Patents by Inventor Rachel E. MUIR

Rachel E. MUIR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microtiter plates for controlled release of culture components to cell cultures
    Patent number: 10030221
    Abstract: The invention provides a culture plate made from a polymer incorporating a culture component releasable into culture media in the well, methods of culturing a microorganisms in the culture plate, and a methods of making the culture plate.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: July 24, 2018
    Assignee: DANISCO US INC.
    Inventors: Jimmy Chan, Rachel E. Muir, William Throndset
  • Enhanced production of isoprene using host cells having decreased activity
    Patent number: 9388431
    Abstract: This invention relates to recombinant microorganisms capable of producing isoprene and isoprene production with the use of such recombinant microorganism with good efficiency. In this invention, functional activity of the ispA gene is altered to reduce the production of isoprenoid molecules in recombinant cells engineered to produce isoprene or in cells otherwise susceptible to isoprenoid accumulation during fermentation. This decreased ispA gene functional activity enables enhanced synthesis of isoprene in a host microorganism.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: July 12, 2016
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Joseph C. McAuliffe, Rachel E. Muir, Alex T. Nielsen, Caroline M. Peres, Dmitrii V. Vaviline, Derek H. Wells
  • ENHANCED PRODUCTION OF ISOPRENE USING HOST CELLS HAVING DECREASED ISPA ACTIVITY
    Publication number: 20150218590
    Abstract: This invention relates to recombinant microorganisms capable of producing isoprene and isoprene production with the use of such recombinant microorganism with good efficiency. In this invention, functional activity of the ispA gene is altered to reduce the production of isoprenoid molecules in recombinant cells engineered to produce isoprene or in cells otherwise susceptible to isoprenoid accumulation during fermentation. This decreased ispA gene functional activity enables enhanced synthesis of isoprene in a host microorganism.
    Type: Application
    Filed: January 9, 2015
    Publication date: August 6, 2015
    Inventors: Joseph C. MCAULIFFE, Rachel E. Muir, Alex T. Nielsen, Caroline M. Peres, Dmitrii V. Vaviline, Derek H. Wells
  • Microtiter plates for controlled release of culture components to cell cultures
    Publication number: 20150147768
    Abstract: The invention provides a culture plate made from a polymer incorporating a culture component releasable into culture media in the well, methods of culturing a microorganisms in the culture plate, and a methods of making the culture plate.
    Type: Application
    Filed: September 20, 2013
    Publication date: May 28, 2015
    Applicant: Danisco US Inc
    Inventors: Jimmy Chan, Rachel E. Muir, William Throndset
  • Enhanced production of isoprene using host cells having decreased ispA activity
    Patent number: 8975051
    Abstract: This invention relates to recombinant microorganisms capable of producing isoprene and isoprene production with the use of such recombinant microorganism with good efficiency. In this invention, functional activity of the ispA gene is altered to reduce the production of isoprenoid molecules in recombinant cells engineered to produce isoprene or in cells otherwise susceptible to isoprenoid accumulation during fermentation. This decreased ispA gene functional activity enables enhanced synthesis of isoprene in a host microorganism.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: March 10, 2015
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Joseph C. McAuliffe, Rachel E. Muir, Alex T. Nielsen, Caroline M. Peres, Dmitrii V. Vaviline, Derek H. Wells
  • BIOLOGICAL PRODUCTION OF PENTOSE SUGARS USING RECOMBINANT CELLS
    Publication number: 20140162322
    Abstract: The invention provides, inter alia, compositions and methods for the biological production of pentose sugars, such as 2-methylerythritol (2-ME), 1-deoxyxylulose (1-DX), and monoacetylated-2-C-methylerythritols, using recombinant cells.
    Type: Application
    Filed: February 13, 2014
    Publication date: June 12, 2014
    Applicant: DANISCO US INC.
    Inventors: Joseph C. MCAULIFFE, Rachel E. MUIR
  • ISOPRENE PRODUCTION USING THE DXP AND MVA PATHWAY
    Publication number: 20140162337
    Abstract: The invention provides for methods for producing isoprene from cultured cells using various components of the DXP pathway and MVA pathway, or components associated with the DXP pathway and MVA pathway, iron-sulfur cluster-interacting redox polypeptides, and isoprene synthase. The invention also provides compositions that include these cultured cells.
    Type: Application
    Filed: July 11, 2013
    Publication date: June 12, 2014
    Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.
    Inventors: Gopal K. CHOTANI, Joseph C. MCAULIFFE, Michael C. MILLER, Rachel E. MUIR, Dmitrii V. VAVILINE, Walter WEYLER
  • COMPOSITIONS AND METHODS FOR IMPROVED ISOPRENE PRODUCTION USING TWO TYPES OF ISPG ENZYMES
    Publication number: 20140147902
    Abstract: The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase.
    Type: Application
    Filed: February 7, 2014
    Publication date: May 29, 2014
    Applicants: THE GOODYEAR TIRE & RUBBER COMPANY, DANISCO US INC.
    Inventors: Rachel E. MUIR, Walter WEYLER
  • Biological production of pentose sugars using recombinant cells
    Patent number: 8691541
    Abstract: The invention provides, inter alia, compositions and methods for the biological production of pentose sugars, such as 2-methylerythritol (2-ME), 1-deoxyxylulose (1-DX), and monoacetylated-2-C-methylerythritols, using recombinant cells.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: April 8, 2014
    Assignee: Danisco US Inc.
    Inventors: Joseph C. McAuliffe, Rachel E. Muir
  • Compositions and methods for improved isoprene production using two types of ISPG enzymes
    Patent number: 8685702
    Abstract: The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: April 1, 2014
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Rachel E. Muir, Walter Weyler
  • Isoprene production using the DXP and MVA pathway
    Patent number: 8507235
    Abstract: The invention provides for methods for producing isoprene from cultured cells using various components of the DXP pathway and MVA pathway, or components associated with the DXP pathway and MVA pathway, iron-sulfur cluster-interacting redox polypeptides, and isoprene synthase. The invention also provides compositions that include these cultured cells.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: August 13, 2013
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Gopal K. Chotani, Joseph C. McAuliffe, Michael C. Miller, Rachel E. Muir, Dmitrii V. Vaviline, Walter Weyler
  • BIOLOGICAL PRODUCTION OF PENTOSE SUGARS USING RECOMBINANT CELLS
    Publication number: 20120329102
    Abstract: The invention provides, inter alia, compositions and methods for the biological production of pentose sugars, such as 2-methylerythritol (2-ME), 1-deoxyxylulose (1-DX), and monoacetylated-2-C-methylerythritols, using recombinant cells.
    Type: Application
    Filed: December 22, 2011
    Publication date: December 27, 2012
    Inventors: Joseph C. MCAULIFFE, Rachel E. MUIR
  • COMPOSITIONS AND METHODS FOR IMPROVED ISOPRENE PRODUCTION USING TWO TYPES OF ISPG ENZYMES
    Publication number: 20120164711
    Abstract: The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 28, 2012
    Applicant: Danisco US Inc.
    Inventors: Rachel E. MUIR, Walter Weyler