Patents by Inventor Raakhee Vijayaraghavan

Raakhee Vijayaraghavan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPATIOTEMPORAL EVOLUTION OF TUMOR MICROENVIRONMENTS
    Publication number: 20240384352
    Abstract: Described is a multi-regional, multi-omics approach to uncovering the mechanisms of immune escape in carcinoma. Immunotherapy with ant-PD1 and anti-CTLA4 elicits a heterogeneous immunological response across different regions of the tumor. Several genetic alterations associated with high intra-tumoral heterogeneity (ITH) shape tumor microenvironment (TME).
    Type: Application
    Filed: March 6, 2023
    Publication date: November 21, 2024
    Inventors: Raakhee VIJAYARAGHAVAN, Chen ZHAO, Shile ZHANG, Li LIU, Mahdi GOLKARAM, Michael SALMANS
  • SYSTEM AND METHOD FOR CANCER PROGNOSIS
    Publication number: 20210254170
    Abstract: A potential prognostic biomarker is based on a combination of a composite score generated by sequence analysis of global human endogenous retrovirus (hERV)/retro-transposon transactivation and a cell signature generated using deconvolution of immune cells within a tumor sample for predicting the efficacy of chemotherapeutic agents and immune checkpoint inhibitors. Correlation analysis of the composite score with cell signature within a tumor sample enables survival analysis in individuals receiving chemotherapeutic agents and immune checkpoint inhibitors.
    Type: Application
    Filed: February 10, 2021
    Publication date: August 19, 2021
    Inventors: Mahdi Golkaram, Shile Zhang, Li Liu, Aaron Wise, Joyee Yao, Shannon Kaplan, Alex So, Michael Salmans, Raakhee Vijayaraghavan