Patents by Inventor R. Ruiz

R. Ruiz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12239732
    Abstract: Methods of administering immunoconjugates that bind to CD37 (e.g., IMGN529) in combination with antibodies that bind to CD20 are provided. The methods comprise administering an anti-CD37 immunoconjugate (e.g., IMGN529) and an anti-CD20 antibody to a person in need thereof, for example, a cancer patient.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: March 4, 2025
    Assignee: DEBIOPHARM INTERNATIONAL, S.A.
    Inventors: Angela Romanelli, Rodrigo R. Ruiz-Soto, Jose Ponte, Jutta Deckert, Jan Pinkas
  • Publication number: 20250031821
    Abstract: The present technology is generally directed to a women's field kit and a field kit system. In various embodiments, the field kit includes a housing having a first body portion releasably coupled to a second body portion, the first body portion and the second body portion collectively defining an interior space, and a plurality of compartments arranged within the interior space. Each compartment of the plurality of compartments may be dimensioned and configured for receiving and storing a respective personal care item. The first body portion may be configured to at least partially separate from the second body portion to allow access to the interior space. The housing may be devoid of any indicia for indicating presence of at least some of the personal care items placed within the kit.
    Type: Application
    Filed: July 26, 2024
    Publication date: January 30, 2025
    Inventors: Ashley R. Ruiz, Tiffany M. Caulfield, Kayla M. Hoke
  • Publication number: 20240299571
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-PD-1 antibodies or antigen-binding fragments thereof (e.g., pembrolizumab) are provided. Methods of administering the combinations to treat cancers, e.g., ovarian, peritoneal, or fallopian tube cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: October 18, 2023
    Publication date: September 12, 2024
    Applicants: ImmunoGen, Inc., Merck Sharp & Dohme LLC
    Inventor: Rodrigo R. RUIZ SOTO
  • Publication number: 20230337868
    Abstract: The present invention provides an apparatus for the delivery of a mist-borne solution substantially contained within a predefined volume. The apparatus thus disclosed is comprised of an active delivery area (herein referred to as a “predefined volume”), at least one detection sensor, a chamber or other suitable area within which to contain an amount of a solution in a liquid state, at least one piezoelectric transducer, and a microcontroller.
    Type: Application
    Filed: March 11, 2021
    Publication date: October 26, 2023
    Applicant: QUANTUM LEAP LLC
    Inventors: Frank R. Ruiz, Henry A. Ruiz, Robert J. Fulbright, Daniel G. Reed, Roberto M. Suárez, William R. Trueba
  • Publication number: 20230190638
    Abstract: Methods of administering immunoconjugates that bind to CD37 (e.g., IMGN529) in combination with antibodies that bind to CD20 are provided. The methods comprise administering an anti-CD37 immunoconjugate (e.g., IMGN529) and an anti-CD20 antibody to a person in need thereof, for example, a cancer patient.
    Type: Application
    Filed: July 25, 2022
    Publication date: June 22, 2023
    Inventors: Angela ROMANELLI, Rodrigo R. RUIZ-SOTO, Jose PONTE, Jutta DECKERT, Jan PINKAS
  • Patent number: 11395796
    Abstract: Methods of administering immunoconjugates that bind to CD37 (e.g., IMGN529) in combination with antibodies that bind to CD20 are provided. The methods comprise administering an anti-CD37 immunoconjugate (e.g., IMGN529) and an anti-CD20 antibody to a person in need thereof, for example, a cancer patient.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: July 26, 2022
    Assignee: Debiopharm International, S.A.
    Inventors: Angela Romanelli, Rodrigo R. Ruiz-Soto, Jose Ponte, Jutta Deckert, Jan Pinkas
  • Publication number: 20220168326
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: February 17, 2022
    Publication date: June 2, 2022
    Inventors: Jose PONTE, Jan PINKAS, Rodrigo R. RUIZ-SOTO
  • Publication number: 20220160889
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-PD-1 antibodies or antigen-binding fragments thereof (e.g., pembrolizumab) are provided. Methods of administering the combinations to treat cancers. e.g., ovarian, peritoneal, or fallopian tube cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: July 21, 2021
    Publication date: May 26, 2022
    Applicants: ImmunoGen, Inc., Merck Sharp & Dohme Corp.
    Inventor: Rodrigo R. RUIZ SOTO
  • Patent number: 11033564
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: June 15, 2021
    Assignee: ImmunoGen, Inc.
