Abstract: The present invention relates to a composition for use in the treatment of a detached retina, comprising an oil and an additive capable of increasing the extensional viscosity of the oil. The present invention also relates to a method and kit of parts for producing the composition.

Abstract: The present invention relates to a composition for use in the treatment of a detached retina, comprising a dispersion of nanoparticles in a liquid, wherein the nanoparticles have a specific gravity which is higher than that of the liquid and the individual refractive indices of the nanoparticles and the liquid are substantially similar to one another. The present invention also relates to a composition for use in the treatment of a detached retina, comprising a dispersion of silica nanoparticles in a liquid, a method and kit of parts for producing the compositions and a method of treating a detached retina.

Abstract: The present invention relates to a composition for use in the treatment of a detached retina, comprising an oil and an additive capable of increasing the extensional viscosity of the oil. The present invention also relates to a method and kit of parts for producing the composition.

Abstract: The present invention relates to novel substrates, to methods of making them and to uses therefor. The substrates of the invention comprise a base portion and a surface layer covering at least part of the base portion, with a binding layer provided therebetween. The surface layer provides, on at least a part of the substrate, topographical features having at least one nano scale dimension. These topographical features are adapted to facilitate, influence, control or inhibit cell or tissue growth thereon and/or therebetween and the substrate may be used for the study, manipulation or modification of at least one cellular or tissue behavior or response.

Abstract: The present invention relates to novel substrates, to methods of making them and to uses therefor. The substrates of the invention comprise a base portion and a surface layer covering at least part of the base portion, with a binding layer provided therebetween. The surface layer provides, on at least a part of the substrate, topographical features having at least one nano scale dimension. These topographical features are adapted to facilitate, influence, control or inhibit cell or tissue growth thereon and/or therebetween and the substrate may be used for the study, manipulation or modification of at least one cellular or tissue behaviour or response.

Abstract: The invention concerns the use of a biomaterial substrate to orient cell or tissue growth. The substrate comprises a base portion and a surface layer covering at least part of the base portion. The surface layer provides the substrate with topographical features having at least one nanoscale dimension of from about 1 to about 200 nm. The topographical features having the capacity to orient cell or tissue growth thereon and/or therebetween.