Abstract: Genetically modified cells with at least one codon substituted to a synonymous codon, and with modified replicative fitness as compared to the unmodified cell, wherein a slower translating synonymous codon increases replicative fitness and a faster translating codon decreased replicative fitness are provided. Further, vaccine composition comprising those cells as well as methods for modifying replicative fitness of a cell are provided.

Abstract: Genetically modified cells with at least one codon substituted to a synonymous codon, and with modified replicative fitness as compared to the unmodified cell, wherein a slower translating synonymous codon increases replicative fitness and a faster translating codon decreased replicative fitness are provided. Further, vaccine composition comprising those cells as well as methods for modifying replicative fitness of a cell are provided.

Abstract: A method and system for improving document lifecycle editing and storage technology is provided. The method includes enabling interactions between a user and a hardware controller. Editor profiles associated with editing privileges of the user are generated. The editor profiles include parameters generated based on a performance of past edits. The editing tasks are automated task difficulty attributes associated with a difficulty of executing the editing tasks are generated. The editing tasks may include readability and consolidation tasks. An optimized version of the editing tasks is assigned to software editors and time periods associated with the software editors completing the editing tasks are tracked. The optimized version of the editing tasks is generated based on the editor profiles and new tasks for assignment. User permissions and alerts are monitored and recommendation actions associated with the editing tasks are generated. The editing tasks are modified for future execution.

Abstract: A method and system for improving linguistic data and storage technology is provided. The method includes receiving data input text from a user and identifying text within the data input text. The data input text is edited and improvements in the data input text are detected via a machine learning process. In response, a modified version of the user interface is generated for allowing additional users to view and modify additional data input text. Change attributes associated with the data input text with respect to the modified version of the user interface are determined and alternative input suggestions are ranked. Editing data and code are generated in response to an editor engine interacting with a hardware controller. The editing data and code is executed thereby updating and modifying functions associated with software engines to increase an efficiency of future recommendations associated with future data input text analysis.

Abstract: A method and system for improving document lifecycle editing and storage technology is provided. The method includes enabling interactions between a user and a hardware controller. Editor profiles associated with editing privileges of the user are generated. The editor profiles include parameters generated based on a performance of past edits. The editing tasks are automated task difficulty attributes associated with a difficulty of executing the editing tasks are generated. The editing tasks may include readability and consolidation tasks. An optimized version of the editing tasks is assigned to software editors and time periods associated with the software editors completing the editing tasks are tracked. The optimized version of the editing tasks is generated based on the editor profiles and new tasks for assignment. User permissions and alerts are monitored and recommendation actions associated with the editing tasks are generated. The editing tasks are modified for future execution.

Abstract: A method and system for improving linguistic data and storage technology is provided. The method includes receiving data input text from a user and identifying text within the data input text. The data input text is edited and improvements in the data input text are detected via a machine learning process. In response, a modified version of the user interface is generated for allowing additional users to view and modify additional data input text. Change attributes associated with the data input text with respect to the modified version of the user interface are determined and alternative input suggestions are ranked. Editing data and code are generated in response to an editor engine interacting with a hardware controller. The editing data and code is executed thereby updating and modifying functions associated with software engines to increase an efficiency of future recommendations associated with future data input text analysis.

Abstract: Technologies for managing power consumption include a power management device that determines a context associated with a user of computing devices located within a building and in communication with the power management device. The power management device compares the context associated with the user to a power management policy. The power management policy includes power management rules that define power consumption levels for the computing devices based on the context associated with the user. The power management device communicates with the computing devices to adjust the power consumption levels in response to the context associated with the user satisfying a power management rule.

Abstract: Genetically modified cells with at least one codon substituted to a synonymous codon, and with modified replicative fitness as compared to the unmodified cell, wherein a slower translating synonymous codon increases replicative fitness and a faster translating codon decreased replicative fitness are provided. Further, vaccine composition comprising those cells as well as methods for modifying replicative fitness of a cell are provided.

Abstract: Technologies for managing power consumption include a power management device that determines a context associated with a user of computing devices located within a building and in communication with the power management device. The power management device compares the context associated with the user to a power management policy. The power management policy includes power management rules that define power consumption levels for the computing devices based on the context associated with the user. The power management device communicates with the computing devices to adjust the power consumption levels in response to the context associated with the user satisfying a power management rule.

Abstract: The subject invention provides R(+)-N-formyl-propargyl-aminoindan and a composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of R(+)-N-formyl-propargyl-aminoindan.

Abstract: The subject invention provides R(+)-N-methyl-propargyl-aminoindan or a pharmaceutically acceptable salt thereof and a composition containing R(+)-N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of R(+)-N-methyl-propargyl-aminoindan or a salt thereof.

Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.

Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.

Abstract: Anti-A?P scFvs and single domain antibodies were generated, and when these antibodies were displayed on filamentous phage or as soluble protein molecules, stabilized by the maltose binding protein, they could prevent the fibrilization of A?p 1-40 and disaggregate A?p 1-40 fibrils generated in vitro. The anti-A?p scFv antibodies also stained amyloid neuritic plaques on slices from transgenic mice. The anti-A?P scFv and single domain antibodies can be used for inhibiting or treating Alzheimer's disease.

Abstract: Anti-A?P scFvs and single domain antibodies were generated, and when these antibodies were displayed on filamentous phage or as soluble protein molecules, stabilized by the maltose binding protein, they could prevent the fibrilization of A?p 1-40 and disaggregate A?p 1-40 fibrils generated in vitro. The anti-A?p scFv antibodies also stained amyloid neuritic plaques on slices from transgenic mice. The anti-A?P scFv and single domain antibodies can be used for inhibiting or treating Alzheimer's disease.

Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.

Abstract: Anti-A?P scFvs and single domain antibodies were generated, and when these antibodies were displayed on filamentous phage or as soluble protein molecules, stabilized by the maltose binding protein, they could prevent the fibrilization of Abp 1-40 and disaggregate Abp 1-40 fibrils generated in vitro. The anti-A?p scFv antibodies also stained amyloid neuritic plaques on slices from transgenic mice. The anti-A?P scFv and single domain antibodies can be used for inhibiting or treating Alzheimer's disease.

Abstract: Disclosed are formulations of rasagiline base which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. Also, disclosed are rasagiline citrate salt and the use and process of manufacture thereof.

Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.

Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.