Abstract: The invention provides isolated nucleic acids molecules, designated 23479, 48120, and 46689 nucleic acid molecules, which encode novel hydrolases. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 23479, 48120, and 46689 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 23479, 48120, or 46689 gene has been introduced or disrupted. The invention still further provides isolated 23479, 48120, and 46689 proteins, fusion proteins, antigenic peptides and anti-23479, 48120, or 46689 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 16051a and 16051b nucleic acid molecules, which encode novel PDZ family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 16051a or 16051b nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 16051a or 16051b gene has been introduced or disrupted. The invention still further provides isolated 16051a or 16051b proteins, fusion proteins, antigenic peptides and anti-16051a or 16051b antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 33200 nucleic acid molecules, which encode novel dehydrogenase/reductase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33200 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33200 gene has been introduced or disrupted. The invention still further provides isolated 33200 proteins, fusion proteins, antigenic peptides and anti-33200 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 2150 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 2150 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 2150 gene has been introduced or disrupted. The invention still further provides isolated 2150 proteins, fusion proteins, antigenic peptides and anti-2150 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 33217 nucleic acid molecules, which encode novel AMP-binding enzyme members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33217 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33217 gene has been introduced or disrupted. The invention still further provides isolated 33217 proteins, fusion proteins, antigenic peptides and anti-33217 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 56634 nucleic acid molecules, which encode novel phosphatidylinositol 4-phosphate 5-kinase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 56634 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 56634 gene has been introduced or disrupted. The invention still further provides isolated 56634 proteins, fusion proteins, antigenic peptides and anti-56634 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 33521 nucleic acid molecules, which encode novel Rho GEF members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33521 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33521 gene has been introduced or disrupted. The invention still further provides isolated 33521 proteins, fusion proteins, antigenic peptides and anti-33521 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 25206 nucleic acid molecules, which encode novel short-chain dehydrogenase/reductase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 25206 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 25206 gene has been introduced or disrupted. The invention still further provides isolated 25206 proteins, fusion proteins, antigenic peptides and anti-25206 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated m32404 nucleic acid molecules, which encode novel trypsin members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing m32404 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an m32404 gene has been introduced or disrupted. The invention still further provides isolated m32404 proteins, fusion proteins, antigenic peptides and anti-m32404 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 33945 nucleic acid molecules, which encode novel glycosyltransferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33945 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33945 gene has been introduced or disrupted. The invention still further provides isolated 33945 proteins, fusion proteins, antigenic peptides and anti-33945 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 67118, 67067, and 62092 nucleic acid molecules, which encode novel transporter family molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 67118, 67067, and 62092 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 67118, 67067, or 62092 gene has been introduced or disrupted. The invention still further provides isolated 67118, 67067, and/or 62092 polypeptides, fusion polypeptides, antigenic peptides and anti-67118, anti-67067, and anti-62092 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 47169 and 33935 nucleic acid molecules, which encode novel glycosyl transferases. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47169 and 33935 nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a 47169 or 33935 gene has been introduced or disrupted. The invention still further provides isolated 47169 and 33935 proteins, fusion proteins, antigenic peptides and anti-47169 and anti-33935 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acids molecules, designated 33449 nucleic acid molecules, which encode novel protease or S26 signal peptidase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33449 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33449 gene has been introduced or disrupted. The invention still further provides isolated 33449 proteins, fusion proteins, antigenic peptides and anti-33449 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.