Patents by Inventor Rachel Auzely

Rachel Auzely has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200062868
    Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a backbone diol function of a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 27, 2020
    Applicants: Galderma Research & Development, Centre National de la Recherche Scientifique
    Inventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
  • Publication number: 20200002441
    Abstract: A new hydrogel made of double crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Double crosslinked glycosaminoglycans, one linkage via two ether bonds with a hydroxyl group of each of two glycosaminoglycans and another linkage via an alkoxyboronate ester anion formed between a boronate hemiester grafted to one of the glycosaminoglycans and a diol function of to the other glycosaminoglycan. The diol function may be a backbone diol function or a diol portion of a diol functional moiety grafted the other glycosaminoglycan.
    Type: Application
    Filed: August 2, 2017
    Publication date: January 2, 2020
    Applicants: Galderma Research & Development, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
  • Publication number: 20190169375
    Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.
    Type: Application
    Filed: August 2, 2017
    Publication date: June 6, 2019
    Applicants: Galderma Research & Development, Centre National de la Recherche Scientifique
    Inventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
  • Patent number: 9549987
    Abstract: Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol modified HA polymer grafted on at least a hydroxyl with a group comprising a cis-diol. Injectable or implantable glucose-sensitive hydrogels comprising a this polymer composition.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: January 24, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER—GRENOBLE 1
    Inventors: Rachel Auzely-Velty, Emilie Hachet, Bogdan Catargi, Valérie Ravaine, Léa Messager
  • Publication number: 20160159937
    Abstract: The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions.
    Type: Application
    Filed: February 12, 2016
    Publication date: June 9, 2016
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Rachel AUZELY, Jimmy MERGY, Eric BAYMA-PECIT
  • Publication number: 20150283247
    Abstract: Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol modified HA polymer grafted on at least a hydroxyl with a group comprising a cis-diol. Injectable or implantable glucose-sensitive hydrogels comprising a this polymer composition.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 8, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Rachel Auzely-Velty, Emilie Hachet, Bogdan Catargi, Valérie Ravaine, Léa Messager
  • Publication number: 20130231474
    Abstract: The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions.
    Type: Application
    Filed: November 18, 2011
    Publication date: September 5, 2013
    Applicant: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Rachel Auzely, Jimmy Mergy, Eric Bayma-Pecit
  • Patent number: 8377418
    Abstract: The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: February 19, 2013
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite Joseph Fourier-Grenoble 1
    Inventors: Rachel Auzely-Velty, Caroline Creuzet
  • Patent number: 8039447
    Abstract: The present invention relates to the use of a compound having the formula (I) wherein: n represents an integer varying from 720 to 6 200, and i varies from 1 to n, Ri represents in particular OH, or a group of the formula (III) wherein k represents an integer varying from 1 to 17, and R?i represents a linear or branched alkyl chain comprising p carbon atoms, wherein p is an integer varying from 1 to 17, with the proviso that k+p is not greater than 28, and preferably not greater than 20, and wherein at least one Ri group represents a group of formula (III), for the preparation of a viscoelastic composition.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: October 18, 2011
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Agro Industrie Recherches et Developpements A.R.D.
    Inventors: Marguerite Rinaudo, Rachel Auzely, Shirin Kadi, Anthony Bresin, Erell Kubik
  • Publication number: 20100204177
    Abstract: The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
    Type: Application
    Filed: September 11, 2008
    Publication date: August 12, 2010
    Inventors: Rachel Auzely-Velty, Caroline Creuzet
  • Publication number: 20080306023
    Abstract: The present invention relates to the use of a compound having the formula (I) wherein: n represents an integer varying from 720 to 6 200, and i varies from 1 to n, Ri represents in particular OH, or a group of the formula (III) wherein k represents an integer varying from 1 to 17, and R?i represents a linear or branched alkyl chain comprising p carbon atoms, wherein p is an integer varying from 1 to 17, with the proviso that k+p is not greater than 28, and preferably not greater than 20, and wherein at least one Ri group represents a group of formula (III), for the preparation of a viscoelastic composition.
    Type: Application
    Filed: November 16, 2006
    Publication date: December 11, 2008
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Agro Industrie Recherches ET Developpments ( A.R.D. )
    Inventors: Marguerite Rinaudo, Rachel Auzely, Shirin Kadi, Anthony Bresin, Erell Kubik
  • Publication number: 20070160557
    Abstract: A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in. cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.
    Type: Application
    Filed: March 15, 2007
    Publication date: July 12, 2007
    Inventors: Claude Dubief, Marguerite Rinaudo, Rachel Auzely-Velty
  • Patent number: 7211268
    Abstract: A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: May 1, 2007
    Assignee: L'Oreal S.A.
    Inventors: Claude Dubief, Marguerite Rinaudo, Rachel Auzely-Velty
  • Patent number: 6858723
    Abstract: The invention provides cyclodextrin derivatives that may be used to transport hydrophobic molecules for pharmaceutical or cosmetic applications, by forming organised systems in an aqueous medium, alone or with phospholipids. The cyclodextrin derivatives of the present invention have the formula: in which, R1 represents a steroid, R2 represents an alkyl or aryl group, substituted if applicable, R3 represents H or R2, all the R4 represent OR2, or one of the R4 represents —NHCO(CH2)mCONHR1, m is an integer ranging from 1 to 8, and n is equal to 5, 6 or 7.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: February 22, 2005
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Rachel Auzely-Velty, Bruno Perly, Florence Djedaini-Pilard
  • Publication number: 20030147818
    Abstract: A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.
    Type: Application
    Filed: November 15, 2002
    Publication date: August 7, 2003
    Inventors: Claude Dubief, Marguerite Rinaudo, Rachel Auzely-Velty