Abstract: Provided are methods, compositions and articles of manufacture for use in cell therapy involving the administration of one or more doses of a therapeutic T cell composition, and methods, compositions and articles of manufacture for use in the same. The cells of the T cell composition express recombinant receptors such as chimeric receptors, e.g. chimeric antigen receptors (CARs) or other transgenic receptors such as T cell receptors (TCRs). Features of the embodiments of the present disclosure, including the dose of cells or units of cells administered and/or the phenotype of administered cells, provide various advantages, such as consistent dosing, lower risk of toxicity and/or increased response in subjects administered the T cell compositions.

Abstract: A soft brace to prevent injury to one or more target joints or body segments is disclosed. The soft brace includes one or more tensile elements configured to limit motion of one or more target joints based on placement of the one or more tensile elements relative to the one or more target joints such that the placement and tension of each of the one or more tensile elements provides resistance against motion of the one or more target joints; one or more soft tissue anchors positioned on a body around the one or more target joints, the one or more anchors being configured to anchor one or more of the one or more tensile elements to the body to provide force distribution relative to the one or more target joints; and wherein at least one of the one or more tensile elements is routed in parallel with the approximate center of rotation of at least one of the one or more target joints.

Abstract: The present invention provides, an aircraft passenger seat unit comprising a convertible passenger seat, a shell defining a planform of the seat unit, the planform having a first end region across a first end of the planform, a second end region across the second end of the planform, and a middle region extending from the first end region to the second end region, wherein the second end region is offset from the first end region in a direction transverse to the length of the planform, the shell further comprising a moveable partition being moveable between a raised position and a lowered position, in which a sight line is unblocked, wherein the moveable partition is located adjacent the middle region and wherein, when in the lowered position, the partition is located under the bed height of the converted passenger seat.

Abstract: The present invention relates to a suite, in particular for an aircraft cabin, comprising: a seat, an ottoman, and a storage cupboard, the suite further comprising a movable table capable of assuming: a stowed state in which the movable table extends in a vertical plane, in which the movable table is arranged between the cupboard and the ottoman, and a deployed state in which the movable table extends in a horizontal plane.

Abstract: The present invention relates to a suite, in particular for an aircraft cabin, comprising: a seat, an ottoman, and a storage cupboard, the suite further comprising a movable table capable of assuming: a stowed state in which the movable table extends in a vertical plane, in which the movable table is arranged between the cupboard and the ottoman, and a deployed state in which the movable table extends in a horizontal plane.

Abstract: An aircraft passenger suite (100) is provided. The suite (100) comprises an aircraft seat (110) for use by a passenger. The suite (100) also comprises a controller for controlling a number of output states (240) of the suite, the controller comprising a logic condition receiver operable to receive a logic condition input (210). The suite (100) also comprises sensor equipment operable to provide a sensor input (220) to the controller, the sensor input (220) providing an indication of at least one attribute of a passenger of the suite (100). The sensor equipment comprises one or more of: an image sensor (151, 152) a pressure sensor (154) and a physiological sensor. The controller is configured to control at least one of the output states (240) of the suite based on both the logic condition input (210) and the sensor input (220).

Abstract: The present invention provides, an aircraft passenger seat unit comprising a convertible passenger seat, a shell defining a planform of the seat unit, the planform having a first end region across a first end of the planform, a second end region across the second end of the planform, and a middle region extending from the first end region to the second end region, wherein the second end region is offset from the first end region in a direction transverse to the length of the planform, the shell further comprising a moveable partition being moveable between a raised position and a lowered position, in which a sight line is unblocked, wherein the moveable partition is located adjacent the middle region and wherein, when in the lowered position, the partition is located under the bed height of the converted passenger seat.

Abstract: The present invention provides an aircraft passenger seat unit comprising a seat, a privacy shell having a primary opening to allow entry to and exit from the seat unit, a storage unit comprising one or more holders for supporting clothes and a door movable between a first position in which the door at least partially blocks off the primary opening, and a second position in which the door at least partially closes access to holders of the storage unit. The invention also provides an aircraft passenger seat unit in which the door fully blocks off the primary opening, so that passenger entry and exit is prevented, in the first position. The invention also provides an aircraft passenger seat unit in which the door is arranged to move in a direction offset from an angle of the privacy shell adjacent the opening.

Abstract: A method is provided for treating a tobacco material, comprising treating the tobacco material by steam hydrolysis. Also provided is a tobacco material which has been treated by such a method, or a derivative thereof, and a smoking article which comprises a tobacco material treated by such a method.

Abstract: A metal chelate compound of Formula (1) or a salt thereof: [A-N=N—B] M ??Formula (1) wherein: A is an optionally substituted pyridyl ring; and B is of the Formula (2): wherein: X and W are substituents other than H; M is a metal chelated to A-N=N—B; and n is 0 to 4, also claimed are compositions and inks containing a compound of Formula (1), a process for ink jet printing using the inks and an ink jet printer cartridge containing the ink.

Abstract: A metal chelate compound obtainable from contacting a transition metal salt with a compound of the Formula (1) or a salt thereof: wherein p is 1 to 2. Also compositions, inks, printed substrates, ink-jet cartridges and ink-jet printers.