    Inventors: Jose Ponte, Jan Pinkas, Rodrigo R. Ruiz-Soto
  • Publication number: 20200397806
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: June 4, 2020
    Publication date: December 24, 2020
    Inventors: Jose PONTE, Jan PINKAS, Rodrigo R. RUIZ-SOTO
  • Publication number: 20190183788
    Abstract: Methods of administering immunoconjugates that bind to CD37 (e.g., IMGN529) in combination with antibodies that bind to CD20 are provided. The methods comprise administering an anti-CD37 immunoconjugate (e.g., IMGN529) and an anti-CD20 antibody to a person in need thereof, for example, a cancer patient.
    Type: Application
    Filed: October 25, 2018
    Publication date: June 20, 2019
    Inventors: Angela Romanelli, Rodrigo R. Ruiz-Soto, Jose Ponte, Jutta Deckert, Jan Pinkas
  • Publication number: 20190167704
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: November 9, 2018
    Publication date: June 6, 2019
    Inventors: Jose PONTE, Jan PINKAS, Rodrigo R. RUIZ-SOTO
  • Patent number: 10172875
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: January 8, 2019
    Assignee: ImmunoGen, inc.
    Inventors: Jose Ponte, Jan Pinkas, Rodrigo R. Ruiz-Soto
  • Publication number: 20180333503
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-PD-1 antibodies or antigen-binding fragments thereof (e.g., pembrolizumab) are provided. Methods of administering the combinations to treat cancers, e.g., ovarian, peritoneal, or fallopian tube cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: May 15, 2018
    Publication date: November 22, 2018
    Applicants: ImmunoGen, Inc., Merck Sharp & Dohme Corp.
    Inventor: Rodrigo R. RUIZ SOTO
  • Publication number: 20170095571
    Abstract: Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.
    Type: Application
    Filed: September 16, 2016
    Publication date: April 6, 2017
    Inventors: Jose PONTE, Jan PINKAS, Rodrigo R. RUIZ-SOTO
  • Publication number: 20170000900
    Abstract: Methods of administering immunoconjugates that bind to CD37 (e.g., IMGN529) in combination with antibodies that bind to CD20 are provided. The methods comprise administering an anti-CD37 immunoconjugate (e.g., IMGN529) and an anti-CD20 antibody to a person in need thereof, for example, a cancer patient.
    Type: Application
    Filed: June 2, 2016
    Publication date: January 5, 2017
    Inventors: Angela ROMANELLI, Rodrigo R. RUIZ-SOTO, Jose PONTE, Jutta DECKERT, Jan PINKAS
  • Publication number: 20150148405
    Abstract: Precursor microRNA molecules that have been modified to prevent a protein involved in regulating developmental timing, oncogenesis, and/or neuronal growth from blocking processing of the precursor microRNA sequence to the mature microRNA are provided. Methods and kits for using the precursor microRNA molecules also are provided.
    Type: Application
    Filed: February 21, 2013
    Publication date: May 28, 2015
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Mollie Katherine Meffert, Claudia R. Ruiz-Garzon, Yu-Wen A. Huang, Elizabeth C. H. Eyler
  • Patent number: 8151260
    Abstract: A method for providing an image of software installed on a computer system is disclosed. The method includes the steps of deconstructing the image into at least one portion and creating at least one module from the at least one portion of the image. The deconstructing step can include the steps of scanning an image and identifying at least one portion of the image to be modularized. The creating step can include the steps of extracting the at least one portion of the image identified to be modularized, generating at least one module from the extracted portion of the image. The modules that are created in accordance with the present invention can be formatted for use in a new image or part of a new image to be used with a software program such as with a hardware-independent imaging tool. Further, the modules can be used with hardware-independent technologies.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: April 3, 2012
    Assignee: Lenovo (Singapore) Pte. Ltd.
    Inventors: Neal R. Caliendo, Jr., Jeffrey M. Estroff, Michaelle L. Fuccella-Walcutt, James A. Hunt, Howard J. Locker, John C. Mese, Joshua N. Nokav, Jose R. Ruiz, Rod D. W. Waltermann, Arnold Weksler
  • Patent number: D655536
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: March 13, 2012
    Inventor: Peter R. Ruiz
  • Patent number: D687277
    Type: Grant
    Filed: April 21, 2012
    Date of Patent: August 6, 2013
    Inventor: Gary R Ruiz