Patents by Inventor Rachel Auzely
Rachel Auzely has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240043574Abstract: A polymer of hyaluronic acid modified by the grafting thereto of at least one of the functions —SO3? and aromatic rings may be used as dopant for a polymer formed from one or monomers chosen from EDOT, ProDOT, and derivatives thereof. An aqueous suspension, or ink, and materials, in particular hydrogels, based on at least one PEDOT and/or PProDOT polymer may be doped by at least one such modified hyaluronic acid polymer. Such modified hyaluronic acid polymers may be used in bioelectronic or biosensor devices.Type: ApplicationFiled: December 16, 2021Publication date: February 8, 2024Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPESInventors: Maxime LEPRINCE, Rachel AUZELY, Isabelle TEXIER-NOGUES
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Patent number: 11807726Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.Type: GrantFiled: November 24, 2021Date of Patent: November 7, 2023Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Rachel Auzely-Velty, Tamiris Figueiredo, Laura Jing Jing, Craig Steven Harris, Jean-Guy Boiteau, Thibaut Gerfaud, Loic Tomas
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Publication number: 20220081519Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.Type: ApplicationFiled: November 24, 2021Publication date: March 17, 2022Applicants: Galderma Research & Development, Centre National de la Recherche ScientifiqueInventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
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Patent number: 11214655Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.Type: GrantFiled: August 2, 2017Date of Patent: January 4, 2022Assignees: GALDERMA RESEARCH & DEVELOPMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTFIQUEInventors: Rachel Auzely-Velty, Tamiris Figueiredo, Laura Jing Jing, Craig Steven Harris, Jean-Guy Boiteau, Thibaut Gerfaud, Loic Tomas
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Publication number: 20200062868Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a backbone diol function of a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.Type: ApplicationFiled: August 2, 2017Publication date: February 27, 2020Applicants: Galderma Research & Development, Centre National de la Recherche ScientifiqueInventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
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Publication number: 20200002441Abstract: A new hydrogel made of double crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Double crosslinked glycosaminoglycans, one linkage via two ether bonds with a hydroxyl group of each of two glycosaminoglycans and another linkage via an alkoxyboronate ester anion formed between a boronate hemiester grafted to one of the glycosaminoglycans and a diol function of to the other glycosaminoglycan. The diol function may be a backbone diol function or a diol portion of a diol functional moiety grafted the other glycosaminoglycan.Type: ApplicationFiled: August 2, 2017Publication date: January 2, 2020Applicants: Galderma Research & Development, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
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Publication number: 20190169375Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.Type: ApplicationFiled: August 2, 2017Publication date: June 6, 2019Applicants: Galderma Research & Development, Centre National de la Recherche ScientifiqueInventors: Rachel AUZELY-VELTY, Tamiris FIGUEIREDO, Laura JING JING, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loic TOMAS
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Patent number: 9549987Abstract: Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol modified HA polymer grafted on at least a hydroxyl with a group comprising a cis-diol. Injectable or implantable glucose-sensitive hydrogels comprising a this polymer composition.Type: GrantFiled: November 6, 2013Date of Patent: January 24, 2017Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER—GRENOBLE 1Inventors: Rachel Auzely-Velty, Emilie Hachet, Bogdan Catargi, Valérie Ravaine, Léa Messager
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Publication number: 20160159937Abstract: The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions.Type: ApplicationFiled: February 12, 2016Publication date: June 9, 2016Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1Inventors: Rachel AUZELY, Jimmy MERGY, Eric BAYMA-PECIT
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Publication number: 20150283247Abstract: Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol modified HA polymer grafted on at least a hydroxyl with a group comprising a cis-diol. Injectable or implantable glucose-sensitive hydrogels comprising a this polymer composition.Type: ApplicationFiled: November 6, 2013Publication date: October 8, 2015Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1Inventors: Rachel Auzely-Velty, Emilie Hachet, Bogdan Catargi, Valérie Ravaine, Léa Messager
