Abstract: Systems and methods for integrating bipedalism augmentation components are provided. A system can receive a request to modify a footwear, comprising a sole formed of an insole and an outsole. The system can select a footplate based on a size of the footwear. The footplate can include a first portion extending along at least a first portion of the sole, a second portion extending along at least a second portion of the sole, wherein the first portion of the footplate has greater rigidity than the second portion, and a mounting component connected to the first portion. The system can provide an indication of the selected the footplate for insertion between the insole and the outsole such that the first portion is located proximate to a heel of the footwear and the mounting component protrudes at least partially from the sole, the mounting component configured to couple to a bracket.

Abstract: Systems and methods for communicating between multiple lower limb exoskeletons are provided. A first exoskeleton boot can receive, responsive to transmitting a first packet, a second packet from a second exoskeleton boot through a wireless connection between the first exoskeleton boot and the second exoskeleton boot. The first exoskeleton boot can determine a latency for communication between the first exoskeleton boot and the second exoskeleton boot based on a time difference between transmission of the first packet and receipt of the second packet and update, responsive to the comparison, a model indicating data weighted based on the latency for controlling the first exoskeleton boot and the second exoskeleton boot. The first exoskeleton boot can generate, using data from the model, a command to cause an electric motor of the first exoskeleton boot to generate torque to aid a limb of a user in performing a movement.

Abstract: Systems and methods for determining a level of collaboration between a user and an exoskeleton boot are provided. A device, using an exoskeleton boot, can provide a level of force to a limb of a user to aid movement of the limb. The device can measure one or more parameters of the exoskeleton boot during the movement of the limb using the exoskeleton boot. The device can determine one or more biometrics of the user during the movement of the limb using the exoskeleton boot. The device can determine, based on the one or more biometrics and the one or more parameters of the device, a metric indicative of a collaboration between the user and the exoskeleton boot during the movement.

Abstract: The invention provides methods to identify moieties which specifically bind the flap-tip helix of the ? subunit of RNA polymerase and to identify inhibitors of the interaction between those moieties and the flap-tip helix.

Abstract: The invention provides methods to identify moieties which specifically bind the flap-tip helix of the ? subunit of RNA polymerase and to identify inhibitors of the interaction between those moieties and the flap-tip helix.

Abstract: The invention provides methods to identify moieties which specifically bind the flap-tip helix of the &bgr; subunit of RNA polymerase and to identify inhibitors of the interaction between those moieties and the flap-tip helix.