Abstract: Pyrrolidine main protease inhibitors are described that are effective as antiviral compounds.

Abstract: A system to provide an automated data driven risk relationship review tool via a back-end application computer server of an enterprise. A resource allocation data store may contain electronic records representing requested resource allocations between the enterprise and a plurality of entities. The server may receive an indication of a selected requested resource allocation and retrieve, from the resource allocation data store, the electronic record associated with the selected requested resource allocation. The server may automatically calculate a first and second review date for the selected requested resource allocation and automatically establish, between at least two parties, a communication link based on the calculation of the first review date for the selected requested resource allocation.

Abstract: In some implementations a system can be configured to reduce the burden of pairing user devices with playback devices. For example, all users (or user devices) who commonly operate within a particular environment (e.g., a home) can be configured as authorized users of playback devices within the particular environment. When one of the authorized users pairs a user device with a playback device, all of the user devices for all authorized users can be automatically paired with the playback device as a result of the single pairing. Thus, only a single authorized user is burdened with the pairing process in order to pair all authorized users with the playback device.

Abstract: An example medical device includes a device housing configured to be implantable within a patient, the device housing including an internal surface in contact with a voltaic cell of the battery, and a battery external to the device housing and comprising a battery housing configured to be hermetically sealed. The battery is configured to provide electrical power to an electrical component housed within the device housing, and the battery housing is configured to be attached to the device housing. The battery housing includes an internal surface in contact with a voltaic cell of the battery, and an external surface in contact with the biocompatible electrical insulator. an external surface in contact with the biocompatible electrical insulator.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, the medical device having a first lead including a first wire and second wire; a second lead can include a third wire and fourth wire; and a first electrode in electrical communication with the first wire, a second electrode in electrical communication with the second wire, a third electrode in electrical communication with the third wire, and a fourth electrode in electrical communication with the fourth wire. The first and third electrodes form a supply electrode pair configured to deliver one or more electric fields to the cancerous tumor. The second and fourth electrodes form a sensing electrode pair configured to measure an impedance of the cancerous tumor independent of an impedance of the first electrode, the first wire, the third electrode, the third wire, and components in electrical communication therewith. Other embodiments are also included herein.

Abstract: Methods, systems, apparatuses, and computer program products for providing malware protection on a UAV are disclosed. In a particular embodiment, a method of providing malware protection on a UAV includes a malware defense controller initiating, on an unmanned aerial vehicle (UAV) in response to a malware defense event, a malware defense scan of at least one file stored on the UAV. In this embodiment, the malware defense controller also implements, in dependence upon a result of a malware detection analysis, a malware defense operation.

Abstract: Provided herein are methods, compositions and kits to extract and relatively enrich by physical separation or amplification short base pair nucleic acid in the presence of a high background of genomic material (e.g., host or maternal nucleic acids).

Abstract: Cellular base station antenna concealments, such as palm and tree concealments, utilize artificial branches with nonmetallic (e.g., polymeric) interfaces to avoid loose metal-to-metal connections to mitigate the generation of passive intermodulation (PIM) interference by the branches. Representative embodiments include “palm concealments” with low-PIM artificial palm fronds, and “tree concealments” with low-PIM artificial tree branches. That is, “low-PIM fronds” and “low-PIM tree branches” are two representative examples of “low-PIM branches” illustrating representative embodiments of the invention. The low-PIM palm frond includes a nonmetallic (e.g., polymeric) sleeve positioned between a metal frond shaft and a metal frond receiver. A first example of the low-PIM tree branch includes nonmetallic (e.g., polymeric) fastener isolators positioned between metal fasteners and a metal tree branch receiver. A second example of the low-PIM tree branch includes a nonmetallic (e.g.

Abstract: One embodiment provides for a media playback device comprising a memory device to store instructions; one or more processors to execute the instructions stored on the memory device, the instructions to cause the one or more processors to provide a playback queue manager to manage one or more media playback queues including a set of media items associated with a scheduled event and a playback routing manager to determine an output destination for the set of media items based on context associated with the scheduled event, the playback routing manager to route output of playback of the set of media items to one or more of multiple different connected media playback devices based on the context associated with the scheduled event.

