Patents by Inventor Rachael Oldinski

Rachael Oldinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Supramolecular alginate materials for biomedical applications
    Patent number: 11331415
    Abstract: The present invention relates to the unexpected discovery of novel hydrogel formulations that allow for the encapsulation and delivery of living cells and/or drugs to a subject in need thereof. In certain embodiments, the hydrogel compositions of the invention comprise bound bioactive molecules that promote long-term cell viability and allows for the development of vasculature. The invention further provides methods of delivering viable cells and/or drugs to a subject comprising administering the compositions of the invention to the subject in need thereof.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: May 17, 2022
    Assignee: UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE
    Inventors: Rachael A. Oldinski, Jennifer N. Etter
  • DECELLULARIZATION AND RECELLULARIZATION OF WHOLE ORGANS
    Publication number: 20210187162
    Abstract: The present invention provides systems and methods for the decellularization and recellularization of tissue segments. In certain instances the invention comprises coating or sealing decellularized tissue segments with a cross-linked alginate hydrogel. The present invention also provides a decellularization kit, which may be used to generate decellularized tissue segments for high throughput studies. Also included are compositions and methods of tissue sealants comprising methacrylated alginate.
    Type: Application
    Filed: January 13, 2021
    Publication date: June 24, 2021
    Inventors: Darcy Wagner, Daniel J. Weiss, Nicholas Bonenfant, Rachael Oldinski, Spencer Fenn
  • Decellularization and recellularization of whole organs
    Patent number: 10918765
    Abstract: The present invention provides systems and methods for the decellularization and recellularization of tissue segments. In certain instances the invention comprises coating or sealing decellularized tissue segments with a cross-linked alginate hydrogel. The present invention also provides a decellularization kit, which may be used to generate decellularized tissue segments for high throughput studies. Also included are compositions and methods of tissue sealants comprising methacrylated alginate.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: February 16, 2021
    Assignee: University of Vermont and State Agricultural College
    Inventors: Darcy Wagner, Daniel J. Weiss, Nicholas Bonenfant, Rachael Oldinski, Spencer Fenn
  • Supramolecular Alginate Materials for Biomedical Applications
    Publication number: 20190314555
    Abstract: The present invention relates to the unexpected discovery of novel hydrogel formulations that allow for the encapsulation and delivery of living cells and/or drugs to a subject in need thereof. In certain embodiments, the hydrogel compositions of the invention comprise bound bioactive molecules that promote long-term cell viability and allows for the development of vasculature. The invention further provides methods of delivering viable cells and/or drugs to a subject comprising administering the compositions of the invention to the subject in need thereof.
    Type: Application
    Filed: April 11, 2019
    Publication date: October 17, 2019
    Inventors: Rachael A. Oldinski, Jennifer N. Etter
  • DECELLULARIZATION AND RECELLULARIZATION OF WHOLE ORGANS
    Publication number: 20160067378
    Abstract: The present invention provides systems and methods for the decellularization and recellularization of tissue segments. In certain instances the invention comprises coating or sealing decellularized tissue segments with a cross-linked alginate hydrogel. The present invention also provides a decellularization kit, which may be used to generate decellularized tissue segments for high throughput studies. Also included are compositions and methods of tissue sealants comprising methacrylated alginate.
    Type: Application
    Filed: April 10, 2014
    Publication date: March 10, 2016
    Inventors: Darcy Wagner, Daniel J. Weiss, Nicholas Bonenfant, Rachael Oldinski, Spencer Fenn