    Inventors: Eugene T. Hubbuch, Claude R. Roe, Alan P. Sellers
  • Publication number: 20070111202
    Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.
    Type: Application
    Filed: January 3, 2007
    Publication date: May 17, 2007
    Applicant: ANDCARE, INC.
    Inventors: Robert Henkens, John O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Roe, Thomas Stewart, Deborah Thompson, Rebecca Sundseth, Steven Wegner
  • Publication number: 20040152776
    Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial &bgr;-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
    Type: Application
    Filed: December 30, 2003
    Publication date: August 5, 2004
    Inventor: Charles R. Roe
  • Publication number: 20040152773
    Abstract: A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can be used to increase energy production derived from fatty acid metabolism. For example, administering a seven carbon fatty acid chain compound or derivative thereof can be used to accelerate the growth rate of a prematurely born human infant.
    Type: Application
    Filed: December 30, 2003
    Publication date: August 5, 2004
    Inventor: Charles R. Roe
  • Patent number: 6740679
    Abstract: A seven-carbon fatty acid, preferably n-heptanoic acid, has been identified as an excellent energy source for patients suffering from inherited metabolic disorders or acquired metabolic derangements, especially defects in long-chain fatty acid metabolism. A seven-carbon fatty acid can also be provided in a nutritional supplement for patients who need an increase in the energy production derived from fatty acid metabolism.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: May 25, 2004
    Assignee: Baylor University Medical Center
    Inventor: Charles R. Roe
  • Publication number: 20030162833
    Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial &bgr;-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
    Type: Application
    Filed: February 21, 2003
    Publication date: August 28, 2003
    Inventor: Charles R. Roe
  • Publication number: 20030125386
    Abstract: A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can be used to increase energy production derived from fatty acid metabolism. For example, administering a seven carbon fatty acid chain compound or derivative thereof can be used to accelerate the growth rate of a prematurely born human infant.
    Type: Application
    Filed: February 21, 2003
    Publication date: July 3, 2003
    Inventor: Charles R. Roe
  • Patent number: 5629822
    Abstract: A tape cassette shell has mating base and cover sections and azimuth posts that remain perpendicular with respect to the floor or ceiling of the shell sections during cooling after injection molding. At least two support ribs of substantially equal height are formed symmetrically around each azimuth post. Stress imposed on an azimuth post by one support rib due to contraction of the support rib material during cooling after injection molding is balanced by stress imposed on the azimuth post by other support ribs. As a result, the azimuth post remains substantially perpendicular to the floor or ceiling of the shell section during cooling after injection molding. A spring member having leg portions is mounted on support ribs behind the azimuth posts. The leg portions space the spring member up from the top surface of the support ribs.
    Type: Grant
    Filed: November 18, 1994
    Date of Patent: May 13, 1997
    Assignee: Loran Cassettes and Audio Products
    Inventors: Richard F. Rich, James R. Roe
  • Patent number: D378308
    Type: Grant
    Filed: February 20, 1996
    Date of Patent: March 4, 1997
    Inventors: Douglas R. Roe, Harold F. Galbraith