Abstract: In a particular embodiment, coordinating an aerial search among unmanned aerial vehicles is disclosed that includes receiving, by a server in a UAV transportation ecosystem, search area data, accessing, by the server, UAV parameters for a type of UAV, determining, by the server in dependence upon the search area data and the UAV parameters, a number of UAVs needed to complete a coordinated aerial search of a search area within a time limit, and partitioning, by the server, the search area into a plurality of partitions, wherein the number of partitions is equal to the number of UAVs.

Abstract: A continuously variable nozzle system includes a nozzle body (5) with an inlet and an outlet. A conduit is defined between the inlet and the outlet by a series connection of components which includes a flow meter (10). The flow meter (10) has a chamber (83) with internal helical splines (82) that are configured to interact with a spray liquid passing through the chamber (83) and create a cyclone-like effect. A sphere (52) is located inside the chamber (83) for free movement along a circular path (106). A sensor is located outside of the chamber (83) and configured to detect motion of the sphere (52) and generate an output (9) signal in response to detected motion.

Abstract: Methods, systems, apparatuses, and computer program products for automated preflight evaluation of an unmanned aerial vehicle (UAV) configuration are disclosed. In a particular embodiment, automated preflight evaluation of an UAV configuration includes a preflight controller retrieving information about a UAV configuration selected to perform a mission in accordance with one or more mission parameters. In this embodiment, the preflight controller uses the retrieved information to assess an ability of the UAV configuration to perform the mission in accordance with the one or more mission parameters.

Abstract: Methods, systems, apparatuses, and computer program products for fulfilling a request associated with operational aspects of an unmanned aerial vehicle (UAV) mission are disclosed. In a particular embodiment, fulfilling a request associated with operational aspects of a UAV mission includes a fulfillment controller presenting to a first set of providers of a plurality of providers, a request for offers to perform a first set of operational aspects of a UAV mission. In this embodiment, the fulfillment controller also includes receiving from each provider of a second set of providers of the plurality of providers, an offer to perform a second set of operational aspects of the first set of operational aspects of the UAV mission. In addition, the fulfillment controller also selects from a first set of offers received from the second set of providers, a first offer to accept.

Abstract: A process of forming a Si-containing ceramic comprises forming a Si-based polymeric composition. The process includes neutralizing a charge of said Si-based polymeric composition. The process includes adding thermal energy under a controlled atmosphere to the Si-based polymeric composition. A turbine engine component comprises an airfoil and the airfoil comprises a Ceramic Matrix Composite (CMC) material.

Abstract: A method of making an electrocaloric article is disclosed. The method includes mounting a supported electrocaloric film to a frame. The supported electrocaloric film includes an electrocaloric film and a first support film disposed on a first side of the electrocaloric film. An active area of the electrocaloric film is provided, which is not covered by the first support film on the first side of the electrocaloric film. Electrical connections are provided to electrodes disposed on opposing sides of the electrocaloric film in the active area.

Abstract: A remote temperature measurement system for a gas turbine engine includes an optical emitter/receiver in communication with the control system and a probe system embedded within a component of the gas turbine engine, the probe system within a line-of-sight of the optical emitter/receiver, the control system operable to determine a local temperature of the component in response to optical communication with the probe system.

Abstract: A fabrication apparatus for fabricating ceramic structures of controlled size and composition is provided. The fabrication apparatus includes an additive manufacturing machine configured to dispense preceramic materials in a printed pattern, the printed pattern corresponding to the ceramic structures of the controlled size and composition, a radiation emitter configured to emit curing radiation toward the printed pattern to cure the preceramic materials and a lamp element configured to shine light on the preceramic materials to convert the preceramic materials to ceramics.

Abstract: A method of forming a bulk product includes the step of coating a particulate conductive phase material with a binder phase, and forming the coated conductive phase material into at least one of sheet stock, tape formed into a bulk material. A method of forming a bulk product includes the step of coating a particulate conductive phase material with a binder phase and forming the coated conductive phase material into a bulk material. The conductive phase material includes at least one of two dimensional materials, single layer materials, carbon nanotubes, boron nitride nanotubes, aluminum nitride and molybdenum disulphide (MoS2). A component is also disclosed.