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Publication number: 20130231474Abstract: The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions.Type: ApplicationFiled: November 18, 2011Publication date: September 5, 2013Applicant: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1Inventors: Rachel Auzely, Jimmy Mergy, Eric Bayma-Pecit
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Patent number: 8377418Abstract: The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.Type: GrantFiled: September 11, 2008Date of Patent: February 19, 2013Assignees: Centre National de la Recherche Scientifique (CNRS), Universite Joseph Fourier-Grenoble 1Inventors: Rachel Auzely-Velty, Caroline Creuzet
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Patent number: 8039447Abstract: The present invention relates to the use of a compound having the formula (I) wherein: n represents an integer varying from 720 to 6 200, and i varies from 1 to n, Ri represents in particular OH, or a group of the formula (III) wherein k represents an integer varying from 1 to 17, and R?i represents a linear or branched alkyl chain comprising p carbon atoms, wherein p is an integer varying from 1 to 17, with the proviso that k+p is not greater than 28, and preferably not greater than 20, and wherein at least one Ri group represents a group of formula (III), for the preparation of a viscoelastic composition.Type: GrantFiled: November 16, 2006Date of Patent: October 18, 2011Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Agro Industrie Recherches et Developpements A.R.D.Inventors: Marguerite Rinaudo, Rachel Auzely, Shirin Kadi, Anthony Bresin, Erell Kubik
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Publication number: 20100204177Abstract: The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.Type: ApplicationFiled: September 11, 2008Publication date: August 12, 2010Inventors: Rachel Auzely-Velty, Caroline Creuzet
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Publication number: 20080306023Abstract: The present invention relates to the use of a compound having the formula (I) wherein: n represents an integer varying from 720 to 6 200, and i varies from 1 to n, Ri represents in particular OH, or a group of the formula (III) wherein k represents an integer varying from 1 to 17, and R?i represents a linear or branched alkyl chain comprising p carbon atoms, wherein p is an integer varying from 1 to 17, with the proviso that k+p is not greater than 28, and preferably not greater than 20, and wherein at least one Ri group represents a group of formula (III), for the preparation of a viscoelastic composition.Type: ApplicationFiled: November 16, 2006Publication date: December 11, 2008Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Agro Industrie Recherches ET Developpments ( A.R.D. )Inventors: Marguerite Rinaudo, Rachel Auzely, Shirin Kadi, Anthony Bresin, Erell Kubik
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Publication number: 20070160557Abstract: A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in. cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.Type: ApplicationFiled: March 15, 2007Publication date: July 12, 2007Inventors: Claude Dubief, Marguerite Rinaudo, Rachel Auzely-Velty
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Patent number: 7211268Abstract: A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.Type: GrantFiled: November 15, 2002Date of Patent: May 1, 2007Assignee: L'Oreal S.A.Inventors: Claude Dubief, Marguerite Rinaudo, Rachel Auzely-Velty
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Patent number: 6858723Abstract: The invention provides cyclodextrin derivatives that may be used to transport hydrophobic molecules for pharmaceutical or cosmetic applications, by forming organised systems in an aqueous medium, alone or with phospholipids. The cyclodextrin derivatives of the present invention have the formula: in which, R1 represents a steroid, R2 represents an alkyl or aryl group, substituted if applicable, R3 represents H or R2, all the R4 represent OR2, or one of the R4 represents —NHCO(CH2)mCONHR1, m is an integer ranging from 1 to 8, and n is equal to 5, 6 or 7.Type: GrantFiled: April 26, 2000Date of Patent: February 22, 2005Assignee: Commissariat a l'Energie AtomiqueInventors: Rachel Auzely-Velty, Bruno Perly, Florence Djedaini-Pilard
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Publication number: 20030147818Abstract: A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.Type: ApplicationFiled: November 15, 2002Publication date: August 7, 2003Inventors: Claude Dubief, Marguerite Rinaudo, Rachel Auzely-Velty