Patents by Inventor R. Sanjeev Saravanan

R. Sanjeev Saravanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC KLEBICINS
    Publication number: 20240010689
    Abstract: The present invention provides chimeric klebicins by combining translocation, receptor-binding, and bactericidal domains originated from different klebicins to achieve improved target cell range and bactericidal activity. Also provided are related compositions, kits, and methods of use of these chimeric klebicins.
    Type: Application
    Filed: July 8, 2022
    Publication date: January 11, 2024
    Inventors: Anisha Ambady, Chemira Biddappa Appaiah, Vivek Daniel Paul, R. Sanjeev Saravanan, Keerthana Anbalagan
  • Therapeutic bacteriocins
    Patent number: 11857606
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: January 2, 2024
    Assignee: BACTOCLEAR HOLDINGS PTE. LTD.
    Inventors: Anisha Ambady, Chemira Biddappa Appaiah, Deepak Balasubramanian, Vivek Daniel Paul, R. Sanjeev Saravanan, Umender Kumar Sharma
  • CHIMERIC PROTEINS FOR SELECTIVE LYSIS OF BACTERIA
    Publication number: 20220378884
    Abstract: The present invention provides chimeric ectolysins useful for selective suppression of certain targeted bacterial species while having little to no effect on closely related non-targeted bacterial species. Specifically, the disclosure provides polypeptides for selective suppression of growth of Staphylococcus aureus and/or S. hominis but not S. epidermidis. Compositions and methods for selective suppression of target bacterial species are also provided.
    Type: Application
    Filed: October 30, 2020
    Publication date: December 1, 2022
    Inventors: Anisha Ambady, Vivek Daniel Paul, R. Sanjeev Saravanan
  • PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
    Publication number: 20220053775
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 24, 2022
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • THERAPEUTIC BACTERIOCINS
    Publication number: 20210163546
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 3, 2021
    Inventors: Anisha Ambady, Chernira Biddappa Appaiah, Deepak Balasubramanian, Vivek Daniel Paul, R. Sanjeev Saravanan, Umender Kumar Sharma
  • PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
    Publication number: 20190297896
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: April 8, 2019
    Publication date: October 3, 2019
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • Phage derived antimicrobial activities
    Patent number: 10278398
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: May 7, 2019
    Assignee: GangaGen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
    Publication number: 20170318817
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: April 7, 2017
    Publication date: November 9, 2017
    Inventors: SRIRAM PADMANABHAN, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • Phage derived antimicrobial activities
    Patent number: 9622486
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: April 18, 2017
    Assignee: Gangagen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • Chimeric antibacterial polypeptides
    Patent number: 9605250
    Abstract: Provided herein are antibacterial compositions and methods of making and using the compositions.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: March 28, 2017
    Assignee: Gangagen, Inc.
    Inventors: Chemira B. Appaiah, Sriram Padmanabhan, R. Sanjeev Saravanan, Bharathi Sriram
  • PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
    Publication number: 20140369986
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: May 15, 2014
    Publication date: December 18, 2014
    Applicant: GangaGen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R.Sanjeev Saravanan, Bharathi Sriram
  • Phage derived antimicrobial activities
    Patent number: 8748150
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: June 10, 2014
    Assignee: GangaGen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • CHIMERIC ANTIBACTERIAL POLYPEPTIDES
    Publication number: 20140050713
    Abstract: Provided herein are antibacterial compositions and methods of making and using the compositions.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 20, 2014
    Inventors: C.B. Appaiah, Sriram Padmanabhan, R. Sanjeev Saravanan, Bharathi Sriram
  • SOLUBLE CYTOPLASMIC EXPRESSION OF HETEROLOGOUS PROTEINS IN ESCHERICHIA COLI
    Publication number: 20130273585
    Abstract: Soluble variants of recombinant proteins produced in a prokaryotic host cell, where the high expression levels often cause the original proteins to aggregate into insoluble inclusion body aggregates. The variant polypeptides retain biological function while increasing protein solubility with comparable or higher recoverable levels of biologically active protein when expressed in a suitable expression host. Methods of identifying critical residues and substituting them are provided to produce the variants.
    Type: Application
    Filed: April 11, 2013
    Publication date: October 17, 2013
    Applicant: GangaGen, Inc.
    Inventors: C. B. Appaiah, Sriram Padmanabhan, R. Sanjeev Saravanan
  • PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
    Publication number: 20120237491
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: May 21, 2012
    Publication date: September 20, 2012
    Applicant: GangaGen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • Phage derived antimicrobial activities
    Patent number: 8202516
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: June 19, 2012
    Assignee: GangaGen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
  • PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
    Publication number: 20090324576
    Abstract: The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
    Type: Application
    Filed: May 4, 2007
    Publication date: December 31, 2009
    Applicant: GangaGen, Inc.
    Inventors: Sriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram