Patents by Inventor Rachel Dutton

Rachel Dutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIMICROBIAL AGENTS AND SCREENING METHODS
    Publication number: 20170173008
    Abstract: Disclosed herein are antibacterial and antimicrobial compositions and methods of use. Also disclosed are screening assays for identification of an agent that specifically inhibits DsbB or bVKOR. Such methods are useful, for example, in identifying antibacterial and antimicrobial agents and compositions.
    Type: Application
    Filed: March 19, 2015
    Publication date: June 22, 2017
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Beckwith Roger JONATHAN, Rachel DUTTON, Markus ESER, Cristina LANDETA, Jessica L. BLAZYK, Brian M. MEEHAN, Feras HATAHET, Dana BOYD
  • ANTIMICROBIAL AGENTS THAT TARGET BACTERIAL VKOR
    Publication number: 20110243958
    Abstract: Aspects of the invention relate to a method for inhibiting the growth of a microbe that expresses bacterial vitamin K epoxide reductase (bVKOR). The method involves contacting the bacterial cell with an effective amount of an agent that inhibits bVKOR. Agents include a drug, ligand or portion thereof, protein, polypeptide, small organic molecule, antisense nucleic acid, RNAi, or antibody. Examples of useful agents are a phenylpropanoid, a modified phenylpropanoid, a coumarin or modified coumarin. A particularly useful agents is warfarin or a variant thereof or ferulenol or a variant thereof. The microbe is any microbe carrying a bVKOR gene, such as Mycobacterium tuberculosis.
    Type: Application
    Filed: October 14, 2009
    Publication date: October 6, 2011
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Jonathan Beckwith, Rachel Dutton, Dana Boyd, Mehmet Berkmen