Patents by Inventor Rachel Anne McKendry

Rachel Anne McKendry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analyte extraction apparatus and method
    Patent number: 10591496
    Abstract: Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent (2,6 dichloroquinone-4-chloroimide) to the metered portion of the complex sample matrix or the eluent; activating the Gibbs reagent and, after the reaction between the activated Gibbs reagent and the antibiotic has stabilized; detecting the reaction product of the activated Gibbs reagent and the antibiotic in said eluent; and determining the concentration of the antibiotic in the complex sample matrix from the
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: March 17, 2020
    Assignees: Sphere Medical Limited, UCL Business PLC
    Inventors: Natascha Kappeler, Rachel Anne McKendry, Russell Keay, David Pettigrew, Steven Andrew Fowler, Daren Joseph Caruana
  • ANALYTE EXTRACTION APPARATUS AND METHOD
    Publication number: 20180238917
    Abstract: Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent (2,6 dichloroquinone-4-chloroimide) to the metered portion of the complex sample matrix or the eluent; activating the Gibbs reagent and, after the reaction between the activated Gibbs reagent and the antibiotic has stabilized; detecting the reaction product of the activated Gibbs reagent and the antibiotic in said eluent; and determining the concentration of the antibiotic in the complex sample matrix from the
    Type: Application
    Filed: February 20, 2018
    Publication date: August 23, 2018
    Inventors: Natascha Kappeler, Rachel Anne McKendry, Russell Keay, David Pettigrew, Steven Andrew Fowler, Daren Joseph Caruana
  • Analyte extraction apparatus and method
    Patent number: 9897619
    Abstract: Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent (2,6 dichloroquinone-4chloroimide) to the metered portion of the complex sample matrix or the eluent; activating the Gibbs reagent and, after the reaction between the activated Gibbs reagent and the antibiotic has stabilized; detecting the reaction product of the activated Gibbs reagent and the antibiotic in said eluent; and determining the concentration of the antibiotic in the complex sample matrix from the
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: February 20, 2018
    Assignees: Sphere Medical Limited, UCL Business Plc
    Inventors: Natascha Kappeler, Rachel Anne McKendry, Russell Keay, David Pettigrew, Steven Andrew Fowler, Daren Joseph Caruana
  • ANALYTE EXTRACTION APPARATUS AND METHOD
    Publication number: 20160003858
    Abstract: Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent (2,6 dichloroquinone-4chloroimide) to the metered portion of the complex sample matrix or the eluent; activating the Gibbs reagent and, after the reaction between the activated Gibbs reagent and the antibiotic has stabilized; detecting the reaction product of the activated Gibbs reagent and the antibiotic in said eluent; and determining the concentration of the antibiotic in the complex sample matrix from the
    Type: Application
    Filed: February 17, 2014
    Publication date: January 7, 2016
    Inventors: Rachel Anne McKendry, Natascha Kappeler, Russell Keay, David Pettigrew, Steven Andrew Fowler, Daren Joseph Caruana